The power of RNA
RNA-based treatments offer significant promise for new precision therapies for mental health and neurological disorders. The field is rapidly progressing toward the development of new diagnostic and therapeutic tools for brain disorders.
The Centre for RNA in Neuroscience at QBI was established to spearhead the development and application of this new and exciting technology.
Latest News
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Researchers discover new classes of RNA for learning and memory
28 November 2023 -
‘Junk DNA’ key to controlling fear
23 March 2022
Latest Publications
Kirmes, Ina, Hung, Grace Ching Ching, Hahn, Anne, Dai, Chuan-Yang, Campbell, Daniel, Ahier, Arnaud, Lee, Rachel Shin Yie, Palmer, Alexander, and Zuryn, Steven (2025). The microRNA miR-71 suppresses maladaptive UPRmt signaling through both cell-autonomous and cell-non-autonomous mechanisms. Nature Communications 17 (1) 510 . https://doi.org/10.1038/s41467-025-67198-2.
Walsh, Alexander D. and Bredy, Timothy W. (2025). Noncoding RNA gives agency to the molecular and cellular substrates of learning and memory. Current Opinion in Neurobiology 93 103044 1-8. https://doi.org/10.1016/j.conb.2025.103044.
Davies, Joshua William Ashley, Bredy, Timothy William, and Marshall, Paul Robert (2025). Cutting-edge RNA technologies to advance the understanding of learning and memory. Neurobiology of Learning and Memory 219 108050 108050. https://doi.org/10.1016/j.nlm.2025.108050.
Marshall, Paul R., Davies, Joshua, Zhao, Qiongyi, Liau, Wei-Siang, Lee, Yujin, Basic, Dean, Periyakaruppiah, Ambika, Zajaczkowski, Esmi L., Leighton, Laura J., Madugalle, Sachithrani U., Musgrove, Mason, Kielar, Marcin, Brueckner, Arie Maeve, Gong, Hao, Ren, Haobin, Walsh, Alexander, Kaczmarczyk, Lech, Jackson, Walker S., Chen, Alon, Spitale, Robert C., and Bredy, Timothy W. (2024). DNA G-quadruplex is a transcriptional control device that regulates memory. The Journal of Neuroscience 44 (15) e0093232024 1-20. https://doi.org/10.1523/jneurosci.0093-23.2024.
Chen, Claire C., Han, Joseph, Chinn, Carlene A., Rounds, Jacob S., Li, Xiang, Nikan, Mehran, Myszka, Marie, Tong, Liqi, Passalacqua, Luiz F. M., Bredy, Timothy, Wood, Marcelo A., and Luptak, Andrej (2024). Inhibition of Cpeb3 ribozyme elevates CPEB3 protein expression and polyadenylation of its target mRNAs, and enhances object location memory. eLife 13 e90116 . https://doi.org/10.7554/elife.90116