Professor Helen Cooper: Neural migration

Current research in the Cooper laboratory explores the fundamental cellular and molecular mechanisms governing the development of the neocortex. The group has identified unexpected, novel roles for the axon guidance receptors Neogenin (a netrin receptor) and Ryk (a Wnt receptor) in neural stem cell biology, neurogenesis, dendrite outgrowth and synaptogenesis. The Cooper group has shown that loss of these receptors in the mouse leads to cortical malformations which are equivalent to those seen in humans.

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