Associate Professor Victor Anggono: Synaptic neurobiology

Our research combines biochemical, molecular and cellular biology in both cell culture (primary neurons and cell lines) and mouse models. We utilise gene editing technology, cutting-edge microscopy, proteomics, next-generation sequencing and behavioural analyses in our study. We are particularly interested in understanding the complex neuronal signalling cascades through protein-protein interactions and post-translational modifications of key synaptic molecules.

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Researcher biography

Victor Anggono received his PhD in 2007 from the University of Sydney and undertook his postdoctoral training at the Johns Hopkins University in Baltimore, USA. In 2012, Dr Anggono returned to Australia as an NHMRC CJ Martin Research Fellow and joined the Queensland Brain Institute at the University of Queensland, where he is currently a Senior Research Fellow and Group Leader at the Clem Jones Centre for Ageing Dementia Research. His research aims to understand the molecular mechanisms of synaptic vesicle and glutamate receptor trafficking in neurons, processes that are essential for synaptic transmission, plasticity, learning and memory, and how their dysregulations impact on the pathophysiology of neurodegenerative diseases and neuropsychiatric disorders. Dr Anggono has published in journals such as Nature Neuroscience, Neuron, The Proceedings of the National Academy of Sciences USA, Journal of Neuroscience and Cell Reports, and has attracted more than 1500 citations. For his works, Dr Anggono was awarded the Boomerang Award (Australian Society for Biochemistry and Molecular Biology, 2011), the Young Scientist Award (Federation of Asian and Oceanian Biochemists and Molecular Biologists, 2015), the Science to Art Award (NHMRC, 2015) and more recently the Young Investigator Award (Asian-Pacific Society for Neurochemistry, 2016).