Clem Jones Centre for Ageing Dementia Research (CJCADR)
The Clem Jones Centre for Ageing Dementia Research (CJCADR), housed within the Queensland Brain Institute at The University of Queensland, is Australia's first and largest research centre dedicated to the prevention and treatment of dementia. Professor Jürgen Götz, a world leader in conducting cutting-edge research in Alzheimer’s disease, is the inaugural Director of the Centre. CJCADR is driven by the insight that fundamental, basic research is required to provide a solution to the ageing crisis as diseases including Alzheimer's pose an increasing challenge to our society. The Centre currently has 10 laboratories of researchers.
What is dementia?
Dementia is not a single disease but rather a term to describe a number of illnesses that predominantly affect people over the age of 65. It is important to remember that not all older people get dementia. It is not a normal part of ageing. Dementia is a progressive brain disorder that affects a person’s ability to function normally. The condition involves the degeneration of brain cells, with common symptoms including memory loss, confusion, personality change, withdrawal and a loss of ability to do everyday tasks.
There are many different forms of dementia. The most common types of dementia are Alzheimer’s disease, vascular dementia, Parkinson’s disease, Dementia with Lewy bodies, Fronto Temporal Lobar Degeneration, Huntington’s disease, Alcohol related dementia (Korsakoff’s syndrome) and Creutzfeldt-Jacob disease.
Ageing dementia is one of the country’s most pressing health problems. Alzheimer’s affects more than two-thirds of dementia patients, and approximately a quarter of a million Australians. The total number of dementia cases in Australia is expected to rise to 900,000 by 2050. It presents significant challenges to the health care system, which makes directed research programs aimed at preventing and treating ageing dementia all the more urgent.
Led by Professor Jürgen Götz, CJCADR scientists are developing a non-invasive ultrasound technology to treat Alzheimer’s disease and restore memory. The approach temporarily opens the blood brain barrier, activating mechanisms that clear toxic protein clumps and restoring memory functions. Research has been conducted in mouse models and is being scaled up in higher animal models. Human clinical trials are two to three years away.
Findings of the research, Scanning ultrasound efficiently removes amyloid β and restores memory in an Alzheimer’s model, are published in the journal Science Translational Medicine.
Keep up to date with research developments at CJCADR.
Using ultrasound to treat dementia
What can be done to help?
Currently there is no prevention or cure; however, some medications reduce some of the symptoms. Enquiries on current clinical trials of new medications can be forwarded to Liz Arnold, Discipline of Psychiatry, School of Medicine, The University of Queensland, K Floor, Mental Health Centre, RBWH Herston Qld 4029, Tel: + 61 7 3365 5147, Email: email@example.com
National Dementia Helpline on 1800 100 500 QLD: firstname.lastname@example.org
The National Dementia Helpline is a telephone information and support service available across Australia. The Helpline is for people with dementia, their carers, families and friends, as well as people concerned about memory loss. It is also used by health professionals, service providers, community organisations and students.
Alzheimer’s Australia Queensland
Alzheimer’s Australia (Qld) offers a range of services for people with dementia, family carers, industry workers and anyone who wants to know more about memory loss, dementia or good brain health.