We study the underlying biological basis for schizophrenia, with the goal of finding public health interventions that will alleviate the burden of this disease.
The laboratory has been exploring the impact of developmental vitamin D deficiency on brain development, the impact of adult vitamin D deficiency on brain function and behaviour and, more recently, has been establishing novel ways to assess cognitive behaviour in rodents.
In 2015, the Burne laboratory built on previous research on low prenatal vitamin D (the “sunshine hormone”) to show that adult vitamin D deficiency is also associated with alterations in behaviour, brain neurochemistry and receptor profiles. They have discovered that low vitamin D levels during adulthood affect the balance of excitatory and inhibitory neurotransmitters in the brain, and also alter cognitive behaviour in rodents. These results provide the first evidence in mice to show that adult vitamin D deficiency impacts on neurotransmitter systems that are affected in a number of neuropsychiatric conditions, including autism, schizophrenia and depression.
Ongoing NHMRC funding allows the laboratory to dissect the exact neural pathways involved in cognitive impairments of attentional processing in vitamin D–deficient animals to model the cognitive symptoms of schizophrenia.
The Burne laboratory has also created and validated a unique cognitive task for rodents that mirrors the continuous performance task in humans. The laboratory’s goal is to provide a novel tool for cognitive research in rodents and to uncover more about the pathophysiology and drug treatment of cognitive symptoms in schizophrenia.
Group leader
Professor Thomas Burne
Group Leader, Developmental neurobiology
Conjoint Principal Research Fellow
+61 7 334 66371
t.burne@uq.edu.au
UQ Researcher Profile
- Professor John McGrath, The University of Queensland
- Associate Professor Darryl Eyles, The University of Queensland
- Professor Alan Mackay-Sim, Griffith University
- Dr Amy Johnston, Griffith University
- Dr Tim Karl, Prince of Wales Medical Research Institute
- Associate Professor Chao Deng, University of Wollongong
- Professor Fred Meunier, The University of Queensland
- Associate Professor Karen Moritz, The University of Queensland
- Dr Ethan Scott, The University of Queensland
- Dr Suyinn Chong, Mater Research
- Associate Professor Bruno van Swinderen, The University of Queensland
Conn, Kyna-Anne, Zou, Simin, Das, Joyosmita, Alexander, Suzy, Burne, Thomas HJ. and Kesby, James P. (2023). Activating the dorsomedial and ventral midbrain projections to the striatum differentially impairs goal-directed action in male mice. Neuropharmacology 109550, 109550. doi: 10.1016/j.neuropharm.2023.109550
Atcheson, Ranita J., Burne, Thomas H. J. and Dawson, Paul A. (2022). Serum sulfate level and Slc13a1 mRNA expression remain unaltered in a mouse model of moderate vitamin D deficiency. Molecular and Cellular Biochemistry, 1-7. doi: 10.1007/s11010-022-04634-7
Young, Madison K., Conn, Kyna-Anne, Das, Joyosmita, Zou, Simin, Alexander, Suzy, Burne, Thomas H.J. and Kesby, James P. (2022). Activity in the dorsomedial striatum underlies serial reversal learning performance under probabilistic uncertainty. Biological Psychiatry Global Open Science. doi: 10.1016/j.bpsgos.2022.08.005
Groves, Natalie J., Josh, Peter, McGrath, John J., Kurniawan, Nyoman D. and Burne, Thomas H.J. (2022). Adult vitamin D deficiency impairs hippocampal-dependent memory and proteins related to synaptic plasticity and metabolism in mice. Journal of Brain Disorders, 3 (1). doi: 10.36959/524/331
Sanchez Vega, M., Harris, L., Chong, S. and Burne, T. (2022). Interaction of developmental vitamin D deficiency and ethanol exposure on maternal metabolism and neonatal gene expression. Trends in Developmental Biology, 14, 33-52.
Al-Amin, Md. Mamun, Sullivan, Robert K. P., Alexander, Suzy, Carter, David A., Bradford, DanaKai and Burne, Thomas H. J. (2022). Impaired spatial memory in adult vitamin D deficient BALB/c mice is associated with reductions in spine density, nitric oxide, and neural nitric oxide synthase in the hippocampus. AIMS Neuroscience, 9 (1), 31-56. doi: 10.3934/Neuroscience.2022004
Flintoff, Jonathan, Kesby, James P., Siskind, Dan and Burne, Thomas H. J. (2021). Treating cognitive impairment in schizophrenia with GLP-1RAs: an overview of their therapeutic potential. Expert Opinion on Investigational Drugs, 30 (8), 877-891. doi: 10.1080/13543784.2021.1951702
Elp2 mutations perturb the epitranscriptome and lead to a complex neurodevelopmental phenotype
Kojic, Marija, Gawda, Tomasz, Gaik, Monika, Begg, Alexander, Salerno-Kochan, Anna, Kurniawan, Nyoman D., Jones, Alun, Drożdżyk, Katarzyna, Kościelniak, Anna, Chramiec-Głąbik, Andrzej, Hediyeh-Zadeh, Soroor, Kasherman, Maria, Shim, Woo Jun, Sinniah, Enakshi, Genovesi, Laura A., Abrahamsen, Rannvá K., Fenger, Christina D., Madsen, Camilla G., Cohen, Julie S., Fatemi, Ali, Stark, Zornitza, Lunke, Sebastian, Lee, Joy, Hansen, Jonas K., Boxill, Martin F., Keren, Boris, Marey, Isabelle, Saenz, Margarita S., Brown, Kathleen ... Wainwright, Brandon J. (2021). Elp2 mutations perturb the epitranscriptome and lead to a complex neurodevelopmental phenotype. Nature Communications, 12 (1) 2678, 2678. doi: 10.1038/s41467-021-22888-5
Vitamin D and schizophrenia: 20 years on
Cui, Xiaoying, McGrath, John J., Burne, Thomas H. J. and Eyles, Darryl W. (2021). Vitamin D and schizophrenia: 20 years on. Molecular Psychiatry, 26 (7), 2708-2720. doi: 10.1038/s41380-021-01025-0
Sanchez Vega, Michelle C., Chong, Suyinn and Burne, Thomas H. J. (2020). Prenatal vitamin D deficiency and prenatal ethanol exposure as modifiable risk factors for neurodevelopmental disorders. SL Nutrition and Metabolism, 3 (1) 125.
Abnormal behavior and cortical connectivity deficits in mice lacking Usp9x
Kasherman, Maria A., Currey, Laura, Kurniawan, Nyoman D., Zalucki, Oressia, Vega, Michelle Sanchez, Jolly, Lachlan A., Burne, Thomas H. J., Wood, Stephen A. and Piper, Michael (2020). Abnormal behavior and cortical connectivity deficits in mice lacking Usp9x. Cerebral Cortex, 31 (3), 1763-1775. doi: 10.1093/cercor/bhaa324
Subcortical dopamine and cognition in schizophrenia: looking beyond psychosis in preclinical models
Conn, Kyna-Anne, Burne, Thomas H. J. and Kesby, James P. (2020). Subcortical dopamine and cognition in schizophrenia: looking beyond psychosis in preclinical models. Frontiers in Neuroscience, 14 542, 542. doi: 10.3389/fnins.2020.00542
Genome-wide association study identifies 143 loci associated with 25 hydroxyvitamin D concentration
Revez, Joana A., Lin, Tian, Qiao, Zhen, Xue, Angli, Holtz, Yan, Zhu, Zhihong, Zeng, Jian, Wang, Huanwei, Sidorenko, Julia, Kemper, Kathryn E., Vinkhuyzen, Anna A. E., Frater, Julanne, Eyles, Darryl, Burne, Thomas H. J., Mitchell, Brittany, Martin, Nicholas G., Zhu, Gu, Visscher, Peter M., Yang, Jian, Wray, Naomi R. and McGrath, John J. (2020). Genome-wide association study identifies 143 loci associated with 25 hydroxyvitamin D concentration. Nature Communications, 11 (1) 1647, 1-12. doi: 10.1038/s41467-020-15421-7
Investigating cortical features of Sotos syndrome using mice heterozygous for Nsd1
Oishi, Sabrina, Zalucki, Oressia, Sanchez Vega, Michelle, Harkins, Danyon, Harvey, Tracey J., Kasherman, Maria, Davila, Raul A., Hale, Lauren, White, Melissa, Piltz, Sandra, Thomas, Paul, Burne, Thomas H.J., Harris, Lachlan and Piper, Michael (2020). Investigating cortical features of Sotos syndrome using mice heterozygous for Nsd1. Genes, Brain and Behavior, 19 (4) e12637, e12637. doi: 10.1111/gbb.12637
The ubiquitin system: a regulatory hub for intellectual disability and autism spectrum disorder
Kasherman, Maria A., Premarathne, Susitha, Burne, Thomas H. J., Wood, Stephen A. and Piper, Michael (2020). The ubiquitin system: a regulatory hub for intellectual disability and autism spectrum disorder. Molecular Neurobiology, 57 (5), 2179-2193. doi: 10.1007/s12035-020-01881-x
Johnson, Brett V., Kumar, Raman, Oishi, Sabrina, Alexander, Suzy, Kasherman, Maria, Vega, Michelle Sanchez, Ivancevic, Atma, Gardner, Alison, Domingo, Deepti, Corbett, Mark, Parnell, Euan, Yoon, Sehyoun, Oh, Tracey, Lines, Matthew, Lefroy, Henrietta, Kini, Usha, Van Allen, Margot, Grønborg, Sabine, Mercier, Sandra, Küry, Sébastien, Bézieau, Stéphane, Pasquier, Laurent, Raynaud, Martine, Afenjar, Alexandra, Billette de Villemeur, Thierry, Keren, Boris, Désir, Julie, Van Maldergem, Lionel, Marangoni, Martina ... Jolly, Lachlan A. (2020). Partial loss of USP9X function leads to a male neurodevelopmental and behavioural disorder converging on TGFβ signalling. Biological Psychiatry, 87 (2), 100-112. doi: 10.1016/j.biopsych.2019.05.028
Usp9X Controls Ankyrin-Repeat Domain Protein Homeostasis during Dendritic Spine Development
Yoon, Sehyoun, Parnell, Euan, Kasherman, Maria, Forrest, Marc P., Myczek, Kristoffer, Premarathne, Susitha, Sanchez Vega, Michelle C., Piper, Michael, Burne, Thomas H. J., Jolly, Lachlan A., Wood, Stephen A. and Penzes, Peter (2019). Usp9X Controls Ankyrin-Repeat Domain Protein Homeostasis during Dendritic Spine Development. Neuron, 105 (3), 506-521.e7. doi: 10.1016/j.neuron.2019.11.003
Gooch, Helen, Cui, Xiaoying, Anggono, Victor, Trzaskowski, Maciej, Tan, Men Chee, Eyles, Darryl W., Burne, Thomas H. J., Jang, Se Eun, Mattheisen, Manuel, Hougaard, David M., Pedersen, Bent Nørgaard, Cohen, Arieh, Mortensen, Preben B., Sah, Pankaj and McGrath, John J. (2019). 1,25-Dihydroxyvitamin D modulates L-type voltage-gated calcium channels in a subset of neurons in the developing mouse prefrontal cortex. Translational Psychiatry, 9 (1) 281, 281. doi: 10.1038/s41398-019-0626-z
Overeem, Kathie, Alexander, Suzy, Burne, Thomas H J, Ko, Pauline and Eyles, Darryl W (2019). Developmental vitamin D deficiency in the rat impairs recognition memory, but has no effect on social approach or hedonia. Nutrients, 11 (11) 2713, 2713. doi: 10.3390/nu11112713
Zalucki, Oressia, Harris, Lachlan, Harvey, Tracey J., Harkins, Danyon, Widagdo, Jocelyn, Oishi, Sabrina, Matuzelski, Elise, Yong, Xuan Ling Hilary, Schmidt, Hannes, Anggono, Victor, Burne, Thomas H. J., Gronostajski, Richard M. and Piper, Michael (2019). NFIX-mediated inhibition of neuroblast branching regulates migration within the adult mouse ventricular–subventricular zone. Cerebral Cortex, 29 (8), 3590-3604. doi: 10.1093/cercor/bhy233
Jaeschke, Kara N. , Blackmore, Daniel G. , Groves, Natalie J. , Al-Amin, Md. Mamun , Alexander, Suzy and Burne, Thomas H. J. (2019). Vitamin D Levels Are Not Associated with Hippocampal-Dependent Learning in Young Adult Male C57BL/6J Mice: A Negative Report. Journal of Psychiatry and Brain Science. doi: 10.20900/jpbs.20190008
Vitamin D in synaptic plasticity, cognitive function, and neuropsychiatric illness
Mayne, Phoebe E. and Burne, Thomas H.J. (2019). Vitamin D in synaptic plasticity, cognitive function, and neuropsychiatric illness. Trends in Neurosciences, 42 (4), 293-306. doi: 10.1016/j.tins.2019.01.003
Cyclooctatetraene: a bioactive cubane paradigm complement
Xing, Hui, Houston, Sevan D., Chen, Xuejie, Ghassabian, Sussan, Fahrenhorst-Jones, Tyler, Kuo, Andy, Murray, Cody-Ellen P., Conn, Kyna-Anne, Jaeschke, Kara N., Jin, Da-Yun, Pasay, Cielo, Bernhardt, Paul V., Burns, Jed M., Tsanaktsidis, John, Savage, G. Paul, Boyle, Glen M., De Voss, James J., McCarthy, James, Walter, Gimme H., Burne, Thomas H. J., Smith, Maree T., Tie, Jian-Ke and Williams, Craig M. (2019). Cyclooctatetraene: a bioactive cubane paradigm complement. Chemistry: A European Journal, 25 (11), 2729-2734. doi: 10.1002/chem.201806277
Al-Amin, Md. Mamun, Sullivan, Robert K. P., Kurniawan, Nyoman D. and Burne, Thomas H. J. (2019). Adult vitamin D deficiency disrupts hippocampal-dependent learning and structural brain connectivity in BALB/c mice. Brain Structure and Function, 224 (3), 1315-1329. doi: 10.1007/s00429-019-01840-w
Sanchez Vega, M., Chong, S. and Burne, T.H.J. (2019). Prenatal vitamin D deficiency does not exacerbate behavioural impairments associated with prenatal ethanol exposure in juvenile male mice. Behavioural Brain Research, 356, 127-136. doi: 10.1016/j.bbr.2018.08.018
The association between neonatal vitamin D status and risk of schizophrenia
Eyles, Darryl W., Trzaskowski, Maciej, Vinkhuyzen, Anna A. E., Mattheisen, Manuel, Meier, Sandra, Gooch, Helen, Anggono, Victor, Cui, Xiaoying, Tan, Men Chee, Burne, Thomas H. J., Jang, Se Eun, Kvaskoff, David, Hougaard, David M., Nørgaard-Pedersen, Bent, Cohen, Arieh, Agerbo, Esben, Pedersen, Carsten B., Børglum, Anders D., Mors, Ole, Sah, Pankaj, Wray, Naomi R., Mortensen, Preben B. and McGrath, John J. (2018). The association between neonatal vitamin D status and risk of schizophrenia. Scientific Reports, 8 (1) 17692, 17692. doi: 10.1038/s41598-018-35418-z
Heterozygosity for Nuclear Factor One X in mice models features of Malan syndrome
Oishi, Sabrina, Harkins, Danyon, Kurniawan, Nyoman D., Kasherman, Maria, Harris, Lachlan, Zalucki, Oressia, Gronostajski, Richard M., Burne, Thomas H.J. and Piper, Michael (2018). Heterozygosity for Nuclear Factor One X in mice models features of Malan syndrome. EBioMedicine, 39, 388-400. doi: 10.1016/j.ebiom.2018.11.044
Functional and molecular changes in the nucleus accumbens of MK-801-sensitized rats
Lefevre, Emilia, Gooch, Helen, Josh, Peter, Alexander, Suzy, Eyles, Darryl W. and Burne, Thomas H. J. (2018). Functional and molecular changes in the nucleus accumbens of MK-801-sensitized rats. Behavioural Pharmacology, 30 (5), 1-395. doi: 10.1097/FBP.0000000000000447
Increasing paternal age alters anxiety-related behaviour in adult mice
Foldi, Claire J., Eyles, Darryl W., McGrath, John J. and Burne, Thomas H. J. (2018). Increasing paternal age alters anxiety-related behaviour in adult mice. Genes, Brain and Behavior, 18 (2) e12522, e12522. doi: 10.1111/gbb.12522
Miliku, Kozeta, Felix, Janine F., Voortman, Trudy, Tiemeier, Henning, Eyles, Darryl W., Burne, Thomas H., McGrath, John J. and Jaddoe, Vincent W. V. (2018). Associations of maternal and fetal vitamin D status with childhood body composition and cardiovascular risk factors. Maternal and Child Nutrition, 15 (2) e12672, e12672. doi: 10.1111/mcn.12672
Zalucki, Oressia, Harkins, Danyon, Harris, Lachlan, Burne, Thomas H. J., Gronostajski, Richard M. and Piper, Michael (2018). Analysis of hippocampal-dependent learning and memory behaviour in mice lacking Nfix from adult neural stem cells. BMC Research Notes, 11 (1) 564, 564. doi: 10.1186/s13104-018-3652-7
Langguth, M., Fassin, M., Alexander, S., Turner, K. M. and Burne, T. H. J. (2018). No effect of prenatal vitamin D deficiency on autism-relevant behaviours in multiple inbred strains of mice. Behavioural Brain Research, 348, 42-52. doi: 10.1016/j.bbr.2018.04.004
Harris, Lachlan, Zalucki, Oressia, Gobius, Ilan, McDonald, Hannah, Osinki, Jason, Harvey, Tracey J., Essebier, Alexandra, Vidovic, Diana, Gladwyn-Ng, Ivan, Burne, Thomas H., Heng, Julian I., Richards, Linda J., Gronostajski, Richard M. and Piper, Michael (2018). Erratum: Correction: Transcriptional regulation of intermediate progenitor cell generation during hippocampal development (doi: 10.1242/dev.140681) (Development (Cambridge, England) (2016) 143 24 (4620-4630) PII: dev169631). Development (Cambridge), 145 (14). doi: 10.1242/dev.169631
Harris, Lachlan, Zalucki, Oressia, Clément, Olivier, Fraser, James, Matuzelski, Elise, Oishi, Sabrina, Harvey, Tracey J., Burne, Thomas H. J., Heng, Julian Ik-Tsen, Gronostajski, Richard M. and Piper, Michael (2018). Neurogenic differentiation by hippocampal neural stem and progenitor cells is biased by NFIX expression. Development (Cambridge, England), 145 (3) dev155689, 1-12. doi: 10.1242/dev.155689
Al-Amin, Mamun, Bradford, DanaKai, Sullivan, Robert K. P., Kurniawan, Nyoman D., Moon, Yeonsil, Han, Seol-Heui, Zalesky, Andrew and Burne, Thomas H. J. (2018). Vitamin D deficiency is associated with reduced hippocampal volume and disrupted structural connectivity in patients with mild cognitive impairment. Human Brain Mapping, 40 (2), 394-406. doi: 10.1002/hbm.24380
Touchscreen-based visual discrimination and reversal tasks for mice to test cognitive flexibility
Turner, Karly M., Simpson, Christopher G. and Burne, Thomas H. J. (2017). Touchscreen-based visual discrimination and reversal tasks for mice to test cognitive flexibility. Bio-protocol, 7 (20) e2583, e2583. doi: 10.21769/bioprotoc.2583
Groves, Natalie J., Zhou, Mei, Jhaveri, Dhanisha J., McGrath, John J. and Burne, Thomas H. J. (2017). Adult vitamin D deficiency exacerbates impairments caused by social stress in BALB/c and C57BL/6 mice. Psychoneuroendocrinology, 86, 53-63. doi: 10.1016/j.psyneuen.2017.09.003
Harris, Lachlan, Zalucki, Oressia, Oishi, Sabrina, Burne, Thomas H., Jhaveri, Dhanisha J. and Piper, Michael (2017). A morphology independent approach for identifying dividing adult neural stem cells in the mouse hippocampus. Developmental Dynamics, 247 (1), 194-200. doi: 10.1002/dvdy.24545
Content specificity of attentional bias to threat in post-traumatic stress disorder
Zinchenko, A., Al-Amin, M. M., Alam, M. M., Mahmud, W., Kabir, N., Reza, H. M. and Burne, T. H. J. (2017). Content specificity of attentional bias to threat in post-traumatic stress disorder. Journal of Anxiety Disorders, 50, 33-39. doi: 10.1016/j.janxdis.2017.05.006
Kesby, James P., Turner, Karly M., Alexander, Suzanne, Eyles, Darryl W., McGrath, John J. and Burne, Thomas H.J. (2017). Developmental vitamin D deficiency alters multiple neurotransmitter systems in the neonatal rat brain. International Journal of Developmental Neuroscience, 62 (C), 1-7. doi: 10.1016/j.ijdevneu.2017.07.002
Moe, Aung Aung Kywe, Medely, Gregory A., Reeks, Timothy, Burne, Thomas H. J. and Eyles, Darryl W. (2017). Short- and long-term effects of risperidone on catalepsy sensitisation and acquisition of conditioned avoidance response: adolescent vs adult rats. Pharmacological Research, 121, 1-13. doi: 10.1016/j.phrs.2017.04.013
Effect of the glucocorticoid receptor antagonist RU486 on MK-801 induced behavioural sensitization
Lefevre, Emilia M., Medley, Gregory A., Reeks, Timothy, Alexander, Suzy, Burne, Thomas H. J. and Eyles, Darryl W. (2017). Effect of the glucocorticoid receptor antagonist RU486 on MK-801 induced behavioural sensitization. PLoS One, 12 (4) e0176156, e0176156. doi: 10.1371/journal.pone.0176156
Turner, Karly M., Peak, James and Burne, Thomas H. J. (2017). Baseline-dependent effects of amphetamine on attention are associated with striatal dopamine metabolism. Scientific Reports, 7 (1) 297, 297. doi: 10.1038/s41598-017-00437-9
Gestational vitamin D deficiency and autism spectrum disorder
Vinkhuyzen, Anna A. E., Eyles, Darryl W., Burne, Thomas H. J., Blanken, Laura M. E., Kruithof, Claudia J., Verhulst, Frank, White, Tonya, Jaddoe, Vincent W., Tiemeier, Henning and McGrath, John J. (2017). Gestational vitamin D deficiency and autism spectrum disorder. BJPsych Open, 3 (2), 85-90. doi: 10.1192/bjpo.bp.116.004077
The impact of vitamin D deficiency on neurogenesis in the adult brain
Groves, Natalie J. and Burne, Thomas H. J. (2017). The impact of vitamin D deficiency on neurogenesis in the adult brain. Neural Regeneration Research, 12 (3), 393-394. doi: 10.4103/1673-5374.202936
BALB/c mice can learn touchscreen visual discrimination and reversal tasks faster than C57BL/6 mice
Turner, Karly M., Simpson, Christopher G. and Burne, Thomas H. J. (2017). BALB/c mice can learn touchscreen visual discrimination and reversal tasks faster than C57BL/6 mice. Frontiers in Behavioral Neuroscience, 11 16, 16. doi: 10.3389/fnbeh.2017.00016
Impact of combined adult vitamin D deficiency and second-hit exposures on brain function
Al-Amin, Md Mamun, Sullivan, Robert K. P., Jaeschke, Kara N. and Burne, Thomas H. J. (2017). Impact of combined adult vitamin D deficiency and second-hit exposures on brain function. CAB Reviews: Perspectives in Agriculture, Veterinary Science, Nutrition and Natural Resources, 12 (040), 1-16. doi: 10.1079/PAVSNNR201712040
Transcriptional regulation of intermediate progenitor cell generation during hippocampal development
Harris, Lachlan, Zalucki, Oressia, Gobius, Ilan, McDonald, Hannah, Osinki, Jason, Harvey, Tracey J., Essebier, Alexandra, Vidovic, Diana, Gladwyn-Ng, Ivan, Burne, Thomas H., Heng, Julian I., Richards, Linda J., Gronostajski, Richard M. and Piper, Michael (2016). Transcriptional regulation of intermediate progenitor cell generation during hippocampal development. Development, 143 (24), 4620-4630. doi: 10.1242/dev.140681
Gestational vitamin D deficiency and autism-related traits: the Generation R Study
Vinkhuyzen, A. A. E., Eyles, D. W., Burne, T. H. J., Blanken, L. M. E., Kruithof, C. J., Verhulst, F., Jaddoe, V. W., Tiemeier, H. and McGrath, J. J. (2016). Gestational vitamin D deficiency and autism-related traits: the Generation R Study. Molecular Psychiatry, 23 (2), 240-246. doi: 10.1038/mp.2016.213
Improvement of attention with amphetamine in low- and high-performing rats
Turner, Karly M. and Burne, Thomas H. J. (2016). Improvement of attention with amphetamine in low- and high-performing rats. Psychopharmacology, 233 (18), 3383-3394. doi: 10.1007/s00213-016-4376-9
Moe, Aung Aung Kywe, Kurniawan, Nyoman D., Alexander, Suzanne, Cui, Xiaoying, Burne, Thomas H. J. and Eyles, Darryl W. (2016). Risperidone induces long-lasting changes in the conditioned avoidance response and accumbal gene expression selectively in animals treated as adolescents. Neuropharmacology, 108, 264-274. doi: 10.1016/j.neuropharm.2016.04.035
Moe, Aung Aung Kywe, Scott, James G., Burne, Thomas H. J. and Eyles, Darryl W. (2016). Neural changes induced by antipsychotic administration in adolescence: a review of studies in laboratory rodents. Journal of Psychopharmacology, 30 (8), 771-794. doi: 10.1177/0269881116654776
Miliku, Kozeta, Vinkhuyzen, Anna, Blanken, Laura M. E., McGrath, John J., Eyles, Darryl W., Burne, Thomas H., Hofman, Albert, Tiemeier, Henning, Steegers, Eric A. P., Gaillard, Romy and Jaddoe, Vincent W. V. (2016). Maternal vitamin D concentrations during pregnancy, fetal growth patterns, and risks of adverse birth outcomes. American Journal of Clinical Nutrition, 103 (6), 1514-1522. doi: 10.3945/ajcn.115.123752
Usp9x-deficiency disrupts the morphological development of the postnatal hippocampal dentate gyrus
Oishi, Sabrina, Premaratne, Susitha, Harvey, Tracey J., Iyer, Swati, Dixon, Chantelle, Alexander, Suzanne, Burne, Thomas H. J., Wood, Stephen A. and Piper, Michael (2016). Usp9x-deficiency disrupts the morphological development of the postnatal hippocampal dentate gyrus. Scientific Reports, 6 (1) 25783, 25783.1-25783.13. doi: 10.1038/srep25783
Gazibara, Tatjana, Elbert, Niels J., den Dekker, Herman T., de Jongste, Johan C., Reiss, Irwin, McGrath, John J., Eyles, Darryl W., Burne, Thomas H., Tiemeier, Henning, Jaddoe, Vincent W. V., Pasmans, Suzanne G. M. A. and Duijts, Liesbeth (2016). Associations of maternal and fetal 25-hydroxyvitamin D levels with childhood eczema: The Generation R Study. Pediatric Allergy and Immunology, 27 (3), 283-289. doi: 10.1111/pai.12530
Groves, Natalie J., Bradford, DanaKai, Sullivan, Robert K. P., Conn, Kyna-Anne, Aljelaify, Rasha Fahad, McGrath, John J. and Burne, Thomas H. J. (2016). Behavioural effects of adult Vitamin D deficiency in BALB/c mice are not associated with proliferation or survival of neurons in the adult hippocampus. PLoS ONE, 11 (4) e0152328, e0152328. doi: 10.1371/journal.pone.0152328
Sex-specific attentional deficits in adult vitamin D deficient BALB/c mice
Groves, Natalie J. and Burne, Thomas H. J. (2016). Sex-specific attentional deficits in adult vitamin D deficient BALB/c mice. Physiology and Behavior, 157, 94-101. doi: 10.1016/j.physbeh.2016.01.033
Gazibara, Tatjana, den Dekker, Herman T., de Jongste, Johan C., McGrath, John J., Eyles, Darryl W., Burne, Thomas H., Reiss, Irwin, Franco, Oscar H., Tiemeier, Henning, Jaddoe, Vincent W. V. and Duijts, Liesbeth (2016). Associations of maternal and fetal 25-hydroxyvitamin D levels with childhood lung function and asthma: the Generation R Study. Clinical and Experimental Allergy, 46 (2), 337-346. doi: 10.1111/cea.12645
Behavioural sensitisation to MK-801 is dose-dependent and independent of environmental context
Lefevre, Emilia M., Eyles, Darryl W. and Burne, Thomas H. J. (2016). Behavioural sensitisation to MK-801 is dose-dependent and independent of environmental context. Behavioural Brain Research, 298 (Part B), 241-245. doi: 10.1016/j.bbr.2015.11.014
The impact of vitamin D deficiency on behaviour and brain function in rodents
Overeem, Kathie, Eyles, Darryl W., McGrath, John J. and Burne, Thomas H. J. (2016). The impact of vitamin D deficiency on behaviour and brain function in rodents. Current Opinion in Behavioral Sciences, 7, 47-52. doi: 10.1016/j.cobeha.2015.11.012
Turner, Karly M., Peak, James and Burne, Thomas H. J. (2016). Measuring attention in rodents: comparison of a modified signal detection task and the 5-choice serial reaction time task. Frontiers in Behavioral Neuroscience, 9 (370) 370, 1-10. doi: 10.3389/fnbeh.2015.00370
Zhang, Christine R., Ho, Mei-Fong, Vega, Michelle C. Sanchez, Burne, Thomas H. J. and Chong, Suyinn (2015). Prenatal ethanol exposure alters adult hippocampal VGLUT2 expression with concomitant changes in promoter DNA methylation, H3K4 trimethylation and miR-467b-5p levels. Epigenetics and Chromatin, 8 (40) 40, 40. doi: 10.1186/s13072-015-0032-6
Vitamin D and the brain: key questions for future research
Cui, Xiaoying, Gooch, Helen, Groves, Natalie J., Sah, Pankaj, Burne, Thomas H., Eyles, Darryl W. and McGrath, John J. (2015). Vitamin D and the brain: key questions for future research. The Journal of Steroid Biochemistry and Molecular Biology, 148, 305-309. doi: 10.1016/j.jsbmb.2014.11.004
Vinkhuyzen, Anna A.E., Eyles, Darryl W., Burne, Thomas H., Blanken, Laura M.E., Kruithof, Claudia J., Verhulst, Frank, Jaddoe, Vincent W., Tiemeier, Henning and McGrath, John J. (2015). Prevalence and predictors of vitamin D deficiency based on maternal mid-gestation and neonatal cord bloods: the Generation R Study. Journal of Steroid Biochemistry And Molecular Biology, 164, 161-167. doi: 10.1016/j.jsbmb.2015.09.018
Peak, J. N., Turner, K. M. and Burne, T. H. J. (2015). The effect of developmental vitamin D deficiency in male and female Sprague-Dawley rats on decision-making using a rodent gambling task. Physiology and Behavior, 138, 319-324. doi: 10.1016/j.physbeh.2014.09.007
Vitamin D status during fetal life and childhood kidney outcomes
Miliku, K., Voortman, T., Franco, O. H., McGrath, J. J., Eyles, D. W., Burne, T. H., Hofman, A., Tiemeier, H. and Jaddoe, V. W. V. (2015). Vitamin D status during fetal life and childhood kidney outcomes. European Journal of Clinical Nutrition, 70 (5), 629-634. doi: 10.1038/ejcn.2015.216
Cui, Xiaoying, Lefevre, Emilia, Turner, Karly M., Coelho, Carlos M., Alexander, Suzy, Burne, Thomas H. J. and Eyles, Darryl W. (2014). MK-801-induced behavioural sensitisation alters dopamine release and turnover in rat prefrontal cortex. Psychopharmacology, 232 (3), 509-517. doi: 10.1007/s00213-014-3689-9
Cullen, Carlie L., Burne, Thomas H. J., Lavidis, Nickolas A. and Moritz, Karen M. (2014). Low dose prenatal alcohol exposure does not impair spatial learning and memory in two tests in adult and aged rats. PLoS One, 9 (6) e101482, e101482.1-e101482.9. doi: 10.1371/journal.pone.0101482
Turner, Karly M. and Burne, Thomas H. J. (2014). Comprehensive Behavioural Analysis of Long Evans and Sprague-Dawley Rats Reveals Differential Effects of Housing Conditions on Tests Relevant to Neuropsychiatric Disorders. PLoS One, 9 (3) e93411, e93411.1-e93411.10. doi: 10.1371/journal.pone.0093411
Burne, T. H. J., Alexander, S., Turner, K. M., Eyles, D. W. and McGrath, J. J. (2014). Developmentally vitamin D-deficient rats show enhanced prepulse inhibition after acute δ9-tetrahydrocannabinol. Behavioural Pharmacology, 25 (3), 236-244. doi: 10.1097/FBP.0000000000000041
Vitamin D as a neurosteroid affecting the developing and adult brain
Groves, Natalie J., McGrath, John J. and Burne, Thomas H. J. (2014). Vitamin D as a neurosteroid affecting the developing and adult brain. Annual Review of Nutrition, 34, 117-141. doi: 10.1146/annurev-nutr-071813-105557
Sanchez Vega, Michelle C., Chong, Suyinn and Burne, Thomas H. J. (2013). Early gestational exposure to moderate concentrations of ethanol alters adult behaviour in C57BL/6J mice. Behavioural Brain Research, 252, 326-333. doi: 10.1016/j.bbr.2013.06.003
The impact of adult vitamin D deficiency on behaviour and brain function in male Sprague-Dawley rats
Byrne, Jacqueline H., Voogt, Meggie, Turner, Karly M., Eyles, Darryl W., McGrath, John J. and Burne, Thomas H. J. (2013). The impact of adult vitamin D deficiency on behaviour and brain function in male Sprague-Dawley rats. PLoS ONE, 8 (8) e71593, e71593.1-e71593.14. doi: 10.1371/journal.pone.0071593
Kesby, James P., Cui, Xiaoying, Burne, Thomas H. J. and Eyles, Darryl W. (2013). Altered dopamine ontogeny in the developmentally vitamin D deficient rat and its relevance to schizophrenia. Frontiers in Cellular Neuroscience, 7 (111), 1-13. doi: 10.3389/fncel.2013.00111
Turner, Karly M. and Burne, Thomas H. J. (2013). Interaction of genotype and environment: effect of strain and housing conditions on cognitive behavior in rodent models of schizophrenia. Frontiers in Behavioral Neuroscience, 7 (JUL), 97. doi: 10.3389/fnbeh.2013.00097
Heterozygosity for Nuclear Factor One X Affects Hippocampal-Dependent Behaviour in Mice
Harris, Lachlan, Dixon, Chantelle, Cato, Kathleen, Heng, Yee Hsieh Evelyn, Kurniawan, Nyoman D., Ullmann, Jeremy F. P., Janke, Andrew L., Gronostajski, Richard M., Richards, Linda J., Burne, Thomas H. J. and Piper, Michael (2013). Heterozygosity for Nuclear Factor One X Affects Hippocampal-Dependent Behaviour in Mice. PLoS ONE, 8 (6) e65478, e65478. doi: 10.1371/journal.pone.0065478
Low vitamin D concentration exacerbates adult brain dysfunction
Cui, Xiaoying, Groves, Natalie J., Burne, Thomas H. J., Eyles, Darryl W. and McGrath, John J. (2013). Low vitamin D concentration exacerbates adult brain dysfunction. American Journal of Clinical Nutrition, 97 (5), 907-908. doi: 10.3945/ajcn.113.061176
Cui, X., Pelekanos, M., Liu, P-Y, Burne, T. H. J., McGrath, J. J. and Eyles, D. W. (2013). The vitamin D receptor in dopamine neurons; its presence in human substantia nigra and its ontogenesis in rat midbrain. Neuroscience, 236, 77-87. doi: 10.1016/j.neuroscience.2013.01.035
Cognitive performance and response inhibition in developmentally vitamin D (DVD)-deficient rats
Turner, Karly M., Young, Jared W., McGrath, John J., Eyles, Darryl W. and Burne, Thomas H. J. (2013). Cognitive performance and response inhibition in developmentally vitamin D (DVD)-deficient rats. Behavioural Brain Research, 242 (1), 47-53. doi: 10.1016/j.bbr.2012.12.029
Groves, Natalie J., Kesby, James P., Eyles, Darryl W., McGrath, John J., Mackay-Sim, Alan and Burne, Thomas H. J. (2013). Adult vitamin D deficiency leads to behavioural and brain neurochemical alterations in C57BL/6J and BALB/c mice. Behavioural Brain Research, 241 (1), 120-131. doi: 10.1016/j.bbr.2012.12.001
Lanham, S. A., Roberts, C., Habgood, A. K., Alexander, S., Burne, T. H. J., Eyles, D. W., Trueman, C. N., Cooper, M., McGrath, J. J. and Oreffo, R. O. C. (2013). Effect of vitamin D deficiency during pregnancy on offspring bone structure, composition and quality in later life. Journal of Developmental Origins of Health and Disease, 4 (1), 49-55. doi: 10.1017/S2040174412000542
Digital lecture recording: a cautionary tale
Johnston, Amy N. B., Massa, Helen and Burne, Thomas H. J. (2013). Digital lecture recording: a cautionary tale. Nurse Education in Practice, 13 (1), 40-47. doi: 10.1016/j.nepr.2012.07.004
Cullen, Carlie L., Burne, Thomas H. J., Lavidis, Nickolas A. and Moritz, Karen M. (2013). Low Dose Prenatal Ethanol Exposure Induces Anxiety-Like Behaviour and Alters Dendritic Morphology in the Basolateral Amygdala of Rat Offspring. PLoS One, 8 (1) e54924, e54924. doi: 10.1371/journal.pone.0054924
Eyles, Darryl, Burne, Thomas H. J. and McGrath, John J. (2013). Vitamin D, effects on brain development, adult brain function and the links between low levels of vitamin D and neuropsychiatric disease. Frontiers in Neuroendocrinology, 34 (1), 47-64. doi: 10.1016/j.yfrne.2012.07.001
Piper, Michael, Beneyto, Monica, Burne, Thomas H. J., Eyles, Darryl W., Lewis, David A. and McGrath, John J. (2012). The neurodevelopmental hypothesis of schizophrenia: Convergent clues from epidemiology and neuropathology. Psychiatric Clinics of North America, 35 (3), 571-584. doi: 10.1016/j.psc.2012.06.002
Formella, Isabel, Scott, Ethan, Burne, Thomas H.J., Lauren Harms, Liu, Pei-Yun, Karly Turner, Cui, Xiaoying and Eyles, Darryl (2012). Transient knockdown of tyrosine hydroxylase during development has persistent effects on behaviour in adult zebrafish (Danio rerio). PLoS ONE, 7 (8) e42482, e42482.1-e42482.8. doi: 10.1371/journal.pone.0042482
Harms, Lauren R., Cowin, Gary, Eyles, Darryl W., Kurniawan, Nyoman D., McGrath, John J. and Burne, Thomas H. J. (2012). Neuroanatomy and psychomimetic-induced locomotion in C57BL/6J and 129/X1SvJ mice exposed to developmental vitamin D deficiency. Behavioural Brain Research, 230 (1), 125-131. doi: 10.1016/j.bbr.2012.02.007
Attentional Processing in C57BL/6J Mice Exposed to Developmental Vitamin D Deficiency
Harms, Lauren R., Turner, Karly M., Eyles, Darryl W., Young, Jared W., McGrath, John J. and Burne, Thomas H. J. (2012). Attentional Processing in C57BL/6J Mice Exposed to Developmental Vitamin D Deficiency. PLoS One, 7 (4 Article No. ee35896) e35896, e35896. doi: 10.1371/journal.pone.0035896
Developmental vitamin D deficiency alters MK-801-induced behaviours in adult offspring
Kesby, James P., O'Loan, Jonathan C., Alexander, Suzanne, Deng, Chao, Huang, Xu-Feng, McGrath, John J., Eyles, Darryl W. and Burne, Thomas H. J. (2012). Developmental vitamin D deficiency alters MK-801-induced behaviours in adult offspring. Psychopharmacology, 220 (3), 455-463. doi: 10.1007/s00213-011-2492-0
The effects of vitamin D on brain development and adult brain function
James Kesby, Eyles, Darryl, Burne, Thomas H.J. and McGrath, John J. (2011). The effects of vitamin D on brain development and adult brain function. Molecular and Cellular Endocrinology, 347 (1-2), 121-127. doi: 10.1016/j.mce.2011.05.014
Do transmembrane domain neuregulin 1 mutant mice exhibit a reliable sensorimotor gating deficit?
Karl, T., Burne, T. H. J., van den Buuse, M. and Chesworth, R. (2011). Do transmembrane domain neuregulin 1 mutant mice exhibit a reliable sensorimotor gating deficit?. Behavioural Brain Research, 223 (2), 336-341. doi: 10.1016/j.bbr.2011.04.051
Increased de novo copy number variants in the offspring of older males
Flatscher-Bader, T., Foldi, C. J., Chong, S., Whitelaw, E., Moser, R. J., Burne, T. H. J., Eyles, D. W. and McGrath, J. J. (2011). Increased de novo copy number variants in the offspring of older males. Translational Psychiatry, 1 (Article # e34) e34, e34-e34. doi: 10.1038/tp.2011.30
Harms, Lauren R., Burne, Thomas H. J., Eyles, Darryl W. and McGrath, John J. (2011). Vitamin D and the brain. Best Practice and Research: Clinical Endocrinology and Metabolism, 25 (4), 657-669. doi: 10.1016/j.beem.2011.05.009
Vitamin D in fetal brain development
Eyles, Darryl, Burne, Thomas and McGrath, John (2011). Vitamin D in fetal brain development. Seminars in Cell and Developmental Biology, 22 (6), 629-636. doi: 10.1016/j.semcdb.2011.05.004
New perspectives on rodent models of advanced paternal age: Relevance to autism
Foldi, Claire J., Eyles, Darryl W., Flatscher-Bader, Traute, McGrath, John J. and Burne, Thomas H. J. (2011). New perspectives on rodent models of advanced paternal age: Relevance to autism. Frontiers in Behavioral Neuroscience, 5 (32), 1-7. doi: 10.3389/fnbeh.2011.00032
The Effects of breeding protocol in C57BL/6J mice on adult offspring behaviour
Foldi, Claire J., Eyles, Darryl W., McGrath, John J. and Burne, Thomas H. J. (2011). The Effects of breeding protocol in C57BL/6J mice on adult offspring behaviour. Plos One, 6 (3) e18152, e18152-1-e18152-7. doi: 10.1371/journal.pone.0018152
Burne, Thomas H.J., O'Loan, Jonathan, Splatt, Karisha, Alexander, Suzanne, McGrath, John J. and Eyles, Darryl (2011). Developmental vitamin D (DVD) deficiency alters pup retrieval but not isolation-induced pup ultrasonic vocalizations in the rat. Physiology and Behavior, 102 (2), 201-204. doi: 10.1016/j.physbeh.2010.11.006
Big ideas for small brains: What can psychiatry learn from worms, flies, bees and fish?
Burne, T. H. J., Scott, E., van Swinderen, B., Hilliard, M., Reinhard, J., Claudianos, C., Eyles, D. W. and McGrath, J. J. (2011). Big ideas for small brains: What can psychiatry learn from worms, flies, bees and fish?. Molecular Psychiatry, 16 (1), 7-16. doi: 10.1038/mp.2010.35
Cui Xiaoying, Pelekanos, Matthew, Burne, Thomas H.J., McGrath, John J. and Eyles, Darryl W. (2010). Maternal vitamin D deficiency alters the expression of genes involved in dopamine specification in the developing rat mesencephalon. Neuroscience Letters, 486 (3), 220-223. doi: 10.1016/j.neulet.2010.09.057
Developmental vitamin D deficiency and risk of schizophrenia: A 10-year update
McGrath, John J., Burne, Thomas H., Feron, Francois, Mackay-Sim, Allan and Eyles, Darryl W. (2010). Developmental vitamin D deficiency and risk of schizophrenia: A 10-year update. Schizophrenia Bulletin, 36 (6), 1073-1078. doi: 10.1093/schbul/sbq101
Neonatal vitamin D status and risk of schizophrenia: A population-based case-control study
McGrath, John J., Eyles, Darryl W., Pedersen, Carsten B., Anderson, Cameron, Ko, Pauline, Burne, Thomas H., Norgaard-Pedersen, Bent, Hougaard, David M. and Mortensen, Preben B. (2010). Neonatal vitamin D status and risk of schizophrenia: A population-based case-control study. Archives of General Psychiatry, 67 (9), 889-894. doi: 10.1001/archgenpsychiatry.2010.110
The utility of neonatal dried blood spots for the assessment of neonatal vitamin D status
Eyles, Darryl W., Morley, Ruth, Anderson, Cameron, Ko, Pauline, Burne, Thomas, Permezel, Michael, Mortensen, Preben B., Nørgaard-Pedersen, Bent, Hougaard, David M. and McGrath, John J. (2010). The utility of neonatal dried blood spots for the assessment of neonatal vitamin D status. Paediatric and Perinatal Epidemiology, 24 (3), 303-308. doi: 10.1111/j.1365-3016.2010.01105.x
Foldi, Claire J., Eyles, Darryl W., McGrath, John J. and Burne, Thomas H. J. (2010). Advanced paternal age is associated with alterations in discrete behavioural domains and cortical neuroanatomy of C57BL/6J mice. European Journal of Neuroscience, 31 (3), 556-564. doi: 10.1111/j.1460-9568.2010.07074.x
Effects of anesthetic agents on socially transmitted olfactory memories in mice
Burne, T. H. J., Johnston, A. N. B., Wilkinson, L. S. and Kendrick, K. M. (2010). Effects of anesthetic agents on socially transmitted olfactory memories in mice. Neurobiology of Learning and Memory, 93 (2), 268-274. doi: 10.1016/j.nlm.2009.10.007
Kesby, James P, Cui, Xiaoying, O'Loan, Jonathan, McGrath, John J, Burne, Thomas HJ and Eyles, Darryl W (2010). Developmental vitamin D deficiency alters dopamine-mediated behaviors and dopamine transporter function in adult female rats. Psychopharmacology, 208 (1), 159-168. doi: 10.1007/s00213-009-1717-y
Developmental vitamin D deficiency causes abnormal brain development
Eyles, Darryl, Cui, Xiaoying, Kesby, James, Harms, Lauren, Ko, Pauline, McGrath, John J. and Burne, Thomas H.J. (2009). Developmental vitamin D deficiency causes abnormal brain development. Psychoneuroendocrinology, 34 (Supplement 1), S247-S257. doi: 10.1016/j.psyneuen.2009.04.015
Developmental vitamin D deficiency alters dopamine turnover in neonatal rat forebrain
Kesby, James P., Cui, Xiaoying, Ko, Pauline, McGrath, John J., Burne, Thomas H. J. and Eyles, Darryl W. (2009). Developmental vitamin D deficiency alters dopamine turnover in neonatal rat forebrain. Neuroscience Letters, 461 (2), 155-158. doi: 10.1016/j.neulet.2009.05.070
Vitamin D and the Brain: A Neuropsychiatric Perspective
Harvey, Louise, Burne, Thomas, Cui, Xiaoying, Mackay-Sim, Alan, Eyles, Darryl and McGrath, John (2009). Vitamin D and the Brain: A Neuropsychiatric Perspective. Clinical Reviews in Bone and Mineral Metabolism, 7 (2), 199-205. doi: 10.1007/s12018-009-9031-0
Vitamin D and the brain: A neuropsychiatric perspective
Harvey, Louise, Burne, Thomas H. J., Cui, Xiaoying, Mackay-Sim, Alan, Eyles, Darryl and McGrath, John J. (2009). Vitamin D and the brain: A neuropsychiatric perspective. Clinical Reviews in Bone and Mineral Metabolism, 7 (2), 199-205. doi: 10.1007/s12018-009-9031-0
Saha, Sukanta, Barnett, Adrian G., Foldi, Claire, Burne, Thomas H., Eyles, Darryl W., Buka, Stephen L. and McGrath, John J. (2009). Advanced paternal age is associated with impaired neurocognitive outcomes during infancy and childhood. PLoS Medicine, 6 (3), 0303-0311. doi: 10.1371/journal.pmed.1000040
A sensitive LC/MS/MS assay of 25OH vitamin D₃ and 25OH vitamin D₂ in dried blood spots
Eyles, Darryl, Cameron Anderson, Ko, Pauline, Alun Jones, Andrew Thomas, Burne, Thomas H.J., Mortensen, Preban, Bo, Norgaard-Pedersen, Bent, Hougaard, David, Michael and McGrath, John J. (2009). A sensitive LC/MS/MS assay of 25OH vitamin D₃ and 25OH vitamin D₂ in dried blood spots. Clinica Chimica Acta, 403 (1-2), 145-151. doi: 10.1016/j.cca.2009.02.005
The p75 neurotrophin receptor regulates hippocampal neurogenesis and related behaviours
Catts, Vibeke, Al-Minhali, Noura, Burne, Thomas H.J., Colditz, Michael and Coulson, Elizabeth (2008). The p75 neurotrophin receptor regulates hippocampal neurogenesis and related behaviours. European Journal of Neuroscience, 28 (5), 883-892. doi: 10.1111/j.1460-9568.2008.06390.x
Olfactory mucosa is a potential source for autologous stem cell therapy for Parkinson's disease
Murrell, Wayne, Wetzig, Andrew, Donnellan, Michael, Féron, François, Burne, Tom, Meedeniya, Adrian, Kesby, James, Bianco, John, Perry, Chris, Silburn, Peter and Mackay-Sim, Alan (2008). Olfactory mucosa is a potential source for autologous stem cell therapy for Parkinson's disease. Stem Cells, 26 (8), 2183-2192. doi: 10.1634/stemcells.2008-0074
Protein expression in the nucleus accumbens of rats exposed to developmental vitamin D deficiency
McGrath, John, Iwazaki, Takeshi, Eyles, Darryl, Burne, Thomas, Cui, Xiaoying, Ko, Pauline and Matsumoto, Izuru (2008). Protein expression in the nucleus accumbens of rats exposed to developmental vitamin D deficiency. PLoS One, 3 (6) e2383, e2383. doi: 10.1371/journal.pone.0002383
Han, Mei, Deng, Chao, Burne, Thomas H.J., Newell, Kelly A. and Huang, Xu-Feng F. (2008). Short- and long-term effects of antipsychotic drug treatment on weight gain and H1 receptor expression. Psychoneuroendocrinology, 33 (5), 569-580. doi: 10.1016/j.psyneuen.2008.01.018
Johnston, Amy N. and Burne, Thomas H.J. (2008). Aposematic colouration enhances memory formation in domestic chicks trained in a weak passive avoidance learning paradigm. Brain Research Bulletin, 76 (3), 313-316. doi: 10.1016/j.brainresbull.2008.02.016
Developmental vitamin D deficiency alters adult behavior in 129/SvJ and C57BL/6J mice
Harms, Lauren R., Eyles, Darryl W., McGrath, John J., Mackay-Sim, Alan and Burne, Thomas H. J. (2008). Developmental vitamin D deficiency alters adult behavior in 129/SvJ and C57BL/6J mice. Behavioural Brain Research, 187 (2), 343-350. doi: 10.1016/j.bbr.2007.09.032
Burne, Thomas H. J., Eyles, Darryl and McGrath, John J. (2008). Animal models may help fractionate shared and discrete pathways underpinning schizophrenia and autism (Open Peer Commentary). Behavioral And Brain Sciences, 31 (3), 264-265. doi: 10.1017/S0140525X08004251
Abubaker, Roohi, Alaerts, Maaike, Allman, Ava-Ann, Barnett, Jennifer, Belujon, Pauline, Bittner, Robert A., Burne, Thomas H.J., Cahn, Wiepke, Chance, Steven, Cherkerzian, Sara, deSouza, Renan, Di Forti, Marta, du Bois, Teresa, Fatjo-Vilas, Mar, Green, Melissa, Halpern, Demian, John, John P., Kemp, Aaron, Koelkebeck, Katja, Lee, Jimmy, Lodge, Daniel J., Michalopoulou, Panayiota, Mompremier, LaNina, Nelson, Barnaby, Perala, Jonna, Rotarska-Jagiela, Anna, Schoeman, Renata, Thakkar, Katherine N., Valuri, Giuletta ... DeLisi, Lynn E. (2008). Summary of the 1st Schizophrenia International Research Society Conference oral sessions, Venice, Italy, June 21-25, 2008: the rapporteur reports. Schizophrenia Research, 105 (1-3), 289-383. doi: 10.1016/j.schres.2008.08.015
McGrath, John, Barnett, Adrian, Eyles, Darryl, Burne, Thomas, Pedersen, Carsten B. and Mortensen, Preben Bo (2007). The impact of nonlinear exposure-risk relationships on seasonal time-series data: modelling Danish neonatal birth anthropometric data. BMC Medical Research Methodology, 7 (1) 45, Article Number: 45. doi: 10.1186/1471-2288-7-45
Maternal vitamin D depletion alters neurogenesis in the developing rat brain
Cui, X. Y., McGrath, J. J., Burne, T. H. J., Mackay-Sim, A. and Eyles, D. W. (2007). Maternal vitamin D depletion alters neurogenesis in the developing rat brain. International Journal of Developmental Neuroscience, 25 (4), 227-232. doi: 10.1016/j.ijdevneu.2007.03.006
McGrath, J. J., Scragg, R., Chant, D. C., Eyles, D., Burne, T. H. J. and Obradovic, D. (2007). No association between serum 25-Hydroxyvitamin D3 level and performance on psychometric tests in NHANes III. Neuroepidemiology, 29 (1-2), 49-54. doi: 10.1159/000108918
O'Loan, Jonathan, Eyles, Darryl W., Kesby, James, Ko, Pauline, McGrath, John J. and Burne, Thomas H. J. (2007). Vitamin D deficiency during various stages of pregnancy in the rat: Its impact on development and behavior in adult offspring. Psychoneuroendocrinology, 32 (3), 227-234. doi: 10.1016/j.psyneuen.2006.12.006
Olfactory Ability in the Healthy Population: Reassessing Presbyosmia
Mackay-Sim, Alan, Johnston, Amy N. B., Owen, Caroline and Burne, Thomas H. J. (2006). Olfactory Ability in the Healthy Population: Reassessing Presbyosmia. Chemical Senses, 31 (8), 763-771. doi: 10.1093/chemse/bjl019
Effect of Y1 receptor deficiency on motor activity, exploration and anxiety
Karl, Tim, Burne, Thomas H. J. and Herzog, Herbert (2006). Effect of Y1 receptor deficiency on motor activity, exploration and anxiety. Behavioural Brain Research, 167 (1), 87-93. doi: 10.1016/j.bbr.2005.08.019
Eyles, D. W., Rogers, F., Buller, K., McGrath, J. J., Ko, P., French, K. and Burne, T. H. J. (2006). Developmental vitamin D (DVD) deficiency in the rat alters adult behaviour independently of HPA function. Psychoneuroendocrinology, 31 (8), 958-964. doi: 10.1016/j.psyneuen.2006.05.006
Kesby, James P., Burne, Thomas H.J., McGrath, John J. and Eyles, Darryl W. (2006). Developmental vitamin D deficiency alters MK 801-induced hyperlocomotion in the adult rat: An animal model of schizophrenia. Biological Psychiatry, 60 (6), 591-596. doi: 10.1016/j.biopsych.2006.02.033
Voltage gated calcium channels and vitamin D: exploring the convergent links between risk factors for schizophrenia
(2016–2019) NHMRC Project Grant
Delayed radial glial maturation linked to NFI deficiency as an underlying cause of cortical defects in humans and mice
(2016–2018) NHMRC Project Grant
Molecular control of adult neural stem cell quiescence. (2016-2018) Australian Research Council, Discovery Grant
Does adult vitamin D deficiency increase vulnerability to social stress resulting in altered brain function?
(2015–2017) NHMRC Project Grant
Adult vitamin D deficiency and cognitive dysfunction in a mouse model
(2014–2017) NHMRC Project Grant
The Developmental vitamin D-deficiency animal model of schizophrenia: Critical window for intervention and optimal dose
(2014–2017) NHMRC Project Grant
Research Areas
- Neuropsychiatric diseases (e.g. schizophrenia)
- Vitamin D deficiency (DVD)
- Advanced paternal age and brain development
- Epidemiology
- Psychiatry
- Neuroanatomy
- Molecular biology
- Developmental biology
- Behavioural neuroscience
- Autism
