You can help progress our research
You don't have to be a scientist to get involved with QBI. We offer a range of opportunities for everyday people to connect and progress our research and discoveries.
The foundation for all of our work is the funding we receive through a range of sources, including philanthropic donations from our generous supporters. There are many ways to give to QBI: directly, through planned giving, or holding fundraising events that entertain or challenge supporters as they dig deep to help us better understand the brain.
We also offer opportunities for students to learn directly from our inspiring researchers through lab placements, and for community members to tour our facilities and attend events. Finally, you can give one of the greatest gifts of all by volunteering for studies to advance treatments and diagnostics for brain diseases and disorders.
How you can support us
What your donations fund
Through your support you are helping QBI solve the major neurological health challenges facing our community today
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World leading research
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Brightest scientific minds
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Solutions to global health challenges
Brain Research Endowment Fund
Find out more Donate to research
QBI’s Brain Research Endowment Fund supports scientists exploring the unknown, which will guide new research on finding cures for diseases or improving quality of life.
Community & school programs
Australian Brain Bee
The Australian Brain Bee Challenge (ABBC) is a competition for high school students in year 10 to learn about the brain and its functions, learn about neuroscience research, find out about careers in neuroscience and to dispel misconceptions about neurological and mental illnesses.
Participate in a research study
By being part of our human research studies you can make a valuable contribution to improving the lives of people living with brain disease and disorder.
Research in action
- 22 May 2019Professor Nancy Kanwisher
Department of Brain and Cognitive Sciences, McGovern Institute for Brain Research,
Massachusetts Institute of Technology, Cambridge, Massachusetts, USA
CJCADR research leaders
CJCADR research leaders
Emeritus Professor Perry Bartlett
Emeritus ProfessorQueensland Brain InstituteAffiliate of Clem Jones Centre for Ageing and Dementia ResearchClem Jones Centre for Ageing Dementia ResearchResearcher profile is public:0Supervisor:Body:Emeritus Professor Perry Bartlett: Neurogenic regulation of cognition
Professor Perry Bartlett’s laboratory is focussed on understanding the mechanisms that regulate the production and function of new neurons, generated from the resident population of stem/precursor cells in a region of the adult brain known as the hippocampus.
Associate Professor Victor Anggono
ARC Future Fellow - Group LeaderQueensland Brain InstituteAffiliate of Clem Jones Centre for Ageing and Dementia ResearchClem Jones Centre for Ageing Dementia ResearchResearcher profile is public:1Supervisor:Researcher biography:Victor Anggono received his PhD in 2007 from the University of Sydney and undertook his postdoctoral training at the Johns Hopkins University in Baltimore, USA. In 2012, Dr Anggono returned to Australia as an NHMRC CJ Martin Research Fellow and joined the Queensland Brain Institute at the University of Queensland, where he is currently a Senior Research Fellow and Group Leader at the Clem Jones Centre for Ageing Dementia Research. His research aims to understand the molecular mechanisms of synaptic vesicle and glutamate receptor trafficking in neurons, processes that are essential for synaptic transmission, plasticity, learning and memory, and how their dysregulations impact on the pathophysiology of neurodegenerative diseases and neuropsychiatric disorders. Dr Anggono has published in journals such as Nature Neuroscience, Neuron, The Proceedings of the National Academy of Sciences USA, Journal of Neuroscience and Cell Reports, and has attracted more than 1500 citations. For his works, Dr Anggono was awarded the Boomerang Award (Australian Society for Biochemistry and Molecular Biology, 2011), the Young Scientist Award (Federation of Asian and Oceanian Biochemists and Molecular Biologists, 2015), the Science to Art Award (NHMRC, 2015) and more recently the Young Investigator Award (Asian-Pacific Society for Neurochemistry, 2016).
Body:Associate Professor Victor Anggono: Synaptic neurobiology
Our research combines biochemical, molecular and cellular biology in both cell culture (primary neurons and cell lines) and mouse models. We utilise gene editing technology, cutting-edge microscopy, proteomics, next-generation sequencing and behavioural analyses in our study. We are particularly interested in understanding the complex neuronal signalling cascades through protein-protein interactions and post-translational modifications of key synaptic molecules.
Professor Elizabeth Coulson
Group Leader in Dementia Research, Clem Jones Centre for Ageing Dementia Research & Professor and Professorial Research FellowQueensland Brain InstituteHead of SchoolSchool Biomedical ScienceAffiliate of Clem Jones Centre for Ageing and Dementia ResearchClem Jones Centre for Ageing Dementia ResearchResearcher profile is public:1Supervisor:Researcher biography:Professor Elizabeth (Lizzie) Coulson did her undergraduate Honours degree at the University of Melbourne, majoring in Genetics and Biochemistry. Her PhD (1997) in the Department of Pathology, University of Melbourne, with Professor Colin Masters, was on the normal function of the amyloid precursor protein of Alzheimer's disease. Following a year at the ZMBH, University of Heidelberg, Germany, she pursued postdoctoral work studying neuronal cell death in neurodegeneration and development at the Walter and Eliza Hall Institute with Professor Perry Bartlett before being recruited in 2003 to the University of Queensland as a founding member of the Queensland Brain Institute. She was appointed Professor in 2015, joining the School of Biomedical Sciences and becoming Deputy Head of School in 2016/7 and 2019 and Head of School in 2020. She maintains a 20% Queensland Brain Institutes appointment and is a member of the Clem Jones Centre for Ageing Dementia Research.
Her Lab webpage is: Coulson Lab - Neurotrophin - School of Biomedical Sciences ...
Body:Professor Elizabeth Coulson: Neurotrophins in Alzheimer’s disease
The Coulson laboratory is investigating how and why certain neurons die in neurodegenerative diseases including Alzheimer’s disease (AD) and motor neuron disease (MND). Their work focusses on the p75 neurotrophin receptor (p75NTR) and its role in neuronal loss, particularly the nerve cell degeneration that occurs in cholinergic neurons in the brain and spinal cord.
Associate Professor Zhitao Hu
Honorary Associate ProfessorQueensland Brain InstituteResearcher profile is public:0Supervisor:Body:Associate Professor Zhitao Hu: Neurotransmitter release
The Hu group focusses on candidate genes to understand their functional importance in synapses.
Professor Massimo Hilliard
NHMRC Leadership Fellow - GLQueensland Brain InstituteAffiliate of Clem Jones Centre for Ageing and Dementia ResearchClem Jones Centre for Ageing Dementia ResearchResearcher profile is public:1Supervisor:Researcher biography:Queensland Brain Institute
Dr Massimo A. Hilliard received his PhD in Biological Chemistry and Molecular Biology in 2001 from the University of Naples, Italy. His experimental work, performed at the Institute of Genetics and Biophysics of the CNR (Italian National Council of Research), was aimed at understanding the neuronal and genetic basis of aversive taste behavior (bitter taste) in C. elegans.
During his first postdoc at the University of California, San Diego, using the Ca2+ indicator Cameleon he published the first direct visualisation of chemosensory activity in C. elegans neurons. In his second postdoctoral work at the University of California, San Francisco and at The Rockefeller University, he switched from neuronal function to neuronal development, focusing in particular on how neurons establish and orient their polarity with respect to extracellular cues.
From September 2007, he is at the Queensland Brain Institute where he established an independent laboratory.
Body:Professor Massimo Hilliard: Molecular and cellular neurobiology
The Hilliard laboratory is focused on understanding the molecular mechanisms that regulate neuronal development, maintenance and repair, using C. elegans as a model system. The group’s current research goals are: (1) how the axon, which is the longest of the neuronal processes, is subdivided into structurally and functionally different compartments, (2) how the axon maintains its structure and function over the lifetime of the organism, and (3) how the axon can be repaired when severing damage occurs.
Professor Frederic Meunier
Professor and Academic Senior Group/Unit Leader/SupervisorQueensland Brain InstituteAffiliate of Clem Jones Centre for Ageing and Dementia Research & Affiliate of Clem Jones Centre for Ageing and Dementia ResearchClem Jones Centre for Ageing Dementia ResearchResearcher profile is public:1Supervisor:Researcher biography:Professor Frederic Meunier obtained his Masters degree in Neurophysiology at the Paris XI University, France in 1992 and completed his Ph.D in Neurobiology at the CNRS in Gif-sur-Yvette, France in 1996. He was the recipient of a European Biotechnology Fellowship and went on to postgraduate work at the Department of Biochemistry at Imperial College (1997-1999) and at Cancer Research UK (2000-2002) in London, UK. After a short sabbatical at the LMB-MRC in Cambridge (UK), he became a group leader at the School of Biomedical Sciences at the University of Queensland (Australia) in 2003. He joined the Queensland Brain Institute of the University of Queensland in 2007 and obtained an NHMRC senior research fellowship in 2009 renewed in 2014 with promotion. He became Professor in 2014 at the Queensland Brain Institute and is currently part of the Centre for Ageing Dementia Research.
Body:Professor Frederic Meunier: Single Molecule Neuroscience Laboratory
The overall goal of our research is to determine how brain cells communicate and survive in health and disease. Our lab focuses on the molecular events that govern vesicular trafficking within presynaptic nerve terminals and neurosecretory cells. Our discoveries have led to a deep understanding of how secretory vesicles interact with the cortical actin network prior to fusing with the plasma membrane to release the neurotransmitter.
Selected recent publications
Visualizing endocytic recycling and trafficking in live neurons by subdiffractional tracking of internalized molecules
Joensuu, Merja, Martinez-Marmol, Ramon, Padmanabhan, Pranesh, Glass, Nick R., Durisic, Nela, Pelekanos, Matthew, Mollazade, Mahdie, Balistreri, Giuseppe, Amor, Rumelo, Cooper-White, Justin J., Goodhill, Geoffrey J. and Meunier, Frederic A. (2017) Nature Protocols, 12 12:2590-2622. doi:10.1038/nprot.2017.116In vivo single-molecule imaging of syntaxin1A reveals polyphosphoinositide- and activity-dependent trapping in presynaptic nanoclusters
Bademosi, Adekunle T., Lauwers, Elsa, Padmanabhan, Pranesh, Odierna, Lorenzo, Chai, Ye Jin, Papadopulos, Andreas, Goodhill, Geoffrey J., Verstreken, Patrik, Van Swinderen, Bruno and Meunier, Frederic A. (2017) Nature Communications, 8 . doi:10.1038/ncomms13660Subdiffractional tracking of internalized molecules reveals heterogeneous motion states of synaptic vesicles
Joensuu, Merja, Padmanabhan, Pranesh, Durisic, Nela, Bademosi, Adekunle T. D., Cooper-Williams, Elizabeth, Morrow, Isabel C., Harper, Callista B., Jung, WooRam, Parton, Robert G., Goodhill, Geoffrey J., Papadopulos, Andreas and Meunier, Frederic A. (2016) Journal of Cell Biology, 215 2: 277-292. doi:10.1083/jcb.201604001Flux of signalling endosomes undergoing axonal retrograde transport is encoded by presynaptic activity and TrkB
Wang, Tong, Martin, Sally, Nguyen, Tam H., Harper, Callista B., Gormal, Rachel S., Martinez-Marmol, Ramon, Karunanithi, Shanker, Coulson, Elizabeth J., Glass, Nick R., Cooper-White, Justin J., Van Swinderen, Bruno and Meunier, Frederic A. (2016) Nature Communications, 7 . doi:10.1038/ncomms12976The Munc18-1 domain 3a hinge-loop controls syntaxin-1A nanodomain assembly and engagement with the SNARE complex during secretory vesicle priming
Kasula, Ravikiran, Chai, Ye Jin, Bademosi, Adekunle T., Harper, Callista B., Gormal, Rachel S., Morrow, Isabel C., Hosy, Eric, Collins, Brett M., Choquet, Daniel, Papadopulos, Andreas and Meunier, Frederic A. (2016) The Journal of Cell Biology, 214 7: 847-858. doi:10.1083/jcb.201508118Munc18-1 is a molecular chaperone for α-synuclein, controlling its self-replicating aggregation
Chai, Ye Jin, Sierecki, Emma, Tomatis, Vanesa M., Gormal, Rachel S., Giles, Nichole, Morrow, Isabel C., Xia, Di, Götz, Jürgen, Parton, Robert G., Collins, Brett M., Gambin, Yann and Meunier, Frédéric A. (2016) The Journal of Cell Biology, 214 6: 705-718. doi:10.1083/jcb.201512016Profiling of free fatty acids using stable isotope tagging uncovers a role for saturated fatty acids in neuroexocytosis
Narayana, Vinod K., Tomatis, Vanesa M., Wang, Tong, Kvaskoff, David and Meunier, Frederic A. (2015) Cell Chemistry and Biology, 22 11: 1552-1561. doi:10.1016/j.chembiol.2015.09.010Control of autophagosome axonal retrograde flux by presynaptic activity unveiled using botulinum neurotoxin type A
Wang, Tong, Martin, Sally, Papadopulos, Andreas, Harper, Callista B., Mavlyutov, Timur A., Niranjan, Dhevahi, Glass, Nick R., Cooper-White, Justin J., Sibarita, Jean-Baptiste, Choquet, Daniel, Davletov, Bazbek and Meunier, Frederic A. (2015) Journal of Neuroscience, 35 15: 6179-6194. doi:10.1523/JNEUROSCI.3757-14.2015Activity-driven relaxation of the cortical actomyosin II network synchronizes Munc18-1-dependent neurosecretory vesicle docking
Papadopulos, Andreas, Gomez, Guillermo A., Martin, Sally, Jackson, Jade, Gormal, Rachel S., Keating, Damien J., Yap, Alpha S. and Meunier, Frederic A. (2015) Nature Communications, 6 6297: 1-11. doi:10.1038/ncomms7297An acto-myosin II constricting ring initiates the fission of activity-dependent bulk endosomes in neurosecretory cells
Gormal, Rachel S, Nguyen, Tam H, Martin, Sally, Papadopulos, Andreas and Meunier, Frederic A (2015) Journal of Neuroscience, 35 4: 1380-1389. doi:10.1523/JNEUROSCI.3228-14.2015Professor Peter Nestor
Professor in NeuroscienceQueensland Brain InstituteAffiliate of Clem Jones Centre for Ageing and Dementia ResearchClem Jones Centre for Ageing Dementia ResearchResearcher profile is public:1Supervisor:Researcher biography:Prof Nestor joined the Queensland Brain Institute in October/2017 and has a conjoint appointment as a cognitive neurologist at Mater Misericordiae Ltd (Mater Hospital).
His particular interests include understanding the earliest stages of Alzheimer's disease (i.e. before dementia is established); atypical forms of dementia with a particular focus on primary progressive aphasia and dementias related to Parkinson's and Lewy body diseases; and improving differential diagnosis between the major categories of neurodegenerative diseases.
He works on development of neuropsychological tests of cognition, both to accurately track change over time and improve diagnostic accuracy between the major diseases causing dementia. He also uses multi-modal imaging (magnetic resonance imaging [MRI] and positron emission tomography [PET]) to understand the sequence of events occurring in degenerative brain diseases (particularly Alzheimer's disease, frontotemporal dementia, Parkinson's disease, motor neuron disease [ALS], progressive supranuclear palsy [PSP] and corticobasal degeneration [CBD]) and identify novel biomarkers. A major focus of his is on developing novel approaches to MR imaging for single subject pathological diagnoses that can be exported into the everyday clinical setting; recent examples include diffusion tensor imaging to identify PSP and CBD (Sajjadi et al, 2013) and quantitative susceptibility mapping in Parkinson's disease (Acosta-Cabornero et al, 2013).
Body:Professor Peter Nestor: Cognitive neurology
Professor Nestor aims to relate the neuropsychological and behavioural profiles of degenerative dementias, such as Alzheimer's disease and frontotemporal dementia, to regional brain damage through neuroimaging (MRI and PET) and histopathological analysis. His particular interest is the pathological landscape of incipient dementia (so-called mild cognitive impairment).
Associate Professor Steven Zuryn
Affiliate of Clem Jones Centre for Ageing and Dementia ResearchClem Jones Centre for Ageing Dementia ResearchPrincipal Research Fellow, ARC FundedQueensland Brain InstituteResearcher profile is public:1Supervisor:Researcher biography:Dr Steven Zuryn is a molecular geneticist within the Queensland Brain Institute, The University of Queensland. After training as a PhD in genetics, he undertook postdoctoral reseach at the Institut Génétique Biologie Moléculaire Cellulaire (IGBMC) in Strasbourg, France. He now leads an international and diverse team of postdoctoral, PhD, Honours, and undergraduate investigators studying epigenetics and mitochondrial biology. His laboratory's work focuses on the role and impact of mitochondrial dysfunction in neurodegenerative diseases and is particularly fascinated with mutations that accumulate within the mitochondria's own genome during ageing. His research has been published in the high profile journals Science, Nature Cell Biology, and Nature Communications and has appeared in multiple mainstream media outlets. For his research, he has received multiple international prizes and fellowships, been awarded grants from the NHMRC and ARC as primary chief investigator and is generously supported as a fellow of the Stafford Fox Research Foundation. Steven is passionate about communicating the critical importance of fundamental scientific research as a long-term human endeavour.
Follow the Zuryn lab on Twitter: @zurynlab
Visit the Zuryn lab website.
Body:Dr Steven Zuryn: Epigenetics and Mitochondrial Biology Lab
The Zuryn lab uses cutting-edge molecular techniques in the highly successful genetic model organism C. elegans as well as human cell culture to understand the fundamental mechanisms that promote disease progression caused by mitochondrial dysfunction. Mitochondria harbour their own genome (mtDNA), which is prone to accumulating mutations as we age leading to dysfunction that may contribute to the progressive nature of neurodegenerative diseases.
Professor Gail Robinson
Professorial Research FellowQueensland Brain InstituteResearcher profile is public:1Supervisor:Researcher biography:Professor Gail Robinson holds a joint Queensland Brain Institute and the School of Psychology appointment. She has been a clinical neuropsychologist and researcher for ~25 years in Australia and in London (UK), where she spent 14 years at the dynamic and historic National Hospital of Neurology and Neurosurgery, Queen Square, London. In 2010, she transitioned from a clinical role to an academic position at The University of Queensland where was Director of the Clinical Neuropsychology Doctoral programme (2010-2018), taking up this lead role again in 2023. Her clinical research is focused on both theoretical questions about brain-behaviour relationships like the crucial mechanisms for the executive control of language, and clinical questions regarding cognitive assessment and management of various pathologies including neurodegenerative disorders, neurodevelopmental disorders, brain tumours and stroke. Professor Robinson has attracted internal and national funding; she Leads the Neuropsychology Core of a large-scale longitudinal and multidisciplinary NHMRC Dementia Team Research grant (Prospective Imaging Study of Ageing: Genes, Brain and Behaviour - PISA). She was the recipient of an ARC Discovery Early Career Researcher Award (DECRA) in 2012 and a NHMRC Boosting Dementia Research Leadership Fellowship in 2018 in which she has been focused on early neurocognitive diagnostic indicators for dementia.
Body:Professor Gail Robinson: Cognitive and clinical neuropsychology
The Robinson group's clinical research is focused on both theoretical questions about brain-behaviour relationships like the crucial mechanisms for the executive control of language, and clinical questions regarding cognitive assessment and management of various pathologies including neurodegenerative disorders, neurodevelopmental disorders, brain tumours and stroke.