Dehorter Publications

Lysine myristoylation mediates long-term potentiation via membrane enrichment of synaptic plasticity effectors.

Benjamin Matthews, Sevannah A. Steeves, Isaac O. Akefe, Noorya Yasmin Ahmed, Rachel S. Gormal, Nathalie Dehorter, Tristan P. Wallis, Frédéric A. Meunier. The EMBO Journal. 2025 Jun 17:1-26. doi: https://doi.org/10.1038/s44318-025-00484-3

Glutamine Transport via Neurotransmitter Transporter 4 (NTT4, SLC6A17) Maintains Presynaptic Glutamate Supply at Excitatory Synapses in the Central Nervous System.

Angela L. Nicoli, A. Shaam Al Abed, Sarah R. Hulme, Abhijit Das, Gregory Gauthier-Coles, Angelika Bröer, Sarojini Balkrishna, Gaetan Burgio, Nathalie Dehorter, Caroline D. Rae, Stefan Bröer, Brian Billups. bioRxiv. 2024. doi: https://doi.org/10.1101/2024.10.20.616835

Maladaptation of Memory Systems Impairs Dorsal CA1-Dependent Temporal Binding and Declarative Memory in The Cntnap2 Knockout Mouse Model of Autism.

Elise C. Rawlinson, Michael H. McCullough, Aline Marighetto, A. Shaam Al Abed, Nathalie Dehorter. bioRxiv. 2024. doi: https://doi.org/10.1101/2024.10.29.620866

Alpha-Synuclein Induced Immune Response Triggers Parkinson's Disease-Like Symptoms.

Rebekah G. Parkinson, Tony Xu, Jacob Martin, Zizheng Xian, Ilvana Ziko, Jessica A. Pettitt, Alexandre RCom-H’Cheo-Forgues, Rebecca Buckland, Sarah L. Gordon, Christopher Parish, Anne Brüstle, Nathalie Dehorter. bioRxiv. 2024. doi: doi.org/10.1101/2024.05.27.596130

Parvalbumin interneuron activity in autism underlies susceptibility to PTSD-like memory formation.

Alice Shaam Al Abed, Tiarne Vickie Allen, Noorya Yasmin Ahmed, Azza Sellami, Yovina Sontani, Elise Caitlin Rawlinson, Aline Marighetto, Aline Desmedt, and Nathalie Dehorter. iScience. 2024 Apr 16;27(5):109747. eCollection 2024 May 17. PMID: 38741709 PMCID: PMC11089364 DOI: 10.1016/j.isci.2024.109747

Prediction of m6A and m5C at single-molecule resolution reveals a transcriptome-wide co-occurrence of RNA modifications.

P. Acera Mateos, A. J. Sethi, A Ravindran, A. Srivastava, K. Woodward, S. Mahmud, M. Kanchi, M. Guarnacci, J. Xu, Z. W. S. Yuen, Y. Zhou, A. Sneddon, W. Hamilton, J. Gao, L. M. Starrs, R. Hayashi, V. Wickramasinghe, K. Zarnack, T. Preiss, G Burgio, N. Dehorter, N. E. Shirokikh & E. Eyras. Nat Commun. 2024 May 9;15(1):3899. doi: 10.1038/s41467-024-47953-7. PMID: 38724548

Neuronal Replenishment via Hydrogel-Rationed Delivery of reprogramming Factors.

Negar Mahmoudi, Yi Wang, Niamh Moriarty, Noorya Y. Ahmed, Nathalie Dehorter, Leszek Lisowski, Alan R. Harvey, Clare L. Parish, Richard J. Williams, and David R. Nisbet. ACS Nano. 2024. 18, 4. doi: 10.1021/acsnano.3c11337

Developmental deficits of MGE-derived interneurons in the Cntnap2 knockout mouse model of autism spectrum disorder.

Noorya Yasmin Ahmed, Rhys Knowles, Lixinyu Liu, Yiming Yan, Xiaohan Li, Ulrike Schumann, Yumeng Wang, Yovina Sontani, Nathan Reynolds, Riccardo Natoli, Jiayu Wen, Isabel Del Pino, Da Mi, and Nathalie Dehorter. Frontiers in Cell and Developmental Biology. 2023. 11 1112062, 1-16. doi: 10.3389/fcell.2023.1112062

Developmental disruption of Erbb4 in Pet1+ neurons impairs serotonergic sub-system connectivity and memory formation.

Candela Barettino, Álvaro Ballesteros-Gonzalez, Andrés Aylón, Xavier Soler-Sanchis, Leticia Ortí, Selene Díaz, Isabel Reillo, Francisco García-García, Francisco José Iborra, Cary Lai, Nathalie Dehorter, Xavier Leinekugel, Nuria Flames, and Isabel Del Pino. Frontiers in Cell and Developmental Biology. 2021. 9 770458, 1-17. doi: 10.3389/fcell.2021.770458

From progenitors to progeny: shaping striatal circuit development and function.

Rhys Knowles, Nathalie Dehorter, and Tommas Ellender. The Journal of Neuroscience. 2021. 41 (46), 9483-9502. doi: 10.1523/JNEUROSCI.0620-21.2021

A second wave for the Neurokinin Tac2 pathway in brain research.

Shaam A. Al Abed, Nathan J. Reynolds, and Nathalie Dehorter. Biological Psychiatry. 2021. 90 (3), 156-164. doi: 10.1016/j.biopsych.2021.02.01

Er81 transcription factor fine-tunes striatal cholinergic interneuron activity and drives habit formation.

Noorya Yasmin Ahmed, Yadollah Ranjbar-Slamloo, Shaam Alice Al Abed, Lingxiao Gao, Yovina Sontani, Alexandre RCom-H'cheo-Gauthier, Ehsan Arabzadeh, and Nathalie Dehorter. The Journal of Neuroscience. 2021. 41 (20), 4392-4409. doi: 10.1523/JNEUROSCI.0967-20.2021

Shifting developmental trajectories during critical periods of brain formation.

Nathalie Dehorter and Isabel Del Pino. Frontiers in Cellular Neuroscience. 2020. 14 283, 1-14. doi: 10.3389/fncel.2020.00283

New insights into cholinergic neuron diversity.

Noorya Yasmin Ahmed, Rhys Knowles, and Nathalie Dehorter. Frontiers in Molecular Neuroscience. 2019. 12 204, 1-12. doi: 10.3389/fnmol.2019.00204

Loss of Cntnap2 causes axonal excitability deficits, developmental delay in cortical myelination, and abnormal stereotyped motor behavior.

Ricardo Scott, Alberto Sánchez-Aguilera, Kim Van Elst, Lynette Lim, Nathalie Dehorter, Sung Eun Bae, Giorgia Bartolini, Elior Peles, Martien J. H. Kas, Hilgo Bruining, and Oscar Marín. Cerebral Cortex. 2019. 29 (2), 586-597. doi: 10.1093/cercor/bhx341

Tuning neural circuits by turning the interneuron knob.

Nathalie Dehorter, Nicolás Marichal, Oscar Marín, and Benedikt Berninger. Current Opinion in Neurobiology. 2017. 42, 144-151. doi: 10.1016/j.conb.2016.12.009

Tuning of fast-spiking interneuron properties by an activity-dependent transcriptional switch.

Nathalie Dehorter, Gabriele Ciceri, Giorgia Bartolini, Lynette Lim, Isabel Del Pino, and Oscar Marín. Science. 2015. 349 (6253), 1216-1220. doi: 10.1126/science.aab3415