Researcher biography
Brett Collins is an NHMRC Career Development Fellow and head of the Molecular Trafficking Lab at UQ's Institute for Molecular Bioscience. He was a lead investigator in the seminal structural studies of AP2, the protein adaptor molecule central to clathrin-mediated endocytosis, and has since defined the molecular basis for the function of critical proteins regulating membrane trafficking and signalling at the endosome organelle. His team is now focused on understanding how discrete molecular interactions between proteins and lipids control these processes in human cells.
Associate Professor Collins was awarded his PhD in 2001 and has published over 75 papers including in Cell, Nature, Nature Structural and Molecular Biology, Developmental Cell, and The Proceedings of the National Academy of Sciences USA, altogether cited more than 3100 times. He is the recipient of 3 prestigious fellowships, including a previous Career Development Award from the National Health and Medical Research Council and a Future Fellowship from the Australian Research Council, and was awarded the University of Queensland Research Excellence Award in 2008. In 2015 he was awarded the Emerging Leader Award of the ANZSCDB and in 2016 the Merck Research Medal from the ASBMB. He is currently the President of the Queensland Protein Group.
Journal Articles
Morita, Yuki, Takegawa, Kaoru, Collins, Brett M. and Higuchi, Yujiro (2024). Polarity-dependent expression and localization of secretory glucoamylase mRNA in filamentous fungal cells. Microbiological Research, 282 127653, 127653. doi: 10.1016/j.micres.2024.127653
Weeratunga, Saroja, Gormal, Rachel S., Liu, Meihan, Eldershaw, Denaye, Livingstone, Emma K., Malapaka, Anusha, Wallis, Tristan P., Bademosi, Adekunle T., Jiang, Anmin, Healy, Michael D., Meunier, Frederic A. and Collins, Brett M. (2024). Interrogation and validation of the interactome of neuronal Munc18-interacting Mint proteins with AlphaFold2. Journal of Biological Chemistry, 300 (1) 105541, 105541. doi: 10.1016/j.jbc.2023.105541
Healy, Michael D. and Collins, Brett M. (2023). The PDLIM family of actin-associated proteins and their emerging role in membrane trafficking. Biochemical Society Transactions, 51 (6), 2005-2016. doi: 10.1042/bst20220804
Tan, Jing Zhi Anson, Jang, Se Eun, Batallas-Borja, Ana, Bhembre, Nishita, Chandra, Mintu, Zhang, Lingrui, Guo, Huimin, Ringuet, Mitchell T., Widagdo, Jocelyn, Collins, Brett M. and Anggono, Victor (2023). Copine-6 is a Ca2+ sensor for activity-induced AMPA receptor exocytosis. Cell Reports, 42 (12) 113460, 1-20. doi: 10.1016/j.celrep.2023.113460
Brooks, John W., Tillu, Vikas, Eckert, Julia, Verma, Suzie, Collins, Brett M., Parton, Robert G. and Yap, Alpha S. (2023). Caveola mechanotransduction reinforces the cortical cytoskeleton to promote epithelial resilience. Molecular Biology of the Cell, 34 (12) ar120, 1-14. doi: 10.1091/mbc.e23-05-0163
Morales-Paytuví, Frederic, Fajardo, Alba, Ruiz-Mirapeix, Carles, Rae, James, Tebar, Francesc, Bosch, Marta, Enrich, Carlos, Collins, Brett M., Parton, Robert G. and Pol, Albert (2023). Early proteostasis of caveolins synchronizes trafficking, degradation, and oligomerization to prevent toxic aggregation. Journal of Cell Biology, 222 (9) e202204020. doi: 10.1083/jcb.202204020
Joensuu, Merja, Syed, Parnayan, Saber, Saber H., Lanoue, Vanessa, Wallis, Tristan P., Rae, James, Blum, Ailisa, Gormal, Rachel S., Small, Christopher, Sanders, Shanley, Jiang, Anmin, Mahrhold, Stefan, Krez, Nadja, Cousin, Michael A., Cooper‐White, Ruby, Cooper‐White, Justin J., Collins, Brett M., Parton, Robert G., Balistreri, Giuseppe, Rummel, Andreas and Meunier, Frédéric A. (2023). Presynaptic targeting of botulinum neurotoxin type A requires a tripartite
PSG‐Syt1
‐
SV2
plasma membrane nanocluster for synaptic vesicle entry. The EMBO Journal, 42 (13) e112095, e112095. doi: 10.15252/embj.2022112095
Healy, Michael D., McNally, Kerrie E., Butkovič, Rebeka, Chilton, Molly, Kato, Kohji, Sacharz, Joanna, McConville, Calum, Moody, Edmund R. R., Shaw, Shrestha, Planelles-Herrero, Vicente J., Yadav, Sathish K. N., Ross, Jennifer, Borucu, Ufuk, Palmer, Catherine S., Chen, Kai-En, Croll, Tristan I., Hall, Ryan J., Caruana, Nikeisha J., Ghai, Rajesh, Nguyen, Thi H. D., Heesom, Kate J., Saitoh, Shinji, Berger, Imre, Schaffitzel, Christiane, Williams, Tom A., Stroud, David A., Derivery, Emmanuel, Collins, Brett M. and Cullen, Peter J. (2023). Structure of the endosomal Commander complex linked to Ritscher-Schinzel syndrome. Cell, 186 (10), 2219-2237.e29. doi: 10.1016/j.cell.2023.04.003
Nguyen‐Dien, Giang Thanh, Kozul, Keri‐Lyn, Cui, Yi, Townsend, Brendan, Kulkarni, Prajakta Gosavi, Ooi, Soo Siang, Marzio, Antonio, Carrodus, Nissa, Zuryn, Steven, Pagano, Michele, Parton, Robert G, Lazarou, Michael, Millard, S Sean, Taylor, Robert W, Collins, Brett M, Jones, Mathew JK and Pagan, Julia K (2023). FBXL4
suppresses mitophagy by restricting the accumulation of
NIX
and
BNIP3
mitophagy receptors. The EMBO Journal, 42 (13) e112767, e112767. doi: 10.15252/embj.2022112767
Healy, Michael D., Sacharz, Joanna, McNally, Kerrie E., McConville, Calum, Tillu, Vikas A., Hall, Ryan J., Chilton, Molly, Cullen, Peter J., Mobli, Mehdi, Ghai, Rajesh, Stroud, David A. and Collins, Brett M. (2022). Proteomic identification and structural basis for the interaction between sorting nexin SNX17 and PDLIM family proteins. Structure, 30 (12), 1590-1602.e6. doi: 10.1016/j.str.2022.10.001
Simonetti, Boris, Daly, James L., Simón-Gracia, Lorena, Klein, Katja, Weeratunga, Saroja, Antón-Plágaro, Carlos, Tobi, Allan, Hodgson, Lorna, Lewis, Philip A., Heesom, Kate J., Shoemark, Deborah K., Davidson, Andrew D., Collins, Brett M., Teesalu, Tambet, Yamauchi, Yohei and Cullen, Peter J. (2022). ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1. Proceedings of the National Academy of Sciences, 119 (25) e2201980119, 1-11. doi: 10.1073/pnas.2201980119
Parton, Robert G. and Collins, Brett M. (2022). The structure of caveolin finally takes shape. Science Advances, 8 (19) eabq6985, eabq6985. doi: 10.1126/sciadv.abq6985
Simonetti, Boris, Guo, Qian, Giménez-Andrés, Manuel, Chen, Kai-En, Moody, Edmund R. R., Evans, Ashley J., Chandra, Mintu, Danson, Chris M., Williams, Tom A., Collins, Brett M. and Cullen, Peter J. (2022). SNX27–Retromer directly binds ESCPE-1 to transfer cargo proteins during endosomal recycling. PLoS Biology, 20 (4) e3001601, e3001601. doi: 10.1371/journal.pbio.3001601
Paul, Blessy, Weeratunga, Saroja, Tillu, Vikas A., Hariri, Hanaa, Henne, W. Mike and Collins, Brett M. (2022). Structural predictions of the SNX-RGS proteins suggest they belong to a new class of lipid transfer proteins. Frontiers in Cell and Developmental Biology, 10 826688, 826688. doi: 10.3389/fcell.2022.826688
Wu, Yue, Cui, Zhenling, Huang, Yen-Hua, de Veer, Simon J., Aralov, Andrey V., Guo, Zhong, Moradi, Shayli V., Hinton, Alexandra O., Deuis, Jennifer R., Guo, Shaodong, Chen, Kai-En, Collins, Brett M., Vetter, Irina, Herzig, Volker, Jones, Alun, Cooper, Matthew A., King, Glenn F., Craik, David J., Alexandrov, Kirill and Mureev, Sergey (2022). Towards a generic prototyping approach for therapeutically-relevant peptides and proteins in a cell-free translation system. Nature Communications, 13 (1) 260, 260. doi: 10.1038/s41467-021-27854-9
Chandra, Mintu, Collins, Brett M. and Jackson, Lauren P. (2022). Biochemical basis for an interaction between SNX27 and the flexible SNX1 N-terminus. Advances in Biological Regulation, 83 100842, 1-9. doi: 10.1016/j.jbior.2021.100842
Chen, Kai-En, Guo, Qian, Hill, Timothy A., Cui, Yi, Kendall, Amy K., Yang, Zhe, Hall, Ryan J., Healy, Michael D., Sacharz, Joanna, Norwood, Suzanne J., Fonseka, Sachini, Xie, Boyang, Reid, Robert C., Leneva, Natalya, Parton, Robert G., Ghai, Rajesh, Stroud, David A., Fairlie, David P, Suga, Hiroaki, Jackson, Lauren P., Teasdale, Rohan D., Passioura, Toby and Collins, Brett M. (2021). De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex. Science Advances, 7 (49) eabg4007, eabg4007. doi: 10.1126/sciadv.abg4007
Yin, Huawu, Zhou, Xiuman, Huang, Yen-Hua, King, Gordon J., Collins, Brett M., Gao, Yanfeng, Craik, David J. and Wang, Conan K. (2021). Rational design of potent peptide inhibitors of the PD-1:PD-L1 interaction for cancer immunotherapy. Journal of the American Chemical Society, 143 (44) jacs.1c08132, 18536-18547. doi: 10.1021/jacs.1c08132
Lo, Harriet P., Lim, Ye-Wheen, Xiong, Zherui, Martel, Nick, Ferguson, Charles, Ariotti, Nicholas, Giacomotto, Jean, Rae, James, Floetenmeyer, Matthias, Moradi, Shayli Varasteh, Gao, Ya, Tillu, Vikas A., Xia, Di, Wang, Huang, Rahnama, Samira, Nixon, Susan J., Bastiani, Michele, Day, Ryan D., Smith, Kelly A., Palpant, Nathan J., Johnston, Wayne A., Alexandrov, Kirill, Collins, Brett M., Hall, Thomas E. and Parton, Robert G. (2021). Cavin4 interacts with Bin1 to promote T-tubule formation and stability in developing skeletal muscle. Journal of Cell Biology, 220 (12) e201905065. doi: 10.1083/jcb.201905065
Huang, Yen-Hua, Du, Qingdan, Jiang, Zhihao, King, Gordon J., Collins, Brett M., Wang, Conan K. and Craik, David J. (2021). Enabling efficient folding and high-resolution crystallographic analysis of bracelet cyclotides. Molecules, 26 (18) 5554. doi: 10.3390/molecules26185554
Parton, Robert G., Tillu, Vikas, McMahon, Kerrie-Ann and Collins, Brett M. (2021). Key phases in the formation of caveolae. Current Opinion in Cell Biology, 71, 7-14. doi: 10.1016/j.ceb.2021.01.009
Sharma, Gagan, Braga, Carolyne B., Chen, Kai-En, Jia, Xinying, Ramanujam, Venkatraman, Collins, Brett M., Rittner, Roberto and Mobli, Mehdi (2021). Structural basis for the binding of the cancer targeting scorpion toxin, ClTx, to the vascular endothelia growth factor receptor neuropilin-1. Current Research in Structural Biology, 3, 179-186. doi: 10.1016/j.crstbi.2021.07.003
McMillan, Kirsty J., Banks, Paul J., Hellel, Francesca L. N., Carmichael, Ruth E., Clairfeuille, Thomas, Evans, Ashley J., Heesom, Kate J., Lewis, Philip, Collins, Brett M., Bashir, Zafar, Henley, Jeremy M., Wilkinson, Kevin and Cullen, Peter J. (2021). Sorting nexin-27 regulates AMPA receptor trafficking through the synaptic adhesion protein LRFN2. eLife, 10 e59432. doi: 10.7554/elife.59432
Yong, Xuan Ling Hilary, Zhang, Lingrui, Yang, Liming, Chen, Xiumin, Tan, Jing Zhi Anson, Yu, Xiaojun, Chandra, Mintu, Livingstone, Emma, Widagdo, Jocelyn, Vieira, Marta M., Roche, Katherine W., Lynch, Joseph W., Keramidas, Angelo, Collins, Brett M. and Anggono, Victor (2021). Regulation of NMDA receptor trafficking and gating by activity-dependent CaMKIIα phosphorylation of the GluN2A subunit. Cell Reports, 36 (1) 109338, 1-21. doi: 10.1016/j.celrep.2021.109338
Peleg, Yoav, Vincentelli, Renaud, Collins, Brett M., Chen, Kai-En, Livingstone, Emma K., Weeratunga, Saroja, Leneva, Natalya, Guo, Qian, Remans, Kim, Perez, Kathryn, Bjerga, Gro E K, Larsen, Øivind, Vaněk, Ondřej, Skořepa, Ondřej, Jacquemin, Sophie, Poterszman, Arnaud, Kjær, Svend, Christodoulou, Evangelos, Albeck, Shira, Dym, Orly, Ainbinder, Elena, Unger, Tamar, Schuetz, Anja, Matthes, Susann, Bader, Michael, de Marco, Ario, Storici, Paola, Semrau, Marta S., Stolt-Bergner, Peggy ... Fleishman, Sarel J. (2021). Community-wide experimental evaluation of the PROSS stability-design method. Journal of Molecular Biology, 433 (13) 166964, 166964. doi: 10.1016/j.jmb.2021.166964
Li, Lei, Liu, Haowen, Krout, Mia, Richmond, Janet E., Wang, Yu, Bai, Jihong, Weeratunga, Saroja, Collins, Brett M., Ventimiglia, Donovan, Yu, Yi, Xia, Jingyao, Tang, Jing, Liu, Jie and Hu, Zhitao (2021). A novel dual Ca2+ sensor system regulates Ca2+-dependent neurotransmitter release. Journal of Cell Biology, 220 (4) e202008121, 1-24. doi: 10.1083/jcb.202008121
Tillu, Vikas A., Rae, James, Gao, Ya, Ariotti, Nicholas, Floetenmeyer, Matthias, Kovtun, Oleksiy, McMahon, Kerrie-Ann, Chaudhary, Natasha, Parton, Robert G. and Collins, Brett M. (2021). Cavin1 intrinsically disordered domains are essential for fuzzy electrostatic interactions and caveola formation. Nature Communications, 12 (1) 931, 931. doi: 10.1038/s41467-021-21035-4
Zhou, Yong, Ariotti, Nicholas, Rae, James, Liang, Hong, Tillu, Vikas, Tee, Shern, Bastiani, Michele, Bademosi, Adekunle T., Collins, Brett M., Meunier, Frederic A., Hancock, John F. and Parton, Robert G. (2021). Caveolin-1 and cavin1 act synergistically to generate a unique lipid environment in caveolae. Journal of Cell Biology, 220 (3) e202005138. doi: 10.1083/jcb.202005138
Daly, James L., Simonetti, Boris, Klein, Katja, Chen, Kai-En, Williamson, Maia Kavanagh, Antón-Plágaro, Carlos, Shoemark, Deborah K., Simón-Gracia, Lorena, Bauer, Michael, Hollandi, Reka, Greber, Urs F., Horvath, Peter, Sessions, Richard B., Helenius, Ari, Hiscox, Julian A., Teesalu, Tambet, Matthews, David A., Davidson, Andrew D., Collins, Brett M., Cullen, Peter J. and Yamauchi, Yohei (2020). Neuropilin-1 is a host factor for SARS-CoV-2 infection. Science, 370 (6518), 861-865. doi: 10.1126/science.abd3072
Crawley-Snowdon, Harriet, Yang, Ji-Chun, Zaccai, Nathan R., Davis, Luther J., Wartosch, Lena, Herman, Emily K., Bright, Nicholas A., Swarbrick, James S., Collins, Brett M., Jackson, Lauren P., Seaman, Matthew N. J., Luzio, J. Paul, Dacks, Joel B., Neuhaus, David and Owen, David J. (2020). Mechanism and evolution of the Zn-fingernail required for interaction of VARP with VPS29. Nature Communications, 11 (1) 5031, 1-15. doi: 10.1038/s41467-020-18773-2
Mota Vieira, Marta, Nguyen, Thien A., Wu, Kunwei, Badger, John D., Collins, Brett M., Anggono, Victor, Lu, Wei and Roche, Katherine W. (2020). An epilepsy-associated GRIN2A rare variant disrupts CaMKIIα phosphorylation of GluN2A and NMDA receptor trafficking. Cell Reports, 32 (9) 108104, 108104. doi: 10.1016/j.celrep.2020.108104
Weeratunga, Saroja, Paul, Blessy and Collins, Brett M. (2020). Recognising the signals for endosomal trafficking. Current Opinion in Cell Biology, 65, 17-27. doi: 10.1016/j.ceb.2020.02.005
Tripathi, Aashutosh, Jain, Megha, Chandra, Mintu, Parveen, Sameena, Yadav, Rupali, Collins, Brett M., Maiti, Sankar and Datta, Sunando (2020). EhC2B, a C2 domain-containing protein, promotes erythrophagocytosis in Entamoeba histolytica via actin nucleation. PLOS Pathogens, 16 (5) e1008489, e1008489. doi: 10.1371/journal.ppat.1008489
Das Gupta, Kaustav, Shakespear, Melanie R., Curson, James E.B., Murthy, Ambika M.V., Iyer, Abishek, Hodson, Mark P., Ramnath, Divya, Tillu, Vikas A., von Pein, Jessica B., Reid, Robert C., Tunny, Kathryn, Hohenhaus, Daniel M., Moradi, Shayli Varasteh, Kelly, Gregory M., Kobayashi, Takumi, Gunter, Jennifer H., Stevenson, Alexander J., Xu, Weijun, Luo, Lin, Jones, Alun, Johnston, Wayne A., Blumenthal, Antje, Alexandrov, Kirill, Collins, Brett M., Stow, Jennifer L., Fairlie, David P. and Sweet, Matthew J. (2020). Class IIa histone deacetylases drive toll-like receptor-inducible glycolysis and macrophage inflammatory responses via pyruvate kinase M2. Cell Reports, 30 (8), 2712-2728.e8. doi: 10.1016/j.celrep.2020.02.007
Teo, Jessica L., Gomez, Guillermo A., Weeratunga, Saroja, Davies, Elizabeth M., Noordstra, Ivar, Budnar, Srikanth, Katsuno-Kambe, Hiroko, McGrath, Meagan J., Verma, Suzie, Tomatis, Vanesa, Acharya, Bipul R., Balasubramaniam, Lakshmi, Templin, Rachel M., McMahon, Kerrie-Ann, Lee, Yoke Seng, Ju, Robert J., Stebhens, Samantha J., Ladoux, Benoit, Mitchell, Christina A., Collins, Brett M., Parton, Robert G. and Yap, Alpha S. (2020). Caveolae control contractile tension for epithelia to eliminate tumor cells. Developmental Cell, 54 (1), 75-91.e7. doi: 10.1016/j.devcel.2020.05.002
Simonetti, Boris, Paul, Blessy, Chaudhari, Karina, Weeratunga, Saroja, Steinberg, Florian, Gorla, Madhavi, Heesom, Kate J., Bashaw, Greg J., Collins, Brett M. and Cullen, Peter J. (2019). Molecular identification of a BAR domain-containing coat complex for endosomal recycling of transmembrane proteins. Nature Cell Biology, 21 (10), 1219-1233. doi: 10.1038/s41556-019-0393-3
Ugrankar, Rupali, Bowerman, Jade, Hariri, Hanaa, Chandra, Mintu, Chen, Kevin, Bossanyi, Marie-France, Datta, Sanchari, Rogers, Sean, Eckert, Kaitlyn M., Vale, Gonçalo, Victoria, Alexia, Fresquez, Joseph, McDonald, Jeffrey G., Jean, Steve, Collins, Brett M. and Henne, W. Mike (2019). Drosophila snazarus regulates a lipid droplet population at plasma membrane-droplet contacts in adipocytes. Developmental Cell, 50 (5), 557-572.e5. doi: 10.1016/j.devcel.2019.07.021
Lanoue, Vanessa, Chai, Ye Jin, Brouillet, Julie Z., Weckhuysen, Sarah, Palmer, Elizabeth E., Collins, Brett M. and Meunier, Frederic A. (2019). STXBP1 encephalopathy: connecting neurodevelopmental disorders with α-synucleinopathies?. Neurology, 93 (3), 114-123. doi: 10.1212/WNL.0000000000007786
Monk, Ian R., Shaikh, Nausad, Begg, Stephanie L., Gajdiss, Mike, Sharkey, Liam K. R., Lee, Jean Y. H., Pidot, Sacha J., Seemann, Torsten, Kuiper, Michael, Winnen, Brit, Hvorup, Rikki, Collins, Brett M., Bierbaum, Gabriele, Udagedara, Saumya R., Morey, Jacqueline R., Pulyani, Neha, Howden, Benjamin P., Maher, Megan J., McDevitt, Christopher A., King, Glenn F. and Stinear, Timothy P. (2019). Zinc-binding to the cytoplasmic PAS domain regulates the essential WalK histidine kinase of Staphylococcus aureus. Nature Communications, 10 (1) 3067, 3067. doi: 10.1038/s41467-019-10932-4
Chen, Kai‐En, Healy, Michael D. and Collins, Brett M. (2019). Towards a molecular understanding of endosomal trafficking by Retromer and Retriever. Traffic, 20 (7) tra.12649, 465-478. doi: 10.1111/tra.12649
Milne, Michael R., Qian, Lei, Turnbull, Marion T., Kinna, Genevieve, Collins, Brett M., Teasdale, Rohan D. and Coulson, Elizabeth J. (2019). Downregulation of SNX27 expression does not exacerbate amyloidogenesis in the APP/PS1 Alzheimer's disease mouse model. Neurobiology of Aging, 77, 144-153. doi: 10.1016/j.neurobiolaging.2019.01.011
Zhang, Alan H., Edwards, Ingrid A., Mishra, Biswa P., Sharma, Gagan, Healy, Michael D., Elliott, Alysha, Blaskovich, Mark A. T., Cooper, Matthew A., Collins, Brett M., Jia, Xinying and Mobli, Mehdi (2019). Elucidating the lipid binding properties of membrane-active peptides using cyclised nanodiscs. Frontiers in Chemistry, 7 (MAR) 238, 238. doi: 10.3389/fchem.2019.00238
Chandra, Mintu, Chin, Yanni K.-Y., Mas, Caroline, Feathers, J. Ryan, Paul, Blessy, Datta, Sanchari, Chen, Kai-En, Jia, Xinying, Yang, Zhe, Norwood, Suzanne J., Mohanty, Biswaranjan, Bugarcic, Andrea, Teasdale, Rohan D., Henne, W. Mike, Mobli, Mehdi and Collins, Brett M. (2019). Classification of the human phox homology (PX) domains based on their phosphoinositide binding specificities. Nature Communications, 10 (1) 1528, 1528. doi: 10.1038/s41467-019-09355-y
Chen, Kai-En, Tillu, Vikas A., Chandra, Mintu and Collins, Brett M. (2018). Molecular basis for membrane recruitment by the PX and C2 domains of Class II Phosphoinositide 3-Kinase-C2α. Structure, 26 (12), 1612-1625.e4. doi: 10.1016/j.str.2018.08.010
Kovtun, Oleksiy, Leneva, Natalya, Bykov, Yury S., Ariotti, Nicholas, Teasdale, Rohan D., Schaffer, Miroslava, Engel, Benjamin D., Owen, David. J., Briggs, John A. G. and Collins, Brett M. (2018). Structure of the membrane-assembled retromer coat determined by cryo-electron tomography. Nature, 561 (7724), 561-+. doi: 10.1038/s41586-018-0526-z
Tillu, Vikas A., Lim, Ye-Wheen, Kovtun, Oleksiy, Mureev, Sergey, Ferguson, Charles, Bastiani, Michele, McMahon, Kerrie-Ann, Lo, Harriet P., Hall, Thomas E., Alexandrov, Kirill, Collins, Brett M. and Parton, Robert G. (2018). A variable undecad repeat domain in cavin1 regulates caveola formation and stability. EMBO Reports, 19 (9) e45775. doi: 10.15252/embr.201845775
Healy, Michael D., Hospenthal, Manuela K., Hall, Ryan J., Chandra, Mintu, Chilton, Molly, Tillu, Vikas, Chen, Kai-En, Celligoi, Dion J., McDonald, Fiona J., Cullen, Peter J., Lott, J. Shaun, Collins, Brett M. and Ghai, Rajesh (2018). Structural insights into the architecture and membrane interactions of the conserved COMMD proteins. eLife, 7 e35898. doi: 10.7554/elife.35898
Li, Lei, Liu, Haowen, Wang, Wei, Chandra, Mintu, Collins, Brett M. and Hu, Zhitao (2018). SNT-1 functions as the Ca2+ sensor for tonic and evoked neurotransmitter release in Caenorhabditis Elegans. The Journal of Neuroscience, 38 (23), 5313-5324. doi: 10.1523/JNEUROSCI.3097-17.2018
Tello-Lafoz, M., Rodríguez-Rodríguez, C., Kinna, G., Loo, L. S., Hong, W., Collins, B. M., Teasdale, R. D. and Mérida, I. (2017). SNX27 links DGKζ to the control of transcriptional and metabolic programs in T lymphocytes. Scientific Reports, 7 (1) 16361, 1-14. doi: 10.1038/s41598-017-16370-w
Christie, Michelle P., Hu, Shu-Hong, Whitten, Andrew E., Rehman, Asma, Jarrott, Russell J., King, Gordon J., Collins, Brett M. and Martin, Jennifer L. (2017). Revisiting interaction specificity reveals neuronal and adipocyte Munc18 membrane fusion regulatory proteins differ in their binding interactions with partner SNARE Syntaxins. PloS one, 12 (10) e0187302, 1-16. doi: 10.1371/journal.pone.0187302
McNally, Kerrie E., Faulkner, Rebecca, Steinberg, Florian, Gallon, Matthew, Ghai, Rajesh, Pim, David, Langton, Paul, Pearson, Neil, Danson, Chris M., Nägele, Heike, Morris, Lindsey L., Singla, Amika, Overlee, Brittany L., Heesom, Kate J., Sessions, Richard, Banks, Lawrence, Collins, Brett M., Berger, Imre, Billadeau, Daniel D., Burstein, Ezra and Cullen, Peter J. (2017). Retriever is a multiprotein complex for retromer-independent endosomal cargo recycling. Nature cell biology, 19 (10), 1214-1225. doi: 10.1038/ncb3610
Mamonova, Tatyana, Zhang, Qiangmin, Chandra, Mintu, Collins, Brett M., Sarfo, Edward, Bu, Zimei, Xiao, Kunhong, Bisello, Alessandro and Friedman, Peter A. (2017). Origins of PDZ binding specificity. A computational and experimental study using NHERF1 and the parathyroid hormone receptor. Biochemistry, 56 (20), 2584-2593. doi: 10.1021/acs.biochem.7b00078
Kasula, Ravikiran, Chai, Ye Jin, Bademosi, Adekunle T., Harper, Callista B., Gormal, Rachel S., Morrow, Isabel C., Hosy, Eric, Collins, Brett M., Choquet, Daniel, Papadopulos, Andreas and Meunier, Frederic A. (2016). The Munc18-1 domain 3a hinge-loop controls syntaxin-1A nanodomain assembly and engagement with the SNARE complex during secretory vesicle priming. The Journal of Cell Biology, 214 (7) 847, 847-858. doi: 10.1083/jcb.201508118
Clairfeuille, Thomas, Mas, Caroline, Chan, Audrey S. M., Yang, Zhe, Tello-Lafoz, Maria, Chandra, Mintu, Wigagdo, Jocelyn, Kerr, Markus, Blessy, Paul, Merida, Isabel, Teasdale, Rohan D., Pavlos, Nathan J., Anggono, Victor and Collins, Brett (2016). A molecular code for endosomal recycling of phosphorylated cargos by the SNX27–retromer complex. Nature Structural and Molecular Biology, 23 (10), 921-932. doi: 10.1038/nsmb.3290
Chai, Ye Jin, Sierecki, Emma, Tomatis, Vanesa M., Gormal, Rachel S., Giles, Nichole, Morrow, Isabel C., Xia, Di, Götz, Jürgen, Parton, Robert G., Collins, Brett M., Gambin, Yann and Meunier, Frédéric A. (2016). Munc18-1 is a molecular chaperone for α-synuclein, controlling its self-replicating aggregation. The Journal of Cell Biology, 214 (6) 705, 705-718. doi: 10.1083/jcb.201512016
Follett, Jordan, Bugarcic, Andrea, Yang, Zhe, Ariotti, Nicholas, Norwood, Suzanne J., Collins, Brett M., Parton, Robert G. and Teasdale, Rohan D. (2016). Parkinson disease-linked Vps35 R524W mutation impairs the endosomal association of retromer and induces α-synuclein aggregation. Journal of Biological Chemistry, 291 (35), 18283-18298. doi: 10.1074/jbc.M115.703157
McMillan, Kirsty J., Gallon, Matthew, Jellett, Adam P., Clairfeuille, Thomas, Tilley, Frances C., McGough, Ian, Danson, Chris M., Heesom, Kate J., Wilkinson, Kevin A., Collins, Brett M. and Cullen, Peter J. (2016). Atypical parkinsonism-associated retromer mutant alters endosomal sorting of specific cargo proteins. Journal of Cell Biology, 214 (4), 389-399. doi: 10.1083/jcb.201604057
Yang, Zhe, Hong, Lee Kian, Follett, Jordan, Wabitsch, Martin, Hamilton, Nicholas A., Collins, Brett, Bugarcic, Andrea and Teasdale, Rohan D. (2016). Functional characterization of retromer in GLUT4 storage vesicle formation and adipocyte differentiation. The FASEB Journal, 39 (3), 1037-1050. doi: 10.1096/fj.15-274704
Bugarcic, Andrea, Vetter, Irina, Chalmers, Silke, Kinna, Genevieve, Collins, Brett M. and Teasdale, Rohan D. (2015). Vps26B-retromer negatively regulates plasma membrane resensitization of PAR-2. Cell Biology International, 39 (11), 1299-1306. doi: 10.1002/cbin.10508
Tillu, Vikas A., Kovtun, Oleksiy, McMahon, Kerrie-Ann, Collins, Brett M. and Parton, Robert G. (2015). A phosphoinositide-binding cluster in cavin1 acts as a molecular sensor for cavin1 degradation. Molecular Biology of the Cell, 26 (20), 3561-3569. doi: 10.1091/mbc.E15-06-0359
Ariotti, Nicholas, Rae, James, Leneva, Natalya, Ferguson, Charles, Loo, Dorothy, Okano, Satomi, Hill, Michelle M., Walser, Piers, Collins, Brett M. and Parton, Robert G. (2015). Molecular characterization of caveolin-induced membrane curvature. Journal of Biological Chemistry, 290 (41), 24875-24890. doi: 10.1074/jbc.M115.644336
Kovtun, Oleksiy, Tillu, Vikas A., Ariotti, Nicholas, Parton, Robert G. and Collins, Brett M. (2015). Cavin family proteins and the assembly of caveolae. Journal of Cell Science, 128 (7), 1269-1278. doi: 10.1242/jcs.167866
Ghai, Rajesh, Tello-Lafoz, Maria, Norwood, Suzanne J., Yang, Zhe, Clairefeuille, Thomas, Teasdale, Rohan D., Mérida, Isabel and Collins, Brett M. (2015). Phosphoinositide binding by the SNX27 FERM domain regulates localisation at the immune synapse of activated T-cells. Journal of Cell Science, 128 (3), 553-565. doi: 10.1242/jcs.158204
King, Nathan P., Newton, Patrice, Schuelein, Ralf, Brown, Darren L., Petru, Marketa, Zarsky, Vojtech, Dolezal, Pavel, Luo, Lin, Bugarcic, Andrea, Stanley, Amanda C., Murray, Rachael Z., Collins, Brett M., Teasdale, Rohan D., Hartland, Elizabeth L. and Stow, Jennifer L. (2015). Soluble NSF attachment protein receptor molecular mimicry by a Legionella pneumophila Dot/Icm effector. Cellular Microbiology, 17 (6), 767-784. doi: 10.1111/cmi.12405
Archbold, Julia K., Whitten, Andrew E., Hu, Shu-Hong, Collins, Brett M. and Martin, Jennifer L. (2014). SNARE-ing the structures of Sec1/Munc18 proteins. Current Opinion in Structural Biology, 29, 44-51. doi: 10.1016/j.sbi.2014.09.003
Kovtun, Oleksiy, Tilu, Vikas A., Jung, WooRam, Leneva, Natalya, Ariotti, Nicholas, Chaudhary, Natasha, Mandyam, Ramya A., Ferguson, Charles, Morgan, Garry P., Johnston, Wayne A., Harrop, Stephen J., Alexandrov, Kirill, Parton, Robert G. and Collins, Brett M. (2014). Structural insights into the organization of the cavin membrane coat complex. Developmental Cell, 31 (4), 405-419. doi: 10.1016/j.devcel.2014.10.002
Mas, Caroline, Norwood, Suzanne J., Bugarcic, Andrea, Kinna, Genevieve, Leneva, Natalya, Kovtun, Oleksiy, Ghai, Rajesh, Yanez, Lorena E. Ona, Davis, Jasmine L., Teasdale, Rohan D. and Collins, Brett M. (2014). Structural basis for different phosphoinositide specificities of the PX domains of sorting nexins regulating G-protein signaling. Journal of Biological Chemistry, 289 (41), 28554-28568. doi: 10.1074/jbc.M114.595959
Martin, Sally, Papadopulos, Andreas, Tomatis, Vanesa M., Sierecki, Emma, Malintan, Nancy T., Gormal, Rachel S., Giles, Nichole, Johnston, Wayne A., Alexandrov, Kirill, Gambin, Yann, Collins, Brett M. and Meunier, Frederic A. (2014). Increased polyubiquitination and proteasomal degradation of a Munc18-1 disease-linked mutant causes temperature-sensitive defect in exocytosis. Cell Reports, 9 (1), 206-218. doi: 10.1016/j.celrep.2014.08.059
Teasdale, Rohan D. and Collins, Brett (2014). Little evidence that FAM65B belongs to the family of phox homology (PX) and bin/amphiphysin/rvs (BAR) domain-containing proteins. PNAS: Proceedings of the National Academy of Sciences of the United States of America, 111 (39), E4064-E4064. doi: 10.1073/pnas.1412755111
Gallon, Matthew, Clairfeuille, Thomas, Steinberg, Florian, Mas, Caroline, Ghai, Rajesh, Sessions, Richard B., Teasdale, Rohan D., Collins, Brett M. and Cullen, Peter J. (2014). A unique PDZ domain and arrestin-like fold interaction reveals mechanistic details of endocytic recycling by SNX27-retromer. Proceedings of the National Academy of Sciences of the United States of America, 111 (35), E3604-E3613. doi: 10.1073/pnas.1410552111
Luo, Lin, Wall, Adam A., Yeo, Jeremy C., Condon, Nicholas D., Norwood, Suzanne J., Schoenwaelder, Simone, Chen, Kaiwen W., Jackson, Shaun, Jenkins, Brendan J., Hartland, Elizabeth L., Schroder, Kate, Collins, Brett M., Sweet, Matthew J. and Stow, Jennifer L. (2014). Rab8a interacts directly with PI3Kγ to modulate TLR4-driven PI3K and mTOR signalling. Nature Communications, 5 (1) 4407, 4407.1-4407.13. doi: 10.1038/ncomms5407
Tello-Lafoz, María, Ghai, Rajesh, Collins, Brett and Mérida, Isabel (2014). A role for novel lipid interactions in the dynamic recruitment of SNX27 to the T-cell immune synapse. BioArchitecture, 4 (6), 215-220. doi: 10.1080/19490992.2015.1031950
Sierecki, Emma, Stevers, Loes M., Giles, Nichole, Polinkovsky, Mark E., Moustaqil, Mehdi, Mureev, Sergey, Johnston, Wayne A., Dahmer-Heath, Mareike, Skalamera, Duka, Gonda, Thomas J., Gabrielli, Brian, Collins, Brett M., Alexandrov, Kirill and Gambin, Yann (2014). Rapid mapping of interactions between human SNX-BAR proteins measured in vitro by AlphaScreen and single-molecule spectroscopy. Molecular and Cellular Proteomics, 13 (9), 2233-2245. doi: 10.1074/mcp.M113.037275
Jia, ZhiGuang, Ghai, Rajesh, Collins, Brett M. and Mark, Alan E. (2014). The recognition of membrane-bound PtdIns3P by PX domains. Proteins: structure, function, and bioinformatics, 82 (10), 2332-2342. doi: 10.1002/prot.24593
Follett, Jordan, Norwood, Suzanne J., Hamilton, Nicholas A., Mohan, Megha, Kovtun, Oleksiy, Tay, Stephanie, Yang, Zhe, Wood, Stephen A., Mellick, George D., Silburn, Peter A., Collins, Brett M., Bugarcic, Andrea and Teasdale, Rohan D. (2014). The Vps35 D620N mutation linked to Parkinson's disease disrupts the cargo sorting function of retromer. Traffic, 15 (2), 230-244. doi: 10.1111/tra.12136
Gambin, Yann, Ariotti, Nicholas, McMahon, Kerrie-Ann, Bastiani, Michele, Sierecki, Emma, Kovtun, Oleksiy, Polinkovsky, Mark E., Magenau, Astrid, Jung, WooRam, Okano, Satomi, Zhou, Yong, Leneva, Natalya, Mureev, Sergey, Johnston, Wayne, Gaus, Katharina, Hancock, John F., Collins, Brett M., Alexandrov, Kirill and Parton, Robert G. (2014). Single-molecule analysis reveals self assembly and nanoscale segregation of two distinct cavin subcomplexes on caveolae. eLIFE, 2014 (3) e01434, e01434.1-e01434.18. doi: 10.7554/eLife.01434
Ghai, Rajesh, Mobli, Mehdi and Collins, Brett M. (2014). Measuring interactions of FERM domain-containing sorting nexin proteins with endosomal lipids and cargo molecules. Methods in Enzymology, 534, 331-349. doi: 10.1016/B978-0-12-397926-1.00019-6
Rehman, Asma, Jarrott, Russell J., Whitten, Andrew E., King, Gordon J., Hu, Shu-Hong, Christie, Michelle P., Collins, Brett M. and Martin, Jennifer L. (2013). Milligram quantities of homogeneous recombinant full-length mouse Munc18c from Escherichia coli cultures. PloS One, 8 (12) e83499, e83499.1-e83499.12. doi: 10.1371/journal.pone.0083499
Martin, Sally, Tomatis, Vanesa M., Papadopulos, Andreas, Christie, Michelle P., Malintan, Nancy T., Gormal, Rachel S., Sugita, Shuzo, Martin, Jennifer L., Collins, Brett M. and Meunier, Frederic A. (2013). The Munc18-1 domain 3a loop is essential for neuroexocytosis but not for syntaxin-1A transport to the plasma membrane. Journal of Cell Science, 126 (11), 2353-2360. doi: 10.1242/jcs.126813
Ghai, Rajesh, Bugarcic, Andrea, Liu, Huadong, Norwood, Suzanne J., Skeldal, Sune, Coulson, Elizabeth J., Li, Shawn Shun-Cheng, Teasdale, Rohan D. and Collins, Brett M. (2013). Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins. Proceedings of the National Academy of Sciences of the United States of America, 110 (8), E643-E652. doi: 10.1073/pnas.1216229110
Mangold, Sabine, Norwood, Suzanne J., Yap, Alpha S and Collins, Brett M. (2012). The juxtamembrane domain of the E-cadherin cytoplasmic tail contributes to its interaction with Myosin VI. BioArchitecture, 2 (5), 185-188. doi: 10.4161/bioa.22082
Tnimov, Zakir, Guo, Zhong, Gambin, Yann, Nguyen, Uyen T. T., Wu, Yao-Wen, Abankwa, Daniel, Stigter, Anouk, Collins, Brett, Waldmann, Herbert, Goody, Roger, S. and Alexandrov, Kirill (2012). Quantitative analysis of prenylated RhoA interaction with its chaperone, RhoGDI. Journal of Biological Chemistry, 287 (32), 26549-26562. doi: 10.1074/jbc.M112.371294
Collins, Brett, Davis, Melissa, Hancock, John F. and Parton, Robert G. (2012). Structure-based reassessment of the caveolin signalling model: Do caveolae regulate signaling through caveolin-protein interactions. Developmental Cell, 23 (1), 11-20. doi: 10.1016/j.devcel.2012.06.012
Christie, Michelle P., Whitten, Andrew E., King, Gordon J., Hu, Shu-Hong, Jarrott, Russell J., Chen, Kai-En, Duff, Anthony P., Callow, Philip, Collins, Brett M., James, David E. and Martin, Jennifer L. (2012). Low-resolution solution structures of Munc18: Syntaxin protein complexes indicate an open binding mode driven by the Syntaxin N-peptide. Proceedings of the National Academy of Sciences of the United States of America, 109 (25), 9816-9821. doi: 10.1073/pnas.1116975109
Chhabra, Sandeep, Dolezal, Olan, Collins, Brett M., Newman, Janet, Simpson, Jamie S., Macreadie, Ian G., Fernley, Ross, Peat, Thomas S and Swarbrick, James D. (2012). Structure of S. aureus HPPK and the discovery of a new substrate site inhibitor. Plos One, 7 (1) e29444, e29444-1-e29444-16. doi: 10.1371/journal.pone.0029444
Teasdale, Rohan D. and Collins, Brett M. (2012). Insights into the PX (phox-homology) domain and SNX (sorting nexin) protein families: structures, functions and roles in disease. Biochemical Journal, 441 (Part 1), 39-59. doi: 10.1042/BJ20111226
Ghai, Rajesh, Falconer, Robert J. and Collins, Brett M. (2012). Applications of isothermal titration calorimetry in pure and applied research—survey of the literature from 2010. Journal of Molecular Recognition, 25 (1), 32-52. doi: 10.1002/jmr.1167
Bugarcic, Andrea, Yang, Zhe, Kerr, Markus C., Griffith, John Griffin, Collins, Brett M. and Teasdale, Rohan D. (2011). VPS26A and VPS26B subunits define distinct Retromer complexes. Traffic, 12 (12), 1759-1773. doi: 10.1111/j.1600-0854.2011.01284.x
Han, Gayoung A., Malintan, Nancy T., Saw, Ner Mu Nar, Li, Lijun, Han, Liping, Meunier, Frederic A., Collins, Brett M. and Sugita, Shuzo (2011). Munc18-1 domain-1 controls vesicle docking and secretion by interacting with syntaxin-1 and chaperoning it to the plasma membrane. Molecular Biology of The Cell, 22 (21), 4134-4149. doi: 10.1091/mbc.E11-02-0135
Ghai, Rajesh and Collins, Brett M. (2011). PX-FERM proteins: A link between endosomal trafficking and signaling?. Small GTPases, 2 (5), 259-263. doi: 10.4161/sgtp.2.5.17276
Offenhäuser, Carolin, Lei, Nazi, Roy, Sandrine, Collins, Brett M., Stow, Jennifer L. and Murray, Rachael Z. (2011). Syntaxin 11 binds Vti1b and regulates late endosome to lysosome fusion in macrophages. Traffic, 12 (6), 762-773. doi: 10.1111/j.1600-0854.2011.01189.x
Swarbrick, James D., Shaw, Daniel J., Chhabra, Sandeep, Ghai, Rajesh, Valkov, Eugene, Norwood, Suzanne, Seaman, Matthew N. J. and Collins, Brett M. (2011). VPS29 is not an active metallo-phosphatase but is a rigid scaffold required for retromer interaction with accessory proteins. PLoS One, 6 (5) e20420, e20420-1-e20420-15. doi: 10.1371/journal.pone.0020420
Ghai, Rajesh, Mobli, Mehdi, Norwood, Suzanne J., Bugarcic, Andrea, Teasdale, Rohan D., King, Glenn F. and Collins, Brett M. (2011). Phox homology band 4.1/ezrin/radixin/moesin-like proteins function as molecular scaffolds that interact with cargo receptors and Ras GTPases. Proceedings of the National Academy of Sciences of the United States of America, 108 (19), 7763-7768. doi: 10.1073/pnas.1017110108
Mangold, Sabine, Wu, Selwin K., Norwood, Suzanne J., Collins, Brett M., Hamilton, Nicholas A., Thorn, Peter and Yap, Alpha S. (2011). Hepatocyte growth factor acutely perturbs actin filament anchorage at the epithelial zonula adherens. Current Biology, 21 (6), 503-507. doi: 10.1016/j.cub.2011.02.018
Hu, Shu-Hong, Christie, Michelle P., Saez, Natalie J., Latham, Catherine F., Jarrott, Russell, Lua, Linda H. L., Collins, Brett M. and Martin, Jennifer L. (2011). Possible roles for Munc18-1 domain 3a and Syntaxin1 N-peptide and C-terminal anchor in SNARE complex formation. Proceedings of the National Academy of Sciences of the United States of America, 108 (3), 1040-1045. doi: 10.1073/pnas.0914906108
Falconer, Robert J. and Collins, Brett M. (2011). Survey of the year 2009: applications of isothermal titration calorimetry. Journal of Molecular Recognition, 24 (1), 1-16. doi: 10.1002/jmr.1073
Norwood, SJ, Shaw, DJ, Cowieson, NP, Owen, DJ, Teasdale, RD and Collins, BM (2011). Assembly and solution structure of the core retromer protein complex. Traffic, 12 (1), 56-71. doi: 10.1111/j.1600-0854.2010.01124.x
Kubala, MH, Kovtun, O, Alexandrov, K and Collins, BM (2010). Structural and thermodynamic analysis of the GFP:GFP-nanobody complex. Protein Science, 19 (12), 2389-2401. doi: 10.1002/pro.519
Drinkwater, Nyssa, Vu, Hoan, Lovell, Kimberly M., Criscione, Kevin R., Collins, Brett M., Prisinzano, Thomas E., Pulsen, Sally‑Ann, McLeish, Michael J., Grunewald, Gary L. and Martin, Jennifer L. (2010). Fragment-based screening by X-ray crystallography, MS and isothermal titration calorimetry to identify PNMT (phenylethanolamine N-methyltransferase) inhibitors. Biochemical Journal, 431 (1), 51-61. doi: 10.1042/BJ20100651
Han, GA, Malintan, NT, Collins, BM, Meunier, FA and Sugita, S (2010). Munc18-1 as a key regulator of neurosecretion. Journal of Neurochemistry, 115 (1), 1-10. doi: 10.1111/j.1471-4159.2010.06900.x
Falconer, RJ, Penkova, A, Jelesarov, I and Collins, BM (2010). Survey of the year 2008: Applications of isothermal titration calorimetry. Journal of Molecular Recognition, 23 (5), 395-413. doi: 10.1002/jmr.1025
Jackson, Lauren P., Kelly, Bernard T., McCoy, Airlie J., Gaffry, Thomas, James, Leo C., Collins, Brett M., Honing, Stefan, Evans, Philip R. and Owen, David J. (2010). A large-scale conformational change couples membrane recruitment to cargo binding in the AP2 clathrin adaptor complex. Cell, 141 (7), 1220-1229. doi: 10.1016/j.cell.2010.05.006
Owen, DJ and Collins, BM (2010). Vesicle transport: A new player in APP trafficking. Current Biology, 20 (9), R413-R415. doi: 10.1016/j.cub.2010.03.017
Han, Liping, Jiang, Tiandan, Han, Gayoung A., Malintan, Nancy T., Xie, Li., Wang, Li., Tse, Frederick W., Gaisano, Herbert Y., Collins, Brett M., Meunier, Frederic A. and Sugita, Shuzo (2009). Rescue of Munc18-1 and -2 double knockdown reveals the essential functions of interaction between Munc18 and closed syntaxin in PC12 cells. Molecular Biology of the Cell, 20 (23), 4962-4975. doi: 10.1091/mbc.E09-08-0712
Malintan, Nancy, Nguyen, Tam H, Han, Liping, Latham, Catherine F., Osborne, Shona L., Wen, Peter, Lim, Siew, Joo, Tiffany, Sugita, Shuzo, Collins, Brett M. and Meunier, Frederic A. (2009). Abrogating Munc18-1 SNARE complex interaction has limited impact on exocytosis in PC12 cells. The Journal of Biological Chemistry, 284 (32), 21637-21646. doi: 10.1074/jbc.M109.013508
Collins, B. M. (2008). The structure and function of the retrometer protein complex.. Traffic, 9 (11), 1811-1822. doi: 10.1111/j.1600-0854.2008.00777.x
Collins, Brett M., Norwood, Suzanne J., Kerr, Markus C., Mahony, Donna, Seaman, Matthew N. J. and Teasdale, Rohan D. (2008). Structure of Vps26B and Mapping of its Interaction with the Retromer Protein Complex. Traffic, 9 (3), 366-379. doi: 10.1111/j.1600-0854.2007.00688.x
Miller, Sharon E., Collins, Brett M., McCoy, Airlie J., Robinson, Margaret S. and Owen, David J. (2007). A SNARE-adaptor interaction is a new mode of cargo recognition in clathrin-coated vesicles. Nature, 450 (7169), 570-574. doi: 10.1038/nature06353
Edeling, Melissa A., Mishra, Sanjay K., Keyel, Peter A., Steinhauser, Amie L., Collins, Brett M., Roth, Robyn, Heuser, John E., Owen, David J. and Traub, Linton M. (2006). Molecular Switches Involving the AP-2 Beta 2 Appendage Regulate Endocytic Cargo Selection and Clathrin Coat Assembly. Developmental Cell, 10 (3), 329-342. doi: 10.1016/j.devcel.2006.01.016
Atreya, Anand R., Cattle, Bryan C., Collins, Brendan M., Essenburg, Benjamin, Franken, Gordon H., Saxe, Andrew M., Schiffres, Scott N. and Kornhauser, Alain L. (2006). Prospect Eleven: Princeton University's entry in the 2005 DARPA Grand Challenge. Journal of Field Robotics, 23 (9), 745-753. doi: 10.1002/rob.20141
Collins, Brett M., Skinner, Claire F., Watson, Peter J., Seaman, Matthew N. J. and Owen, David J. (2005). Vps29 has a phosphoesterase fold that acts as a protein interaction scaffold for retromer assembly. Nature Structural & Molecular Biology, 12 (7), 594-602. doi: 10.1038/nsmb954
Watson, Peter J., Frigerio, Gabriella, Collins, Brett M., Duden, Rainer and Owen, David J. (2004). gamma-COP appendage domain - Structure and function. Traffic, 5 (2), 79-88. doi: 10.1111/j.1600-0854.2004.00158.x
Owen, David J., Collins, Brett M. and Evans, Philip R. (2004). Adaptors for Clathrin Coats: Structure and Function. Annual Review of Cell And Developmental Biology, 20 (1), 153-191. doi: 10.1146/annurev.cellbio.20.010403.104543
Collins, Brett M., Praefcke, Gerrit J. K., Robinson, Margaret S. and Owen, David J. (2003). Structural basis for binding of accessory proteins by the appendage domain of GGAs. Nature Structural Biology, 10 (8), 607-613. doi: 10.1038/nsb955
Lui, Winnie W. Y., Collins, Brett M., Hirst, Jennifer, Motley, Alison, Millar, Caroline, Schu, Peter, Owen, David J. and Robinson, Margaret S. (2003). Binding partners for the COOH-Terminal appendage domains of the GGAs and gamma-adaptin. Molecular Biology of The Cell, 14 (6), 2385-2398. doi: 10.1091/mbc.E02-11-0735
Collins, Brett M., Cubeddu, Liza, Naidoo, Nishen, Harrop, Stephen J., Kornfeld, Geoff D., Dawes, Ian W., Curmi, Paul M. G. and Mabbutt, Bridget C. (2003). Homomeric ring assemblies of eukaryotic Sm proteins have affinity for both RNA and DNA - Crystal structure of an oligomeric complex of yeast SmF. Journal of Biological Chemistry, 278 (19), 17291-17298. doi: 10.1074/jbc.M211826200
Collins, Brett M., Watson, Peter J. and Owen, David J. (2003). The structure of the GGA1-GAT domain reveals the molecular basis for ARF binding and membrane association of GGAs. Developmental Cell, 4 (3), 321-332. doi: 10.1016/S1534-5807(03)00037-6
Collins, Brett M., McCoy, Airlie J., Kent, Helen M., Evans, Philip R. and Owen, David J. (2002). Molecular architecture and functional model of the endocytic AP2 complex. Cell, 109 (4), 523-535. doi: 10.1016/S0092-8674(02)00735-3
Collins, B. M., Harrop, S. J., Kornfeld, G. D., Dawes, I. W., Curmi, P. M. G. and Mabbutt, B. C. (2001). Crystal structure of a heptameric Sm-like protein complex from archaea: Implications for the structure and evolution of snRNPs. Journal of Molecular Biology, 309 (4), 915-923. doi: 10.1006/jmbi.2001.4693
Corthals, GL, Collins, BM, Mabbutt, BC, Williams, KL and Gooley, AA (1997). Purification by reflux electrophoresis of whey proteins and of a recombinant protein expressed in Dictyostelium discoideum. Journal of Chromatography A, 773 (1-2), 299-309. doi: 10.1016/S0021-9673(97)00237-9
Conference Papers
Livingstone, Emma, Whitten, Andrew, Weeratunga, Saroja, Martin, Jennifer and Collins, Brett (2018). Characterisation of protein complexes essential to cellular trafficking. 32nd Annual Symposium of the Protein Society, Boston, MA, 9-12 July 2018 . Hoboken, NJ, United States: Wiley-Blackwell.
Paul, B., Kim, H. S., Kerr, M. C., Huston, W. M., Teasdale, R. D. and Collins, B. M. (2017). Structural basis for the hijacking of endosomal sorting nexin proteins by Chlamydia trachomatis. Annual Joint Meeting of the American Society for Cell Biology and the European Molecular Biology Organization (ASCB/EMBO), Philadelphia, PA United States, 2-6 December 2017. Bethesda, MD United States: American Society for Cell Biology.
Teasdale, R., Follett, J., Bugarcic, A., Yang, Z. and Collins, B. (2015). Parkinson-associated VPS35 mutations alter retromer cellular functions. 25th Biennial Meeting of the International Society for Neurochemistry Jointly with the 13th Meeting of the Asian Pacific Society for Neurochemistry in Conjunction with the 35th Meeting of the Australasian Neuroscience Society, Cairns, QLD Australia Conference, 23-27 August 2015. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/jnc.13185
Gallon, M., Clairfeuille, T., Collins, B. M. and Cullen, P. J. (2014). A unique PDZ domain and arrestin-like fold interaction reveals mechanistic details of endocytic recycling by SNX27-retromer. ASCB/IFCB Meeting, Philadelphia Pa, Dec 06-10, 2014. BETHESDA: AMER SOC CELL BIOLOGY.
Ghai, R., Mobli, M., Norwood, S. J., Bugarcic, A., Teasdale, R. D., King, G. F. and Collins, B. M. (2012). PX family proteins at the interface between intracellular trafficking and signalling. 22nd IUBMB Congress/37th FEBS Congress, Seville, Spain, 4-9 September 2012. Chichester, West Sussex, United Kingdom: Wiley-Blackwell. doi: 10.1111/j.1742-4658.2010.08705.x
Collins, BM and Owen, DJ (2004). Structural studies of clathrin adaptors. Annual Meeting of the American-Society-for-Cell-Biology, Washington Dc, Dec 04-08, 2004. BETHESDA: AMER SOC CELL BIOLOGY.
Data Collection
Collins, Brett (2018). X-ray diffraction images related to PDB file 6E8R. The University of Queensland. (Dataset) doi: 10.14264/uql.2018.497