Dr Gabriela-Oana Bodea
Research Fellow
Queensland Brain Institute
+61 7 344 37688
Researcher biography
Dr. Gabriela Bodea received her PhD in 2014 with highest honours (Summa cum laude) from the University of Bonn, Germany. Subsequently, Dr Bodea joined the Genome Plasticity and Disease group at the Mater Research Institute in Australia. Here, Dr. Bodea began investigating the role of LINE-1 retrotransposons, a class of mobile DNA elements colloquially referred to as "jumping genes", in creating genetic variability within neurons. In 2017, Dr. Bodea joined the Queensland Brain Institute, University of Queensland, where she is currently a Research Fellow in the Computational and Molecular Biology lab. Dr. Bodea's research aims to understand how the dynamic regulation of retrotransposons shapes neuronal identity in the mammalian brain and why certain neuronal subtypes are more susceptible to neurodegenerative and neuropsychiatric disorders. Dr Bodea's work has been supported by prestigious fellowships awarded by the German Research Foundation (DFG) and the NHMRC-ARC Dementia Research Development. Dr. Bodea has published in top journals such as Nature Neuroscience, Cell Reports, Genome Research, and Development. Dr Bodea has also been involved in the training and mentorship of MSc and PhD students and participated in course coordination and lecturing activities.
Book Chapter
Kempen, Marie-Jeanne H. C., Bodea, Gabriela O. and Faulkner, Geoffrey J. (2017). Neuronal genome plasticity: retrotransposons, environment and disease. Human retrotransposons in health and disease. (pp. 107-125) edited by Gael Cristofari. Cham, Switzerland: Springer. doi: 10.1007/978-3-319-48344-3_5
Journal Articles
Bodea, Gabriela O., Botto, Juan M., Ferreiro, Maria E., Sanchez-Luque, Francisco J., de los Rios Barreda, Jose, Rasmussen, Jay, Rahman, Muhammed A., Fenlon, Laura R., Jansz, Natasha, Gubert, Carolina, Gerdes, Patricia, Bodea, Liviu-Gabriel, Ajjikuttira, Prabha, Da Costa Guevara, Darwin J., Cumner, Linda, Bell, Charles C., Kozulin, Peter, Billon, Victor, Morell, Santiago, Kempen, Marie-Jeanne H. C., Love, Chloe J., Saha, Karabi, Palmer, Lucy M., Ewing, Adam D., Jhaveri, Dhanisha J., Richardson, Sandra R., Hannan, Anthony J. and Faulkner, Geoffrey J. (2024). LINE-1 retrotransposons contribute to mouse PV interneuron development. Nature Neuroscience, 27 (7), 1-34. doi: 10.1038/s41593-024-01650-2
Madrid, Lidia I., Hafey, Katelyn, Bandhavkar, Saurabh, Bodea, Gabriela O., Jimenez-Martin, Javier, Milne, Michael, Walker, Tara L., Faulkner, Geoffrey J., Coulson, Elizabeth J. and Jhaveri, Dhanisha J. (2024). Stimulation of the muscarinic receptor M4 regulates neural precursor cell proliferation and promotes adult hippocampal neurogenesis. Development, 151 (1) dev201835, 1-13. doi: 10.1242/dev.201835
Gerdes, Patricia, Chan, Dorothy, Lundberg, Mischa, Sanchez-Luque, Francisco J., Bodea, Gabriela O., Ewing, Adam D., Faulkner, Geoffrey J. and Richardson, Sandra R. (2023). Locus-resolution analysis of L1 regulation and retrotransposition potential in mouse embryonic development. Genome Research, 33 (9), 1465-1481. doi: 10.1101/gr.278003.123
Bodea, Gabriela O. and Yemisci, Muge (2023). Methods and applications in cellular neuropathology.. Frontiers in Cellular Neuroscience, 17 1244414, 1244414. doi: 10.3389/fncel.2023.1244414
Billon, Victor, Sanchez-Luque, Francisco J, Rasmussen, Jay, Bodea, Gabriela O, Gerhardt, Daniel J, Gerdes, Patricia, Cheetham, Seth W, Schauer, Stephanie N, Ajjikuttira, Prabha, Meyer, Thomas J, Layman, Cora E, Nevonen, Kimberly A, Jansz, Natasha, Garcia-Perez, Jose L, Richardson, Sandra R, Ewing, Adam D, Carbone, Lucia and Faulkner, Geoffrey J (2022). Somatic retrotransposition in the developing rhesus macaque brain. Genome Research, 32 (7), gr.276451.121-1314. doi: 10.1101/gr.276451.121
Tolve, Marianna , Ulusoy, Ayse, Patikas, Nikolaos, Islam, K. Ushna S. , Bodea, Gabriela O. , Öztürk, Ece, Broske, Bianca, Mentani, Astrid , Wagener, Antonia , van Loo, Karen M.J. , Britsch, Stefan , Liu, Pengtao , Khaled, Walid T. , Metzakopian, Emmanouil , Baader, Stephan L. , Di Monte, Donato A. and Blaess, Sandra (2021). The transcription factor BCL11A defines distinct subsets of midbrain dopaminergic neurons. Cell Reports, 36 (11) 109697, 109697. doi: 10.1016/j.celrep.2021.109697
Rasmussen, Jay, Ewing, Adam D., Bodea, Liviu‐Gabriel, Bodea, Gabriela O., Gearing, Marla and Faulkner, Geoffrey J. (2021). An early proinflammatory transcriptional response to tau pathology is age‐specific and foreshadows reduced tau burden. Brain Pathology, 32 (3) e13018, e13018. doi: 10.1111/bpa.13018
Smits, Nathan, Rasmussen, Jay, Bodea, Gabriela O., Amarilla, Alberto A., Gerdes, Patricia, Sanchez-Luque, Francisco J., Ajjikuttira, Prabha, Modhiran, Naphak, Liang, Benjamin, Faivre, Jamila, Deveson, Ira W., Khromykh, Alexander A., Watterson, Daniel, Ewing, Adam D. and Faulkner, Geoffrey J. (2021). No evidence of human genome integration of SARS-CoV-2 found by long-read DNA sequencing. Cell Reports, 36 (7) 109530, 109530. doi: 10.1016/j.celrep.2021.109530
Bodea, Gabriela O., McKelvey, Eleanor G. Z. and Faulkner, Geoffrey J. (2018). Retrotransposon-induced mosaicism in the neural genome. Open Biology, 8 (7) 180074, 180074. doi: 10.1098/rsob.180074
Richardson, Sandra R., Gerdes, Patricia, Gerhardt, Daniel J., Sanchez-Luque, Francisco J., Bodea, Gabriela-Oana, Muñoz-Lopez, Martin, Jesuadian, J. Samuel, Kempen, Marie-Jeanne H. C., Carreira, Patricia E., Jeddeloh, Jeffrey A., Garcia-Perez, Jose L., Kazazian Jr., Haig H., Ewing, Adam D. and Faulkner, Geoffrey J. (2017). Heritable L1 retrotransposition in the mouse primordial germline and early embryo. Genome Research, 27 (8), 1395-1405. doi: 10.1101/gr.219022.116
Bodea, Gabriela O. and Blaess, Sandra (2015). Establishing diversity in the dopaminergic system. FEBS Letters (Federation of European Biochemical Socities), 589 (24, Part A), 3773-3785. doi: 10.1016/j.febslet.2015.09.016
Upton, Kyle R., Gerhardt, Daniel J., Jesuadian, J. Samuel, Richardson, Sandra R., Sanchez-Luque, Francisco J., Bodea, Gabriela O., Ewing, Adam D., Salvador-Palomeque, Carmen, van der Knaap, Mario S., Brennan, Paul M., Vanderver, Adeline and Faulkner, Geoffrey J. (2015). Ubiquitous L1 mosaicism in hippocampal neurons. Cell, 161 (2), 228-239. doi: 10.1016/j.cell.2015.03.026
Bodea, Gabriela Oana, Spille, Jan-Hendrik, Abe, Philipp, Andersson, Aycan Senturk, Acker-Palmer, Amparo, Stumm, Ralf, Kubitscheck, Ulrich and Blaess, Sandra (2014). Reelin and CXCL12 regulate distinct migratory behaviors during the development of the dopaminergic system. Development, 141 (3), 661-673. doi: 10.1242/dev.099937
Barry, David, Roque, Hélio, Dumoux, Maud, Kriston-Vizi, Janos, Bodea, Gabriela O. and Harper, Callista (2013). Meeting report. Imaging in cell biology: where next?. Journal of Cell Science, 126 (1), 43-44. doi: 10.1242/jcs.129197
Bodea, Gabriela Oana and Blaess, Sandra (2012). Organotypic slice cultures of embryonic ventral midbrain: a system to study dopaminergic neuronal development in vitro. Journal of Visualized Experiments : JoVE (59) e3350, e3350-7. doi: 10.3791/3350
Blaess, Sandra, Bodea, Gabriela O., Kabanova, Anna, Chanet, Soline, Mugniery, Emilie, Derouiche, Amin, Stephen, Daniel and Joyner, Alexandra L. (2011). Temporal-spatial changes in Sonic Hedgehog expression and signaling reveal different potentials of ventral mesencephalic progenitors to populate distinct ventral midbrain nuclei. Neural Development, 6 (29) 1749. doi: 10.1186/1749-8104-6-29
Dinu, Diana, Bodea, Gabriela Oana, Ceapa, Corina Diana, Munteanu, Maria Cristina, Roming, Florentina Israel, Serban, Andreea Iren, Hermenean, Anca, Costache, Marieta, Zarnescu, Otilia and Dinischiotu, Anca (2011). Adapted response of the antioxidant defense system to oxidative stress induced by deoxynivalenol in Hek-293 cells. Toxicon, 57 (7-8), 1023-1032. doi: 10.1016/j.toxicon.2011.04.006
Bodea, G. O. Dragomir, Munteanu, M. C., Dinu, D., Serban, A. I., Roming, F. Israel, Costache, M. and Dinischiotu, A. (2009). Influence of deoxynivalenol on the oxidative status of HepG2 cells. Romanian Biotechnological Letters, 14 (2), 4349-4359.
Dragomir, G., Huculeci, R., Munteanu, C., Ceapa, C., Bodea, L. and Dinischiotu, A. (2007). The effect of deoxynivalenol on hepatic cell line HepG2. Biotechnology in Animal Husbandry, 23 (5-6-1), 583-588. doi: 10.2298/bah0701583d
Preprint
Bodea, Gabriela O., Ferreiro, Maria E., Sanchez-Luque, Francisco J., Botto, Juan M., Rasmussen, Jay, Rahman, Muhammed A., Fenlon, Laura R., Gubert, Carolina, Gerdes, Patricia, Bodea, Liviu-Gabriel, Ajjikuttira, Prabha, Kozulin, Peter, Billon, Victor, Morell, Santiago, Kempen, Marie-Jeanne H.C., Love, Chloe J., Palmer, Lucy M., Ewing, Adam D., Jhaveri, Dhanisha J., Richardson, Sandra R., Hannan, Anthony J. and Faulkner, Geoffrey J. (2022). LINE-1 retrotransposon activation intrinsic to interneuron development.