Speaker : 

A/Professor Zachary Knight
Howard Hughes Medical Institute, University of California, San Francisco

Title: "The Neurobiology of Homeostasis"

Abstract: Our research investigates the neural mechanisms that govern hunger and thirst. Nearly a century ago, lesioning studies suggested that these fundamental drives originate from subcortical stuctures such as hypothalamus that are specialized for monitoring internal state. However the structure and dynamics of the underlying neural circuits has been poorly defined. I will discuss our work using calcium imaging to record the natural activity of some of the key cell types that control eating and drinking in vivo. We have discovered that these homeostatic neurons receive sensory information from the outside world, which they use predict impending physiologic changes and adjust behavior preemptively. I will discuss our work investigating how these homeostatic circuits integrate external sensory cues with internal signals arising from the  body in order to generate and shape goal-directed behaviors.

 

 

About Neuroscience Seminars

Neuroscience seminars at the QBI play a major role in the advancement of neuroscience in the Asia-Pacific region. The primary goal of these seminars is to promote excellence in neuroscience through the exchange of ideas, establishing new collaborations and augmenting partnerships already in place.

The scheduled QBI Neuroscience Seminar series are held on Wednesdays from 11am-12pm in the Level 7 Auditorium of the Queensland Brain Institute, Building 79, St Lucia Campus, The University of Queensland. Additional seminars may be held at other times as listed below.

 

Neuroscience Seminars archive 2005-2018