Professor Geoff Goodhill, UQ : "The development of neural coding in zebrafish, and a new method for analysing calcium imaging data"
Speaker :
Professor Geoff Goodhill
Queensland Brain Institute, University of Queensland
Title: "The development of neural coding in zebrafish, and a new method for analysing calcium imaging data"
I will first describe our recent work using high-speed imaging of behaviour and 2-photon imaging of brain activity to investigate how neural coding develops in the larval zebrafish. We show that hunting performance improves over development, the neural code refines non-uniformly over the optic tectum, and evoked and spontaneous activity diverge over development. I will then present a new statistical model of calcium imaging data that reveals the extent to which neurons are driven by visual stimuli, latent sources of spontaneous activity, and their interaction. This broadly applicable model brings new insight into population-level neural activity in single trials without averaging away potentially important information encoded in spontaneous activity (https://www.biorxiv.org/content/10.1101/691261v1).
About Neuroscience Seminars
Neuroscience seminars at the QBI play a major role in the advancement of neuroscience in the Asia-Pacific region. The primary goal of these seminars is to promote excellence in neuroscience through the exchange of ideas, establishing new collaborations and augmenting partnerships already in place.
Seminars in the QBI Auditorium are held on Wednesdays at 12-1pm, which are sometimes simulcast on Zoom (with approval from the speaker). We also occassionally hold seminars from international speakers via Zoom. The days and times of these seminars will vary depending on the time zone of the speaker. Please see each seminar listed below for details.
