A/Professor Jeremy Dittmann, USA : “Molecular Control of Synaptic Vesicle Fusion”
Speaker :
A/Professor Jeremy Dittmann
Cornell Medical School, New York, USA
Title: “Molecular Control of Synaptic Vesicle Fusion”
Abstract: Our research group uses a combination of physiology, genetics, imaging, and biochemistry to dissect the molecular mechanisms underlying synaptic transmission. In particular, we study presynaptic function in C. elegans as a model nervous system with a focus on the core secretory machinery at the synapse such as SNAREs, Munc18, Munc13, and Complexin. Studies from our lab and in collaboration with David Eliezer’s group at Weill Cornell have unveiled a novel curvature-sensing domain in Complexin that is required for proper localization and inhibitory function. Recent work on the essential synaptic protein Munc13 has revealed critical mechanistic features in the processes of vesicle priming and fusion.
About Neuroscience Seminars
Neuroscience seminars at the QBI play a major role in the advancement of neuroscience in the Asia-Pacific region. The primary goal of these seminars is to promote excellence in neuroscience through the exchange of ideas, establishing new collaborations and augmenting partnerships already in place.
Seminars in the QBI Auditorium are held on Wednesdays at 12-1pm, which are sometimes simulcast on Zoom (with approval from the speaker). We also occassionally hold seminars from international speakers via Zoom. The days and times of these seminars will vary depending on the time zone of the speaker. Please see each seminar listed below for details.
