Speaker :

A/Professor Jeremy Dittmann

Cornell Medical School, New York, USA

Title: “Molecular Control of Synaptic Vesicle Fusion”

Abstract: Our research group uses a combination of physiology, genetics, imaging, and biochemistry to dissect the molecular mechanisms underlying synaptic transmission.  In particular, we study presynaptic function in C. elegans as a model nervous system with a focus on the core secretory machinery at the synapse such as SNAREs, Munc18, Munc13, and Complexin.  Studies from our lab and in collaboration with David Eliezer’s group  at Weill Cornell have unveiled a novel curvature-sensing domain in Complexin that is required for proper localization and inhibitory function.  Recent work on the essential synaptic protein Munc13 has revealed critical mechanistic features in the processes of vesicle priming and fusion.
 

About Neuroscience Seminars

Neuroscience seminars at the QBI play a major role in the advancement of neuroscience in the Asia-Pacific region. The primary goal of these seminars is to promote excellence in neuroscience through the exchange of ideas, establishing new collaborations and augmenting partnerships already in place.

The scheduled QBI Neuroscience Seminar series are held on Wednesdays from 11am-12pm in the Level 7 Auditorium of the Queensland Brain Institute, Building 79, St Lucia Campus, The University of Queensland. Additional seminars may be held at other times as listed below.

 

Neuroscience Seminars archive 2005-2018