Marge Maallo (PhD Exit Seminar)

Queensland Brain Institute, University of Queensland

Title: Neural correlates of visual function in agenesis of the corpus callosum

Abstract: An assault on the development of the corpus callosum in utero does not seem to have the same prominent effects on behaviour as those of surgical callosal section in adults. This makes dysgenesis of the corpus callosum (DCC) a good model for studying brain plasticity to understand how the brain compensates for abnormal development. Individuals with DCC have been shown to behave normally for tasks that require high-order processing and communication between the two cerebral hemispheres. In this study, I looked at low-level visual integration across two hemifields in adults with DCC and found deficits in interhemispheric processing in most participants that is expected in relation to the callosal pathology. However, they also exhibited intrahemispheric deficits when performing tasks concerning low-level visual features. I then looked at how the retinotopic maps in these individuals are organised. Functional aspects of retinotopic organisation present as typical, but its relation to anatomical landmarks are atypical that could be related to the behavioural deficits. I found no direct connection between the left and right functional primary visual cortex. Overall, the results indicate that there is a disconnection in DCC concerning low-level visual features. Going forward, these results can help us design better interventions for alleviating outcomes and lifestyle for individuals with DCC.

About Neuroscience Seminars

Neuroscience seminars at the QBI play a major role in the advancement of neuroscience in the Asia-Pacific region. The primary goal of these seminars is to promote excellence in neuroscience through the exchange of ideas, establishing new collaborations and augmenting partnerships already in place.

The scheduled QBI Neuroscience Seminar series are held on Wednesdays from 11am-12pm in the Level 7 Auditorium of the Queensland Brain Institute, Building 79, St Lucia Campus, The University of Queensland. Additional seminars may be held at other times as listed below.


Neuroscience Seminars archive 2005-2018