Mindful Moves, Healthy Hearts: Translational Research for Dementia and Cardiovascular Protection through Physical Activity and Cardiorespiratory Fitness
Speakers: Professor Ulrik Wisløff and Dr Atefe Rafiee Tari
Department of Circulation and Medical Imaging
Norwegian University of Science and Technology
The Cardiac Exercise Research Group (CERG, ntnu.edu/cerg) aims to define optimal exercise programs for everyday people to increase the likelihood of development and preservation of good health throughout life. Professor Ulrik Wisloff and Dr Atefe R. Tari will take us through how their research groups truly translational research findings, ranging from cells, experimental models of exercise, clinical trials, and population-based studies (and back again), has quickly translated into clinical practice.
Title: World’s largest exercise trials in healthy ageing and myocardial infarction
Abstract: Ulrik will present how epidemiological and experimental research projects (population studies, cell-studies, animal models) ended up in the world’s largest exercise trial. With the NorEx study - The Norwegian Trial of Physical Exercise After Myocardial Infarction - they aim to find out for the first time whether exercise prolongs life and prevents new serious disease (including dementias) in 9700 patients who have been treated for myocardial infarction. He will also present the Generation 100 Study that, in 2012, included more than 1500 women and men in their 70s. The aim was to find out if exercise over 5 years gave older adults a longer and healthier life. The study is the largest of its kind, and the ten-year testing of the participants was completed in 2023. Both projects produce data for interested researchers (including brain scientists) for the next generations.
Title: Do Physical Activity and Cardiorespiratory Fitness Hold the Key to Prevent Dementia?
Abstract: In this talk Atefe will give an overview of their epidemiological studies exploring the connection between physical activity and cardiorespiratory fitness to risk of developing dementia. She will thereafter present their experimental (cell and animals) data on treatment effect of exercise-induced molecular mechanisms on the Alzheimer's brain. Finally, she will present the ExPlas trial (Exercised Plasma to Treat Alzheimer´s Disease), where they test whether plasma from fit young donors can be used to treat patients in early-stage Alzheimer´s disease.
About Neuroscience Seminars
Neuroscience seminars at the QBI play a major role in the advancement of neuroscience in the Asia-Pacific region. The primary goal of these seminars is to promote excellence in neuroscience through the exchange of ideas, establishing new collaborations and augmenting partnerships already in place.
Seminars in the QBI Auditorium are held on Wednesdays at 12-1pm, which are sometimes simulcast on Zoom (with approval from the speaker). We also occassionally hold seminars from international speakers via Zoom. The days and times of these seminars will vary depending on the time zone of the speaker. Please see each seminar listed below for details.
