Speaker:

Professor Massimo Hilliard
Queensland Brain Institute, University of Queensland

Title:  "Fusogen-mediated neuron-neuron fusion: impact on neuronal function, connectivity, and behaviour" 

Abstract:

The 100-year old neuron doctrine from Ramón y Cajal states that neurons are individual cells, rejecting the process of cell-cell fusion in the normal development and function of the nervous system.  However, fusogens - specialized molecules essential and sufficient for the fusion of cells - are expressed in the nervous system of different species under conditions of viral infection, stress, or disease.  Despite these findings, whether expression of fusogens in neurons leads to cell-cell fusion, and if so, whether this affects neuronal fate, function, and animal behavior, has not been explored.  Our recent results provide new insights into how fusogens and viral infections affect the nervous system, altering its function and connectivity and causing neuropathology. 

 

 

 

About Neuroscience Seminars

Neuroscience seminars at the QBI play a major role in the advancement of neuroscience in the Asia-Pacific region. The primary goal of these seminars is to promote excellence in neuroscience through the exchange of ideas, establishing new collaborations and augmenting partnerships already in place.

While seminars in the QBI Auditorium have been suspended due to COVID-19, we will still be holding seminars via Zoom. The days and times of these seminars will vary depending on the time zone of the speaker. Please see each seminar listed below for details. 

 

Neuroscience Seminars archive 2005-2018