Professor Sebastian Jessberger, Switzerland : "Molecular and functional properties of hippocampal stem cells"
Speaker:
Professor Sebastian Jessberger,
Laboratory of Neural Plasticity, Brain Research Institute
University of Zurich, Switzerland
Title: "Molecular and functional properties of hippocampal stem cells"
Abstract:
Neural stem cells generate new neurons throughout life in distinct regions of the mammalian brain. This process, called adult neurogenesis, is critically involved in certain forms of learning and memory. In addition, failing or altered neurogenesis has been associated with a number of neuro-psychiatric diseases such as major depression and cognitive aging. We aim to characterize the cellular and molecular mechanisms regulating neural stem cell activity and behavior on a single cell level. We present new approaches to study the cellular principles underlying life-long neurogenesis using imaging-based tools and single cell molecular profiling. Further, we provide evidence for novel molecular mechanisms governing the neurogenic process in the mammalian brain. Thus, the data presented provide new insights into the cellular principles of hippocampal neurogenesis and identify novel mechanisms regulating the behavior of hippocampal stem cells across lifespan.
About Neuroscience Seminars
Neuroscience seminars at the QBI play a major role in the advancement of neuroscience in the Asia-Pacific region. The primary goal of these seminars is to promote excellence in neuroscience through the exchange of ideas, establishing new collaborations and augmenting partnerships already in place.
Seminars in the QBI Auditorium on Level 7 are held on Wednesdays at 12-1pm, which are sometimes simulcast on Zoom (with approval from the speaker). We also occassionally hold seminars from international speakers via Zoom. The days and times of these seminars will vary depending on the time zone of the speaker. Please see each seminar listed below for details.
