Associate Professor Andy Shih
Seattle Children’s Research Institute,  Center for Developmental Biology and Regenerative Medicine, University of Washington, Seattle, USA

Title: "Optical dissection of brain capillary function"


My laboratory uses in vivo multiphoton imaging and rodent models to shed light (quite literally) on regulation of cerebral blood flow. In particular, we have focused recent attention on the vast capillary networks that distribute blood throughout the brain. We use light to both visualize capillary structure and flow, as well as noninvasively manipulate neurovascular cells that control capillary flow. In my talk, I will walk the audience through our motivation for studying brain capillaries across the lifespan. I will talk about our recent findings on construction of capillary networks during early postnatal development, regulation of blood flow by pericytes, and capillary changes in gray and white matter that may contribute to metabolic insufficiencies arising with age and dementia. 


About Neuroscience Seminars

Neuroscience seminars at the QBI play a major role in the advancement of neuroscience in the Asia-Pacific region. The primary goal of these seminars is to promote excellence in neuroscience through the exchange of ideas, establishing new collaborations and augmenting partnerships already in place.

Seminars in the QBI Auditorium on Level 7 are held on Wednesdays at 12-1pm, which are sometimes simulcast on Zoom (with approval from the speaker). We also occassionally hold seminars from international speakers via Zoom. The days and times of these seminars will vary depending on the time zone of the speaker. Please see each seminar listed below for details. 


Neuroscience Seminars archive 2005-2018