Speaker:

Professor Subhojit Roy
Departments of Pathology and Neurosciences, University of California, San Diego
La Jolla CA92093-0626, USA

Title: "Unusual trafficking Routes in Axonal Transport"

Abstract:  Due to their complex geometry and finite sites of bulk protein synthesis in the perikarya, neurons have evolved elaborate transport and trafficking machinery to deliver proteins into axons and dendrites. Knowledge into the biology of this process is critical to our understanding of neuronal form and function. Disrupted trafficking is also a feature of many neurodegenerative diseases, and trafficking-routes can often be harnessed for therapeutic manipulations - underscoring their relevance to health and disease. This talk will focus on the unusual modes of trafficking employed by cytosolic ("soluble") and cytoskeletal proteins that comprise the majority of transported material, yet are the least studied among all transport cargoes; sluggishly moving in a mysterious rate-class called slow axonal transport.   
 

About Neuroscience Seminars

Neuroscience seminars at the QBI play a major role in the advancement of neuroscience in the Asia-Pacific region. The primary goal of these seminars is to promote excellence in neuroscience through the exchange of ideas, establishing new collaborations and augmenting partnerships already in place.

The scheduled QBI Neuroscience Seminar series are held on Wednesdays from 11am-12pm in the Level 7 Auditorium of the Queensland Brain Institute, Building 79, St Lucia Campus, The University of Queensland. Additional seminars may be held at other times as listed below.

 

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