Poster abstracts 

Adekunle T Bademosi, Adam K Walker. Pathogenic motor neuron disease-linked mutations distinctly alter TDP-43 nanoscale dynamics.

Alison K Carlisle, Jürgen Götz, Liviu-Gabriel Bodea. Fibril amyloid-β decreases de novo protein synthesis in microglia in vitro.

Barbora Fulopova, William Bennett, Kimberley Stuart, Aidan Bindoff,  Anna King, James Vickers, Alison Canty. Cortical axonal synapses maintain density, but not turnover in the APP/PS1 amyloidosis mouse model.

Elise Kellett. Exploring TDP-43 phosphorylation through kinases.

Xiaoqing Alice Zhou, Lei Qian, Zengmin Li, Grace Ngiam, Elizabeth J. Coulson, Kai-Hsiang Chuang.

Kornraviya Sankorrakul, Theodora A Constantin, Jacinta J Conroy, Lei Qian, Leda Kasas, Sonja Meier, Thomas Cleland, Frank Longo, Elizabeth J Coulson.

Emily McCann, Soohyun Lee, Felicia Coleman, John O'Sullivan, Peter Nestor. Pareidolias as misperceptions in Lewy Body Disorders.

Gerhard Leinenga, Daniel Blackmore, Rucha Pandit, Liviu Bodea, Wee Kiat Koh, Jae Song, and Jürgen Götz. Mechanisms of therapeutic ultrasound as a therapeutic modality for Alzheimer’s disease.

Gina Richter-Stretton, Gerhard Leinenga, Wendy Lee, Matthew Pelekanos, Jae Song, Antony Chicoteau, Soo Lee, Felicia Coleman, Caitlin McElligott, Anthony Harris, Henry Beale, Jason Mattingley, Peter Nestor, Rachel De Las Heras, Jürgen Götz. Scanning ultrasound translation.

Heledd Brown-Wright, Lidia Madrid San Martin, Leon Luan, Leszek Lisowski, Marco Morsch, Adam Walker.

Xuan Ling Hilary Yong, Lingrui Zhang, Liming Yang, Xiumin Chen, Jing Zhi Anson Tan, Xiaojun Yu, Mintu Chandra, Emma Livingstone, Jocelyn Widagdo, Marta M Vieira, Katherine W Roche, Joseph W Lynch, Angelo Keramidas, Brett M Collins, Victor Anggono. Regulation of NMDA receptor trafficking and gating by activity-dependent CaMKIIα phosphorylation of the GluN2A subunit.

Jonathan Lee , Adam Briner, Rumelo Amor, Jürgen Götz, Pranesh Padmanabhan,.Super-resolution imaging reveals ZO1 nanoscale and microscale domains linked to focal adhesions at the basal membrane.

Juan Carlos Polanco, Yevhen Akimov, Avinash Fernandes, Adam Briner, Gabriel Hand, Giuseppe Balistreri, and Jürgen Götz. Genome-wide CRISPRi screening reveals regulators of Alzheimer’s tau pathology shared between exosomal and vesicle-free tau seeds.

Juliana Venturato, Rebecca San Gil, Adekunle Bademosi, Adam Walker. Development of new viral-mediated cell models of ALS-linked UBQLN2 pathology.

Julio Aguado, Alberto A. Amarilla, Atefeh Taherian Fard, Eduardo A. Albornoz, Alexander Tyshkovskiy, Marius Schwabenland, Harman K. Chaggar, Naphak Modhiran, Cecilia Gómez-Inclán, Ibrahim Javed, Alireza A. Baradar, Benjamin Liang, Malindrie Dharmaratne, Giovanni Pietrogrande, Pranesh Padmanabhan, Morgan E. Freney, Rhys Parry, Julian D.J. Sng, Ariel Isaacs, Alexander A. Khromykh, Alejandro Rojas-Fernandez, Thomas P. Davis, Marco Prinz, Bertram Bengsch, Vadim N. Gladyshev, Trent M. Woodruff, Jessica C. Mar, Daniel Watterson, and Ernst J. Wolvetang. Senolytic therapy alleviates physiological human brain aging and COVID-19 neuropathology.

Zengmin Li, Dilsher Athwal, Hsu-Lei Lee, Pankaj Sah, Patricio Opazo, Kai-Hsiang Chuang. Locating causal hubs of memory consolidation in spontaneous brain network.

Lidia I. Madrid, Heledd Brown-Wright, Leon Luan, Adam Walker. Behavioural validation of the rNLS8 TDP-43 mouse model on a pure C57BL/6J background.

Lingrui Zhang, Qian Guo, Mark E. Graham, Brett M. Collins and Victor Anggono. Sorting nexin 27 (SNX27) is a substrate of the Ca2+/calmodulin-dependent protein kinase IIα (CaMKIIα).

Liviu-Gabriel Bodea, Alison K. Carlisle, Riku Sato, Jürgen Götz. Postnatal brain development dysregulations in a novel microglial Tyrobp mouse model. 

Matisse Jacobs, Rebecca San Gil, Adam Walker. Investigating novel modulators of TDP-43 pathology using human iPSCderived
neuronal models.

Montana Samantzis. Effects of non-invasive brain stimulation on neural and behavioural.

Lei Li. The C2 and PH domain of CAPS constitute an effective PI(4,5)P2-binding unit essential for Ca2+-regulated exocytosis.

Odette Leiter, Suse Seidemann, Rupert W. Overall, Beáta Ramasz, Nicole Rund, Sonja Schallenberg, Tatyana Grinenko, Ben Wielockx, Gerd Kempermann, and Tara L. Walker. Exercise-induced activated platelets increase adult hippocampal neurogenesis.

Rebecca San Gil, Jon Xu, Karla J Cowley, Max Ma, Sohye Yoon, Kaylene J Simpson, Adam Walker. Genome-wide CRISPR screens to identify modulators of TDP-43 aggregation in ALS.

Refik Kanjhan. Copper Neurotoxicity in old-aged Retinal Ganglion Cells Involves Inhibition of Na.

Sean S. Keating, Adekunle T. Bademosi, Rebecca San Gil, Adam K. Walker. CRISPR-tagging for live-cell analyses of endogenous TDP-43 protein aggregation dynamics in ALS and FTD models.

Sven Storch. Entrainment of gamma oscillations by sensory stimulation in the acute phase after stroke improves functional recovery. 

Wei Luan, Amanda Wright, Heledd Brown-Wright, Rebecca San Gil, Lidia Madrid San Martin, Adam Walker. Early activation of cell stress and death pathways due to TDP-43.

Liyu Chen, Ratneswary Sutharsan, Jonathan LF Lee, Esteban Cruz, Blaise Asnicar, Tishila Palliyaguru, Joanna M Wasielewska; Arnaud Gaudin, Jae Song, Gerhard Leinenga & Jürgen Götz. Improving the safety profile of focused ultrasound in blood-brain barrier opening by using a
combinatorial strategy that involves a claudin-5-specific binder.

Haowen Liu. CASK and FARP localize two classes of post-synaptic ACh receptors thereby promoting cholinergic transmission.

Rapid Talk Abstracts - ECR

Barbora Fulopova, William Bennett, Kimberley Stuart, Aidan Bindoff, Anna King, James Vickers, Alison Canty. Cortical axonal synapses maintain density, but not turnover in the APP/PS1 amyloidosis mouse model.

Julio Aguado, Alberto A. Amarilla, Atefeh Taherian Fard, Eduardo A. Albornoz, Alexander Tyshkovskiy, Marius Schwabenland, Harman K. Chaggar, Naphak Modhiran, Cecilia Gómez-Inclán, Ibrahim Javed, Alireza A. Baradar, Benjamin Liang, Malindrie Dharmaratne, Giovanni Pietrogrande, Pranesh Padmanabhan, Morgan E. Freney, Rhys Parry, Julian D.J. Sng, Ariel Isaacs, Alexander A. Khromykh, Alejandro Rojas-Fernandez, Thomas P. Davis, Marco Prinz, Bertram Bengsch, Vadim N. Gladyshev, Trent M. Woodruff, Jessica C. Mar, Daniel Watterson, and Ernst J. Wolvetang. Senolytic therapy alleviates physiological human brain aging and COVID-19 neuropathology.

Adekunle T Bademosi, Adam K Walker. Pathogenic motor neuron disease-linked mutations distinctly alter TDP-43 nanoscale dynamics.

Liyu Chen, Ratneswary Sutharsan, Jonathan LF Lee, Esteban Cruz, Blaise Asnicar, Tishila Palliyaguru, Joanna M Wasielewska; Arnaud Gaudin, Jae Song, Gerhard Leinenga & Jürgen Götz. Improving the safety profile of focused ultrasound in blood-brain barrier opening by using a combinatorial strategy that involves a claudin-5-specific binder.

Zengmin Li, Dilsher Athwal, Hsu-Lei Lee, Pankaj Sah, Patricio Opazo, Kai-Hsiang Chuang. Locating causal hubs of memory consolidation in spontaneous brain network.

Rapid Talk Abstracts - Students 

Ana Batallas-Borja, Mintu Chandra, Jing Zhi Anson Tan, Huimin Guo, Se Eun Jang, Brett M. Collins and Victor Anggono. Copine-6 binding to phospholipids is essential for AMPA receptor exocytosis during synaptic potentiation.

Xuan Ling, Hilary Yong, Lingrui Zhang, Liming Yang, Xiumin Chen, Jing Zhi Anson Tan, Xiaojun Yu, Mintu Chandra, Emma Livingstone, Jocelyn Widagdo, Marta M Vieira, Katherine W Roche, Joseph W Lynch, Angelo Keramidas, Brett M Collins, Victor Anggono. Regulation of NMDA receptor trafficking and gating by activity-dependent CaMKIIα phosphorylation of the GluN2A subunit.

Matisse Jacobs, Rebecca San Gil, Adam Walker. Investigating novel modulators of TDP-43 pathology using human iPSCderived
neuronal models.

Montana Samantzis. Effects of non-invasive brain stimulation on neural and behavioural changes following stroke.

Sven Storch. Entrainment of gamma oscillations by sensory stimulation in the acute phase after stroke improves functional recovery.