Cooper publications
BDNF-dependent nano-organization of Neogenin and the WAVE regulatory complex promotes actin remodeling in dendritic spines
Shohayeb, Belal, Sempert, Kai, Wallis, Tristan P., Meunier, Frédéric A., Durisic, Nela, O'Brien, Elizabeth A., Flores, Cecilia, and Cooper, Helen M. (2024). BDNF-dependent nano-organization of Neogenin and the WAVE regulatory complex promotes actin remodeling in dendritic spines. iScience 27 (9) 110621 110621. https://doi.org/10.1016/j.isci.2024.110621
RGMa and Neogenin control dendritic spine morphogenesis via WAVE Regulatory Complex-mediated actin remodeling
Sempert, Kai, Shohayeb, Belal, Lanoue, Vanessa, O’Brien, Elizabeth A., Flores, Cecilia, and Cooper, Helen M. (2023). RGMa and Neogenin control dendritic spine morphogenesis via WAVE Regulatory Complex-mediated actin remodeling. Frontiers in Molecular Neuroscience 16 1253801 . https://doi.org/10.3389/fnmol.2023.1253801
Embryonic stem cell-derived neurons as a model system for epigenome maturation during development
Martin, Sally, Poppe, Daniel, Olova, Nelly, O’Leary, Conor, Ivanova, Elena, Pflueger, Jahnvi, Dechka, Jennifer, Simmons, Rebecca K., Cooper, Helen M., Reik, Wolf, Lister, Ryan, and Wolvetang, Ernst J. (2023). Embryonic stem cell-derived neurons as a model system for epigenome maturation during development. Genes 14 (5) 957 957. https://doi.org/10.3390/genes14050957
The ups and downs of Pax6 in neural stem cells
Shohayeb, Belal and Cooper, Helen M. (2023). The ups and downs of Pax6 in neural stem cells. Journal of Biological Chemistry 299 (5) 104680 104680. https://doi.org/10.1016/j.jbc.2023.104680
Hydrocephalus in Nfix−/− mice is underpinned by changes in ependymal cell physiology
Harkins, Danyon, Harvey, Tracey J., Atterton, Cooper, Miller, Ingrid, Currey, Laura, Oishi, Sabrina, Kasherman, Maria, Davila, Raul Ayala, Harris, Lucy, Green, Kathryn, Piper, Hannah, Parton, Robert G., Thor, Stefan, Cooper, Helen M., and Piper, Michael (2022). Hydrocephalus in Nfix−/− mice is underpinned by changes in ependymal cell physiology. Cells 11 (15) 2377 1-27. https://doi.org/10.3390/cells11152377
Pkd1 and Wnt5a genetically interact to control lymphatic vascular morphogenesis in mice
Chau, Tevin CY., Baek, Sungmin, Coxam, Baptiste, Skoczylas, Renae, Rondon‐Galeano, Maria, Bower, Neil I., Wainwright, Elanor N., Stacker, Steven A., Cooper, Helen M., Koopman, Peter A., Lagendijk, Anne K., Harvey, Natasha L., François, Mathias, and Hogan, Benjamin M. (2021). Pkd1 and Wnt5a genetically interact to control lymphatic vascular morphogenesis in mice. Developmental Dynamics 251 (2) dvdy.390 336-349. https://doi.org/10.1002/dvdy.390
Conservation of neural progenitor identity and the emergence of neocortical neuronal diversity
Shohayeb, Belal, Muzar, Zukhrofi, and Cooper, Helen M. (2021). Conservation of neural progenitor identity and the emergence of neocortical neuronal diversity. Seminars in Cell and Developmental Biology 118 4-13. https://doi.org/10.1016/j.semcdb.2021.05.024
DCC regulates astroglial development essential for telencephalic morphogenesis and corpus callosum formation
Morcom, Laura, Gobius, Ilan, Marsh, Ashley P. L., Suárez, Rodrigo, Lim, Jonathan W. C., Bridges, Caitlin, Ye, Yunan, Fenlon, Laura R., Zagar, Yvrick, Douglass, Amelia M., Donahoo, Amber-Lee, Fothergill, Thomas, Shaikh, Samreen, Kozulin, Peter, Edwards, Timothy J., Cooper, Helen M., IRC5 Consortium, Sherr, Elliott H., Chédotal, Alain, Leventer, Richard J., Lockhart, Paul J., and Richards, Linda J. (2021). DCC regulates astroglial development essential for telencephalic morphogenesis and corpus callosum formation. eLife 10 e61769 1-35. https://doi.org/10.7554/eLife.61769
Mosaic synapses in epilepsy
Shohayeb, Belal and Cooper, Helen M. (2021). Mosaic synapses in epilepsy. Science 372 (6539) 235-236. https://doi.org/10.1126/science.abh3555
Mechanisms of cortical development: From the embryo to adulthood
Cooper, Helen M. and Flores, Cecilia (2021). Mechanisms of cortical development: From the embryo to adulthood. Seminars in Cell and Developmental Biology 118 1-3. https://doi.org/10.1016/j.semcdb.2021.08.012
The role of lipids in ependymal development and the modulation of adult neural stem cell function during aging and disease
Harkins, Danyon, Cooper, Helen M., and Piper, Michael (2020). The role of lipids in ependymal development and the modulation of adult neural stem cell function during aging and disease. Seminars in Cell and Developmental Biology 112 61-68. https://doi.org/10.1016/j.semcdb.2020.07.018
Dopamine axon targeting in the nucleus accumbens in adolescence requires netrin-1
Cuesta, Santiago, Nouel, Dominique, Reynolds, Lauren M., Morgunova, Alice, Torres-Berrío, Angélica, White, Amanda, Hernandez, Giovanni, Cooper, Helen M., and Flores, Cecilia (2020). Dopamine axon targeting in the nucleus accumbens in adolescence requires netrin-1. Frontiers in Cell and Developmental Biology 8 487 487. https://doi.org/10.3389/fcell.2020.00487
Draxin-mediated regulation of granule cell progenitor differentiation in the postnatal hippocampal dentate gyrus
Tawarayama, Hiroshi, Yamada, Hirohisa, Amin, Ruhul, Morita-Fujimura, Yuiko, Cooper, Helen M, Shinmyo, Yohei, Tanaka, Hideaki, and Ikawa, Shuntaro (2020). Draxin-mediated regulation of granule cell progenitor differentiation in the postnatal hippocampal dentate gyrus. Neuroscience 431 184-192. https://doi.org/10.1016/j.neuroscience.2020.02.005
Adherens junctions: guardians of cortical development
Veeraval, Lenin, O’Leary, Conor J., and Cooper, Helen M. (2020). Adherens junctions: guardians of cortical development. Frontiers in Cell and Developmental Biology 8 6 6. https://doi.org/10.3389/fcell.2020.00006
WNT5a regulates epithelial morphogenesis in the developing choroid plexus
Langford, Michael B., O'Leary, Conor J., Veeraval, Lenin, White, Amanda, Lanoue, Vanessa, and Cooper, Helen M. (2020). WNT5a regulates epithelial morphogenesis in the developing choroid plexus. Cerebral Cortex 30 (6) 3617-3631. https://doi.org/10.1093/cercor/bhz330
Loss of Neogenin1 in human colorectal carcinoma cells causes a partial EMT and wound-healing response
Chaturvedi, Vishal, Fournier-Level, Alexandre, Cooper, Helen M., and Murray, Michael J. (2019). Loss of Neogenin1 in human colorectal carcinoma cells causes a partial EMT and wound-healing response. Scientific Reports 9 (1) 4110 4110. https://doi.org/10.1038/s41598-019-40886-y
Branching mechanisms shaping dendrite architecture
Lanoue, Vanessa and Cooper, Helen M. (2019). Branching mechanisms shaping dendrite architecture. Developmental Biology 451 (1) 16-24. https://doi.org/10.1016/j.ydbio.2018.12.005