Group Leader
Molecular adaptations in neurodevelopment and neurodegeneration
The lab examines alterations in key molecular regulators involved in neurodevelopmental and neurodegenerative disorders such as autism and Parkinson’s disease. This research ultimately aims to detect early signs of neuronal dysfunction to restore normal brain activity to alleviate or prevent consequent symptoms.
The lab takes advantage of a multi-disciplinary approach, employing state-of-the-art molecular biology, genetics, in vitro/in vivo imaging and electrophysiological techniques combined to behavioural assessments.
Our Research Focus
Interneuron Development & Diversity
- Identify the molecular determinants that generate the remarkable diversity of inhibitory neurons in the mammalian brain.
Neuronal Adaptation & Circuit Balance
- How interneurons tune their activity in response to environmental and network demands.
Mechanisms of Brain Disorders
- How alterations in key molecular regulators contribute to conditions such as autism, schizophrenia, and Parkinson’s disease.
Latest News
- 18 June 2025
Latest Media
Podcast: What interneurons and their connections can teach us about autism
In this conversation, Nathalie explains:
- What mouse models teach us about the condition
- How early brain changes may lead to autism
- The mechanisms common to autism and schizophrenia
Study shows heightened sensitivity to PTSD in autism