Vukovic publications
Convergent evolution of scavenger cell development at brain borders
Gaudi, Andrea U., Meier, Michelle, Baltaci, Oguzhan F., Chowdhary, Sayali, Tulenko, Frank J., Dudczig, Stefanie, Stamatis, Sebastian-Alexander, Paterson, Scott, Yu, Hujun, Galeano, Maria Cristina Rondon, Mason, Elizabeth, Miles, Lee B., Bryson-Richardson, Robert J., Pask, Andrew J., Vukovic, Jana, Lagendijk, Anne K., Smith, Kelly A., Kaslin, Jan, Harrison, Michael RM, Currie, Peter D., Bower, Neil I., and Hogan, Benjamin M. (2026). Convergent evolution of scavenger cell development at brain borders. Nature 651 (8106) 743-751. https://doi.org/10.1038/s41586-025-10003-3
Microglia Gp130 Signaling Attenuates Tissue Damage and Functional Deficits Following Ischemia-Reperfusion Stroke Injury
Kim, Seung Jae, Gonzales, Maryanne, Xu, Yi, Featherstone, Felix, and Vukovic, Jana (2025). Microglia Gp130 Signaling Attenuates Tissue Damage and Functional Deficits Following Ischemia-Reperfusion Stroke Injury. Brain & Brain pet 2025, Suzhou, China, 9-12 May 2025. London, United Kingdom: SAGE Publications.
Melatonin’s role in the timing of sleep onset is conserved in nocturnal mice
Kim, Pureum, Garner, Nicholas, Tatkovic, Annaleis, Parsons, Rex, Chunduri, Prasad, Vukovic, Jana, Piper, Michael, Pfeffer, Martina, Weiergräber, Marco, Oster, Henrik, and Rawashdeh, Oliver (2024). Melatonin’s role in the timing of sleep onset is conserved in nocturnal mice. npj Biological Timing and Sleep 1 (1) 13 1-13. https://doi.org/10.1038/s44323-024-00013-1
Featured Cover
Chauquet, Solal, Willis, Emily F., Grice, Laura, Harley, Samuel B. R., Powell, Joseph E., Wray, Naomi R., Nguyen, Quan, Ruitenberg, Marc J., Shah, Sonia, and Vukovic, Jana (2024). Featured Cover. Aging Cell 23 (7) . https://doi.org/10.1111/acel.14279
Exercise rejuvenates microglia and reverses T cell accumulation in the aged female mouse brain
Chauquet, Solal, Willis, Emily F., Grice, Laura, Harley, Samuel B. R., Powell, Joseph E., Wray, Naomi R., Nguyen, Quan, Ruitenberg, Marc J., Shah, Sonia, and Vukovic, Jana (2024). Exercise rejuvenates microglia and reverses T cell accumulation in the aged female mouse brain. Aging Cell 23 (7) e14172 e14172. https://doi.org/10.1111/acel.14172
CSF1R inhibition promotes neuroinflammation and behavioural deficits during graft-versus-host disease in mice
Adams, Rachael C., Carter-Cusack, Dylan, Llanes, Genesis T., Hunter, Christopher R., Vinnakota, Janaki Manoja, Ruitenberg, Marc J., Vukovic, Jana, Bertolino, Patrick, Chand, Kirat K., Wixey, Julie A., Nayler, Samuel P., Hill, Geoffrey R., Furlan, Scott N., Zeiser, Robert, and MacDonald, Kelli P.A. (2024). CSF1R inhibition promotes neuroinflammation and behavioural deficits during graft-versus-host disease in mice. Blood Journal 143 (10) 912-929. https://doi.org/10.1182/blood.2023022040
A convergent evolutionary pathway attenuating cellulose production drives enhanced virulence of some bacteria
Nhu, Nguyen Thi Khanh, Rahman, M. Arifur, Goh, Kelvin G. K., Kim, Seung Jae, Phan, Minh-Duy, Peters, Kate M., Alvarez-Fraga, Laura, Hancock, Steven J., Ravi, Chitra, Kidd, Timothy J., Sullivan, Matthew J., Irvine, Katharine M., Beatson, Scott A., Sweet, Matthew J., Irwin, Adam D., Vukovic, Jana, Ulett, Glen C., Hasnain, Sumaira Z., and Schembri, Mark A. (2024). A convergent evolutionary pathway attenuating cellulose production drives enhanced virulence of some bacteria. Nature Communications 15 (1) 1441 1441. https://doi.org/10.1038/s41467-024-45176-4
ROCK2 regulates microglia proliferation and neuronal survival after traumatic brain injury
Willis, Emily F., Kim, Seung Jae, Chen, Wei, Nyuydzefe, Melanie, MacDonald, Kelli P.A., Zanin-Zhorov, Alexandra, Ruitenberg, Marc J., and Vukovic, Jana (2024). ROCK2 regulates microglia proliferation and neuronal survival after traumatic brain injury. Brain, Behavior, and Immunity 117 181-194. https://doi.org/10.1016/j.bbi.2024.01.004
CSF-1R inhibitor PLX3397 attenuates peripheral and brain chronic GVHD and improves functional outcomes in mice
Shaikh, Samreen N., Willis, Emily F., Dierich, Max, Xu, Yi, Stuart, Samuel J. S., Gobe, Glenda C., Bashaw, Abate A., Rawashdeh, Oliver, Kim, Seung Jae, and Vukovic, Jana (2023). CSF-1R inhibitor PLX3397 attenuates peripheral and brain chronic GVHD and improves functional outcomes in mice. Journal of Neuroinflammation 20 (1) 300 300. https://doi.org/10.1186/s12974-023-02984-7
Robust mapping of spatiotemporal trajectories and cell–cell interactions in healthy and diseased tissues
Pham, Duy, Tan, Xiao, Balderson, Brad, Xu, Jun, Grice, Laura F., Yoon, Sohye, Willis, Emily F., Tran, Minh, Lam, Pui Yeng, Raghubar, Arti, Kalita-de Croft, Priyakshi, Lakhani, Sunil, Vukovic, Jana, Ruitenberg, Marc J., and Nguyen, Quan H. (2023). Robust mapping of spatiotemporal trajectories and cell–cell interactions in healthy and diseased tissues. Nature Communications 14 (1) 7739 1-25. https://doi.org/10.1038/s41467-023-43120-6
CSF1R inhibition promotes neuroinflammation and behavioural deficits during graftversus-host disease in mice
Adams, Rachael C., Carter-Cusack, Dylan, Llanes, Genesis T., Hunter, Christopher R., Vinnakota, Janaki Manoja, Ruitenberg, Marc, Vukovic, Jana, Bertolino, Patrick, Chand, Kirat K., Wixey, Julie A., Nayler, Samuel P., Hill, Geoffrey R., Furlan, Scott N., Zeiser, Robert, and MacDonald, Kelli P. A. (2023). CSF1R inhibition promotes neuroinflammation and behavioural deficits during graftversus-host disease in mice. 65th Annual Meeting of the American-Society-of-Hematology (ASH), San Diego, CA, United States, 9-12 December 2023. Washington, DC, United States: American Society of Hematology.https://doi.org/10.1182/blood-2023-184841
Current animal models of extracorporeal cardiopulmonary resuscitation: a scoping review
Ijuin, Shinichi, Liu, Keibun, Gill, Denzil, Kyun Ro, Sun, Vukovic, Jana, Ishihara, Satoshi, Belohlavek, Jan, Li Bassi, Gianluigi, Suen, Jacky Y., and Fraser, John F. (2023). Current animal models of extracorporeal cardiopulmonary resuscitation: a scoping review. Resuscitation Plus 15 100426 1-9. https://doi.org/10.1016/j.resplu.2023.100426
Intravenous immunoglobulin (IVIG) promotes brain repair and improves cognitive outcomes after traumatic brain injury in a FcγRIIB receptor-dependent manner
Willis, Emily F., Gillespie, Ellen R., Guse, Kirsten, Zuercher, Adrian W., Käsermann, Fabian, Ruitenberg, Marc J., and Vukovic, Jana (2023). Intravenous immunoglobulin (IVIG) promotes brain repair and improves cognitive outcomes after traumatic brain injury in a FcγRIIB receptor-dependent manner. Brain, Behavior, and Immunity 109 37-50. https://doi.org/10.1016/j.bbi.2022.12.018
Donor bone marrow-derived macrophage MHC II drives neuroinflammation and altered behaviour during chronic GVHD in mice
Adams, Rachael C, Carter-Cusack, Dylan, Shaikh, Samreen N, Llanes, Genesis T, Johnston, Rebecca L, Quaife-Ryan, Gregory, Boyle, Glen M, Koufariotis, Lambros T, Möller, Andreas, Blazar, Bruce R., Vukovic, Jana, and MacDonald, Kelli PA (2022). Donor bone marrow-derived macrophage MHC II drives neuroinflammation and altered behaviour during chronic GVHD in mice. Blood 139 (9) 1389-1408. https://doi.org/10.1182/blood.2021011671
An exercise ‘sweet spot’ reverses cognitive deficits of ageing by growth hormone-induced neurogenesis
Blackmore, Daniel G., Steyn, Frederik J., Carlisle, Alison, O’Keeffe, Imogen, Vien, King-Year, Zhou, Xiaoqing, Leiter, Odette, Jhaveri, Dhanisha, Vukovic, Jana, Waters, Michael J., and Bartlett, Perry F. (2021). An exercise ‘sweet spot’ reverses cognitive deficits of ageing by growth hormone-induced neurogenesis. iScience 24 (11) 103275 1-25. https://doi.org/10.1016/j.isci.2021.103275
Selective ablation of BDNF from microglia reveals novel roles in self-renewal and hippocampal neurogenesis
Harley, Samuel B. R., Willis, Emily F., Shaikh, Samreen N., Blackmore, Daniel G., Sah, Pankaj, Ruitenberg, Marc J., Bartlett, Perry F., and Vukovic, Jana (2021). Selective ablation of BDNF from microglia reveals novel roles in self-renewal and hippocampal neurogenesis. The Journal of Neuroscience 41 (19) 4172-4186. https://doi.org/10.1523/jneurosci.2539-20.2021
Protocol for brain-wide or region-specific microglia depletion and repopulation in adult mice
Willis, Emily F. and Vukovic, Jana (2020). Protocol for brain-wide or region-specific microglia depletion and repopulation in adult mice. STAR protocols 1 (3) 100211 100211. https://doi.org/10.1016/j.xpro.2020.100211
Exercise reverses learning deficits induced by hippocampal injury by promoting neurogenesis
Codd, Lavinia N., Blackmore, Daniel G., Vukovic, Jana, and Bartlett, Perry F. (2020). Exercise reverses learning deficits induced by hippocampal injury by promoting neurogenesis. Scientific Reports 10 (1) 19269 19269. https://doi.org/10.1038/s41598-020-76176-1
stLearn integrating spatial location, tissue morphology and gene expression to find cell types, cell-cell interactions and spatial trajectories within undissociated tissues
Pham, Duy, Tan, Xiao, Xu, Jun, Grice, Laura F., Lam, Pui Yeng, Raghubar, Arti, Vukovic, Jana, Ruitenberg, Marc J., and Nguyen, Quan (2020). stLearn integrating spatial location, tissue morphology and gene expression to find cell types, cell-cell interactions and spatial trajectories within undissociated tissues. Biorxiv 1-18. https://doi.org/10.1101/2020.05.31.125658v1
Repopulating Microglia Promote Brain Repair in an IL-6-Dependent Manner
Willis, Emily F., MacDonald, Kelli P. A., Nguyen, Quan H., Garrido, Adahir Labrador, Gillespie, Ellen R., Harley, Samuel B. R., Bartlett, Perry F., Schroder, Wayne A., Yates, Abi G., Anthony, Daniel C., Rose-John, Stefan, Ruitenberg, Marc J., and Vukovic, Jana (2020). Repopulating Microglia Promote Brain Repair in an IL-6-Dependent Manner. Cell 180 (5) 833-846.e16. https://doi.org/10.1016/j.cell.2020.02.013