Eyles publications
Developmental-vitamin D deficiency epigenetically regulates cell cycling genes in the embryonic mesencephalon via DNA methylation
Cui, Xiaoying, Pertile, Renata Aparecida Nedel, Alexander, Suzy, Ali, Asad, and Eyles, Darryl (2026). Developmental-vitamin D deficiency epigenetically regulates cell cycling genes in the embryonic mesencephalon via DNA methylation. Journal of Steroid Biochemistry and Molecular Biology 261 107015 107015. https://doi.org/10.1016/j.jsbmb.2026.107015
“Intranasal clozapine sol-gel formulation induces an antipsychotic effect at a fraction of a comparable oral therapeutic dose”
Eyles, DW, Parekh, HS, Alexander, S., Pandey, P., Siskind, D., Ali, M., Langguth, M., Lohman, R., and Cui, X. (2026). “Intranasal clozapine sol-gel formulation induces an antipsychotic effect at a fraction of a comparable oral therapeutic dose”. Translational Psychiatry . https://doi.org/10.1038/s41398-026-04061-y
EPITRANSCRIPTOMIC REGULATION OF STRIATAL FUNCTION: A NEW NEUROBIOLOGY OF SCHIZOPHRENIA?
Cui, X, Srivastav, S, and Eyles, D (2025). 630. EPITRANSCRIPTOMIC REGULATION OF STRIATAL FUNCTION: A NEW NEUROBIOLOGY OF SCHIZOPHRENIA?. 36th CINP World Congress Neuropsychopharmacology - CINP-AsCNP 2025 Joint Congress, Melbourne, VIC, Australia, 15 - 18 June 2025. Oxford, United Kingdom: Oxford University Press.https://doi.org/10.1093/ijnp/pyaf052.156
Vitamin D differentiates dopamine neurons in vitro, increasing neurite architecture, dopamine release and expression of relevant synaptic proteins
Cui, Xiaoying, Pertile, Renata Aparecida Nedel, Raman, Vanshika, and Eyles, Darryl (2025). Vitamin D differentiates dopamine neurons in vitro, increasing neurite architecture, dopamine release and expression of relevant synaptic proteins. Journal of Steroid Biochemistry and Molecular Biology 247 106681 1-6. https://doi.org/10.1016/j.jsbmb.2025.106681
Absence of association between maternal adverse events and long-term gut microbiome outcomes in the Australian Autism Biobank
Vasileva, Svetlina, Yap, Chloe X., Whitehouse, Andrew J. O., Gratten, Jacob, and Eyles, Darryl (2024). Absence of association between maternal adverse events and long-term gut microbiome outcomes in the Australian Autism Biobank. Brain, Behavior, and Immunity - Health 39 100814 100814. https://doi.org/10.1016/j.bbih.2024.100814
Neonatal vitamin D and associations with longitudinal changes of eczema up to 25 years of age
Zeng, Rong, Lodge, Caroline J., Koplin, Jennifer J., Lopez, Diego J., Erbas, Bircan, Abramson, Michael J., Eyles, Darryl, Ponsonby, Anne-Louise, Wjst, Matthias, Allen, Katrina, Dharmage, Shyamali C., and Lowe, Adrian J. (2024). Neonatal vitamin D and associations with longitudinal changes of eczema up to 25 years of age. Nutrients 16 (9) 1303 1303. https://doi.org/10.3390/nu16091303
Associations of the gut microbiome with treatment resistance in schizophrenia
Vasileva, Svetlina S., Yang, Yuanhao, Baker, Andrea, Siskind, Dan, Gratten, Jacob, and Eyles, Darryl (2024). Associations of the gut microbiome with treatment resistance in schizophrenia. JAMA Psychiatry 81 (3) 292-302. https://doi.org/10.1001/jamapsychiatry.2023.5371
Mixture of air pollution, brominated flame retardants, polychlorinated biphenyls, per- and polyfluoroalkyl substances, and organochlorine pesticides in relation to vitamin D concentrations in pregnancy
Berger, Kimberly, Bradshaw, Patrick T., Poon, Victor, Kharrazi, Marty, Eyles, Darryl, Ashwood, Paul, Lyall, Kristen, Volk, Heather E., Ames, Jenn, Croen, Lisa A., Windham, Gayle C., and Pearl, Michelle (2024). Mixture of air pollution, brominated flame retardants, polychlorinated biphenyls, per- and polyfluoroalkyl substances, and organochlorine pesticides in relation to vitamin D concentrations in pregnancy. Environmental Pollution 340 (Pt 2) 122808 1-12. https://doi.org/10.1016/j.envpol.2023.122808
TRS-BIOME
Eyles, Darryl, Vasileva, Svetlina, Siskind, Dan, Alexander, Suzy, Gratten, Jake, Ko, Pauline, and Vasileva, Svetlina(2024). TRS-BIOME. The University of Queensland. Data Collection.https://doi.org/10.48610/23fd2eb
Vitamin D, brain development and function
Eyles, Darryl, Cui, Xiaoying, and McGrath, John J. (2024). Vitamin D, brain development and function. Feldman and Pike' s vitamin D: volume one: biochemistry, physiology and diagnostics. Edited by Martin Hewison, Roger Bouillon, Edward Giovannucci, David Goltzman, Mark Meyer, and JoEllen Welsh. London, United Kingdom: Elsevier.537-562.https://doi.org/10.1016/b978-0-323-91386-7.00040-4
Increasing dopamine synthesis in nigrostriatal circuits increases phasic dopamine release and alters dorsal striatal connectivity: implications for schizophrenia
Srivastav, Sunil, Cui, Xiaoying, Varela, Roger Bitencourt, Kesby, James P., and Eyles, Darryl (2023). Increasing dopamine synthesis in nigrostriatal circuits increases phasic dopamine release and alters dorsal striatal connectivity: implications for schizophrenia. Schizophrenia 9 (1) 69 69. https://doi.org/10.1038/s41537-023-00397-2
Vitamin D: a potent regulator of dopaminergic neuron differentiation and function
Pertile, Renata Aparecida Nedel, Brigden, Rachel, Raman, Vanshika, Cui, Xiaoying, Du, Zilong, and Eyles, Darryl (2023). Vitamin D: a potent regulator of dopaminergic neuron differentiation and function. Journal of Neurochemistry 166 (5) 779-789. https://doi.org/10.1111/jnc.15829
Tamang, Man Kumar, Ali, Asad, Pertile, Renata Nedel, Cui, Xiaoying, Alexander, Suzy, Nitert, Marloes Dekker, Palmieri, Chiara and Eyles, Darryl (2023). Developmental vitamin D-deficiency produces autism-relevant behaviours and gut-health associated alterations in a rat model. Translational Psychiatry, 13 (1) 204. doi: 10.1038/s41398-023-02513-3
Developmental vitamin D-deficiency produces autism-relevant behaviours and gut-health associated alterations in a rat model
Tamang, Man Kumar, Ali, Asad, Pertile, Renata Nedel, Cui, Xiaoying, Alexander, Suzy, Nitert, Marloes Dekker, Palmieri, Chiara, and Eyles, Darryl (2023). Developmental vitamin D-deficiency produces autism-relevant behaviours and gut-health associated alterations in a rat model. Translational Psychiatry 13 (1) 204 1-12. https://doi.org/10.1038/s41398-023-02513-3
Animal models of relevance to the schizophrenia prodrome
Petty, Alice, Howes, Oliver, and Eyles, Darryl (2023). Animal models of relevance to the schizophrenia prodrome. Biological Psychiatry Global Open Science 3 (1) 22-32. https://doi.org/10.1016/j.bpsgos.2021.12.001
Vitamin D and the central nervous system: causative and preventative mechanisms in brain disorders
Cui, Xiaoying and Eyles, Darryl W. (2022). Vitamin D and the central nervous system: causative and preventative mechanisms in brain disorders. Nutrients 14 (20) 4353 1-20. https://doi.org/10.3390/nu14204353
Mixture analysis of air pollution and endocrine disrupting chemicals in relation to Vitamin D concentrations in pregnancy
Berger, Kimberly, Poon, Victor, Kharrazi, Marty, Eyles, Darryl, Lyall, Kristen, Volk, Heather E., Croen, Lisa A., Windham, Gayle, and Pearl, Michelle (2022). Mixture analysis of air pollution and endocrine disrupting chemicals in relation to Vitamin D concentrations in pregnancy. ISEE 2022: 34th Annual Conference of the International Society of Environmental Epidemiology, Athens, Greece, 18-21 September 2022. Research Triangle Park, NC United States: National Institute of Environmental Health Sciences.https://doi.org/10.1289/isee.2022.o-op-271
Developmental vitamin D-deficiency increases the expression of microRNAs involved in dopamine neuron development
Aparecida Nedel Pertile, Renata, Kiltschewskij, Dylan, Geaghan, Michael, Barnett, Michelle, Cui, Xiaoying, Cairns, Murray J., and Eyles, Darryl (2022). Developmental vitamin D-deficiency increases the expression of microRNAs involved in dopamine neuron development. Brain Research 1789 147953 147953. https://doi.org/10.1016/j.brainres.2022.147953
Prenatal hypoxia alters the early ontogeny of dopamine neurons
Brandon, Anastasia, Cui, Xiaoying, Luan, Wei, Ali, Asad Amanat, Pertile, Renata Aparecida Nedel, Alexander, Suzanne Adele, and Eyles, Darryl Walter (2022). Prenatal hypoxia alters the early ontogeny of dopamine neurons. Translational Psychiatry 12 (1) 238 238. https://doi.org/10.1038/s41398-022-02005-w
Does the gut microbiome mediate antipsychotic-induced metabolic side effects in schizophrenia?
Vasileva, Svetlina S., Tucker, Jack, Siskind, Dan, and Eyles, Darryl (2022). Does the gut microbiome mediate antipsychotic-induced metabolic side effects in schizophrenia?. Expert Opinion on Drug Safety 21 (5) 1-15. https://doi.org/10.1080/14740338.2022.2042251
Association between circulating 25-hydroxyvitamin D concentrations and hip replacement for osteoarthritis: a prospective cohort study
Hussain, Sultana Monira, Wang, Yuanyuan, Heath, Alicia K., Giles, Graham G., English, Dallas R., Eyles, Darryl W., Williamson, Elizabeth J., Graves, Stephen E., Wluka, Anita E., and Cicuttini, Flavia M. (2021). Association between circulating 25-hydroxyvitamin D concentrations and hip replacement for osteoarthritis: a prospective cohort study. BMC Musculoskeletal Disorders 22 (1) 887 887. https://doi.org/10.1186/s12891-021-04779-4