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Dr Anson Tan

Postdoctoral Research Fellow
Queensland Brain Institute
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Researcher biography

Anson received his PhD in 2018 from the University of Melbourne and continued his study on the molecular basis of membrane trafficking and protein sorting in the Golgi with Professor Paul Gleeson. In 2020, Dr Tan joined the Queensland Brain Institute at the University of Queensland, where he is currently a Postdoctorial Research Fellow at the Clem Jones Centre for Ageing Dementia Research. His research at the Anggono laboratory aims to understand the molecular mechanisms of membrane trafficking in neurons, processes that are essential for synaptic transmission, plasticity, learning and memory, and how their dysregulation lead to neurodegenerative diseases and neuropsychiatric disorders. Dr Tan was recently awarded the UQ Postdoctoral Researcher Retention Fellowship (University of Queensland, 2022).

Publications

Journal Articles (6)

Journal Articles

Yong, Xuan Ling Hilary, Zhang, Lingrui, Yang, Liming, Chen, Xiumin, Tan, Jing Zhi Anson, Yu, Xiaojun, Chandra, Mintu, Livingstone, Emma, Widagdo, Jocelyn, Vieira, Marta M., Roche, Katherine W., Lynch, Joseph W., Keramidas, Angelo, Collins, Brett M. and Anggono, Victor (2021). Regulation of NMDA receptor trafficking and gating by activity-dependent CaMKIIα phosphorylation of the GluN2A subunit. Cell Reports, 36 (1) 109338, 1-21. doi: 10.1016/j.celrep.2021.109338
Tan, Jing Zhi A., Fourriere, Lou, Wang, Jingqi, Perez, Franck, Boncompain, Gaelle and Gleeson, Paul A. (2020). Distinct anterograde trafficking pathways of BACE1 and amyloid precursor protein from the TGN and the regulation of amyloid-beta production. Molecular Biology of the Cell, 31 (1), 27-44. doi: 10.1091/mbc.E19-09-0487
Tan, Jing Zhi Anson and Gleeson, Paul Anthony (2019). Cargo Sorting at the trans-Golgi Network for Shunting into Specific Transport Routes: Role of Arf Small G Proteins and Adaptor Complexes. Cells, 8 (6), 531. doi: 10.3390/cells8060531
Tan, Jing Zhi A. and Gleeson, Paul A. (2019). The role of membrane trafficking in the processing of amyloid precursor protein and production of amyloid peptides in Alzheimer's disease. Biochimica Et Biophysica Acta-Biomembranes, 1861 (4), 697-712. doi: 10.1016/j.bbamem.2018.11.013
Tan, Jing Zhi A. and Gleeson, Paul A. (2019). The trans-Golgi network is a major site for alpha-secretase processing of amyloid precursor protein in primary neurons. Journal of Biological Chemistry, 294 (5), 1618-1631. doi: 10.1074/jbc.RA118.005222
Toh, Wei Hong, Tan, Jing Zhi A., Zulkefli, Khalisah L., Houghton, Fiona J. and Gleeson, Paul A. (2017). Amyloid precursor protein traffics from the Golgi directly to early endosomes in an Arl5b-and AP4-dependent pathway. Traffic, 18 (3), 159-175. doi: 10.1111/tra.12465