Book Chapter
Li, X. and Wei, W. (2017). Approaches to detecting DNA base modification in the brain. DNA modifications in the brain: Neuroepigenetic Regulation of Gene Expression. (pp. 27-41) edited by Timothy W. Bredy. London, United Kingdom: Academic Press. doi: 10.1016/B978-0-12-801596-4.00002-2
Journal Articles
Zhang, Jianjian, Li, Sirui, Fujimura, Miki, Lau, Tsz Yeung, Wu, Xiaolin, Hu, Miao, Zheng, Hanpei, Xu, Haibo, Zhao, Wenyuan, Li, Xiang and Chen, Jincao (2021). Hemodynamic analysis of the recipient parasylvian cortical arteries for predicting postoperative hyperperfusion during STA-MCA bypass in adult patients with moyamoya disease. Journal of Neurosurgery, 134 (1), 17-24. doi: 10.3171/2019.10.JNS191207
Ali, Asad Amanat, Cui, Xiaoying, Pertile, Renata Aparecida Nedel, Li, Xiang, Medley, Gregory, Alexander, Suzanne Adele, Whitehouse, Andrew J. O., McGrath, John J. and Eyles, Darryl Walter (2020). Developmental vitamin D deficiency increases foetal exposure to testosterone. Molecular Autisum, 11 (1) 96, 96. doi: 10.1186/s13229-020-00399-2
Chen, Min, Zhao, Qiong-Yi, Edson, Janette, Zhang, Zong Hong, Li, Xiang, Wei, Wei, Bredy, Timothy and Reutens, David C. (2020). Genome-wide microRNA profiling in brain and blood samples in a mouse model of epileptogenesis. Epilepsy Research, 166 106400, 106400. doi: 10.1016/j.eplepsyres.2020.106400
Marshall, Paul R., Zhao, Qiongyi, Li, Xiang, Wei, Wei, Periyakaruppiah, Ambika, Zajaczkowski, Esmi L., Leighton, Laura J., Madugalle, Sachithrani U., Basic, Dean, Wang, Ziqi, Yin, Jiayu, Liau, Wei-Siang, Gupte, Ankita, Walkley, Carl R. and Bredy, Timothy W. (2020). Dynamic regulation of Z-DNA in the mouse prefrontal cortex by the RNA-editing enzyme Adar1 is required for fear extinction. Nature Neuroscience, 23 (6), 718-729. doi: 10.1038/s41593-020-0627-5
Leighton, Laura J., Wei, Wei, Marshall, Paul R., Ratnu, Vikram Singh, Li, Xiang, Zajaczkowski, Esmi L., Spadaro, Paola A., Khandelwal, Nitin, Kumar, Arvind and Bredy, Timothy W. (2019). Disrupting the hippocampal Piwi pathway enhances contextual fear memory in mice. Neurobiology of Learning and Memory, 161, 202-209. doi: 10.1016/j.nlm.2019.04.002
Zou, Yichun, Gong, Pian, Zhao, Wenyuan, Zhang, Jianjian, Wu, Xiaolin, Xin, Can, Xiong, Zhongwei, Li, Zhengwei, Wu, Xiaohui, Wan, Qi, Li, Xiang and Chen, Jincao (2019). Quantitative iTRAQ-based proteomic analysis of piperine protected cerebral ischemia/reperfusion injury in rat brain. Neurochemistry International, 124, 51-61. doi: 10.1016/j.neuint.2018.12.010
Li, Xiang, Zhao, Qiongyi, Wei, Wei, Lin, Quan, Magnan, Christophe, Emami, Michael R., Wearick-Silva, Luis E., Viola, Thiago W., Marshall, Paul R., Yin, Jiayu, Madugalle, Sachithrani U., Wang, Ziqi, Nainar, Sarah, Vågbø, Cathrine Broberg, Leighton, Laura J., Zajaczkowski, Esmi L., Ke, Ke, Grassi-Oliveira, Rodrigo, Bjørås, Magnar, Baldi, Pierre F., Spitale, Robert C. and Bredy, Timothy W. (2019). The DNA modification N6-methyl-2’-deoxyadenosine (m6dA) drives activity-induced gene expression and is required for fear extinction. Nature Neuroscience, 22 (4), 534-544. doi: 10.1038/s41593-019-0339-x
Li, Xiang, Marshall, Paul R., Leighton, Laura J., Zajaczkowski, Esmi L., Wang, Ziqi, Madugalle, Sachithrani U., Yin, Jiayu, Bredy, Timothy W. and Wei, Wei (2019). The DNA repair-associated protein gadd45γ regulates the temporal coding of immediate early gene expression within the prelimbic prefrontal cortex and is required for the consolidation of associative fear memory. The Journal of Neuroscience, 39 (6), 970-983. doi: 10.1523/JNEUROSCI.2024-18.2018
Viola, Thiago Wendt, Wearick-Silva, Luis Eduardo, Creutzberg, Kerstin C., Kestering-Ferreira, Érika, Orso, Rodrigo, Centeno-Silva, Anderson, Albrechet-Souza, Lucas, Marshall, Paul R., Li, Xiang, Bredy, Timothy W., Riva, Marco A. and Grassi-Oliveira, Rodrigo (2019). Postnatal impoverished housing impairs adolescent risk-assessment and increases risk-taking: a sex-specific effect associated with histone epigenetic regulation of Crfr1 in the medial prefrontal cortex. Psychoneuroendocrinology, 99, 8-19. doi: 10.1016/j.psyneuen.2018.08.032
Ploense, Kyle L., Li, Xiang, Baker-Andresen, Danay, Carr, Amanda E., Woodward, Nick, Bagley, Jared, Szumlinski, Karen K., Bredy, Timothy W. and Kippin, Tod E. (2018). Prolonged-access to cocaine induces distinct Homer2 DNA methylation, hydroxymethylation, and transcriptional profiles in the dorsomedial prefrontal cortex of Male Sprague-Dawley rats. Neuropharmacology, 143, 299-305. doi: 10.1016/j.neuropharm.2018.09.029
Zajaczkowski, Esmi L., Zhao, Qiong-Yi, Zhang, Zong Hong, Li, Xiang, Wei, Wei, Marshall, Paul R., Leighton, Laura J., Nainar, Sarah, Feng, Chao, Spitale, Robert C. and Bredy, Timothy W. (2018). Bioorthogonal metabolic labeling of nascent RNA in neurons improves the sensitivity of transcriptome-wide profiling. ACS Chemical Neuroscience, 9 (7), 1858-1865. doi: 10.1021/acschemneuro.8b00197
Murphy, Conor P., Li, Xiang, Maurer, Verena, Oberhauser, Michael, Gstir, Ronald, Wearick-Silva, Luis Eduardo, Viola, Thiago Wendt, Schafferer, Simon, Grassi-Oliverira, Rodrigo, Whittle, Nigel, Huttenhofer, Alexander, Bredy, Timothy W. and Singewald, Nicolas (2017). MicroRNA-mediated rescue of fear extinction memory by miR-144-3p in extinction-impaired mice. Biological Psychiatry, 81 (12), 979-989. doi: 10.1016/j.biopsych.2016.12.021
Wearick-Silva, Luis Eduardo, Marshall, Paul, Viola, Thiago Wendt, Centeno-Silva, Anderson, de Azeredo, Lucas Araujo, Orso, Rodrigo, Li, Xiang, Donadio, Marcio V., Bredy, Timothy W. and Grassi-Oliveira, Rodrigo (2017). Running during adolescence rescues a maternal separation-induced memory impairment in female mice: Potential role of differential exon-specific BDNF expression. Developmental Psychobiology, 59 (2), 268-274. doi: 10.1002/dev.21487
Nguyen, Kim, Fazio, Michael, Kubota, Miles, Nainar, Sarah, Feng, Chao, Li, Xiang, Atwood, Scott X., Bredy, Timothy W. and Spitale, Robert C. (2017). Cell-selective bioorthogonal metabolic labeling of RNA. Journal of the American Chemical Society, 139 (6), 2148-2151. doi: 10.1021/jacs.6b11401
Viola, Thiago Wendt, Wearick-Silva, Luis Eduardo, De Azeredo, Lucas Araujo, Centeno-Silva, Anderson, Murphy, Conor, Marshall, Paul, Li, Xiang, Singewald, Nicolas, Garcia, Frederico, Bredy, Timothy W. and Grassi-Oliveira, Rodrigo (2016). Increased cocaine-induced conditioned place preference during periadolescence in maternally separated male BALB/c mice: the role of cortical BDNF, microRNA-212, and MeCP2. Psychopharmacology, 233 (17), 3279-3288. doi: 10.1007/s00213-016-4373-z
Baker-Andresen, Danay, Zhao, Qiongyi, Li, Xiang, Jupp, Bianca, Chesworth, Rose, Lawrence, Andrew J. and Bredy, Timothy (2015). Persistent variations in neuronal DNA methylation following cocaine self-administration and protracted abstinence in mice. Neuroepigenetics, 4, 1-11. doi: 10.1016/j.nepig.2015.10.001
Li, X., Baker-Andresen, D., Zhao, Q., Marshall, V. and Bredy, T. W. (2014). Methyl CpG Binding Domain Ultra-Sequencing: a novel method for identifying inter-individual and cell-type-specific variation in DNA methylation. Genes, Brain and Behavior, 13 (7), 721-731. doi: 10.1111/gbb.12150
Li, Xiang, Wei, Wei, Zhao, Qiong-Yi, Widagdo, Jocelyn, Baker-Andresen, Danay, Flavell, Charlotte R., D'Alessio, Ana, Zhang, Yi and Bredy, Timothy W. (2014). Neocortical Tet3-mediated accumulation of 5-hydroxymethylcytosine promotes rapid behavioral adaptation. Proceedings of the National Academy of Sciences, 111 (19), 7120-7125. doi: 10.1073/pnas.1318906111
Baker-Andresen, Danay, Flavell, Charlotte R., Li, Xiang and Bredy, Timothy W. (2013). Activation of BDNF signaling prevents the return of fear in female mice. Learning & Memory, 20 (5), 237-240. doi: 10.1101/lm.029520.112
Wei, Wei, Coelho, Carlos M., Li, Xiang, Marek, Roger, Yan, Shanzhi, Anderson, Shawn, Meyers, David, Mukherjee, Chandrani, Sbardella, Gianluca, Castellano, Sabrina, Milite, Ciro, Rotili, Dante, Mai, Antonello, Cole, Philip A., Sah, Pankaj, Kobor, Michael S. and Bredy, Timothy W. (2012). p300/CBP-associated factor selectively regulates the extinction of conditioned fear. Journal of Neuroscience, 32 (35), 11930-11941. doi: 10.1523/JNEUROSCI.0178-12.2012
Dudley, Kevin J., Li, Xiang, Kobor, Michael S., Kippin, Tod E. and Bredy, Timothy W. (2011). Epigenetic mechanisms mediating vulnerability and resilience to psychiatric disorders. Neuroscience and Biobehavioral Reviews, 35 (7), 1544-1551. doi: 10.1016/j.neubiorev.2010.12.016
Conference Papers
Ratnu, V., Li, X., Emami, M., Zhao, Q. -Y. and Bredy, T. (2015). Exploring the role of histone demethylase, UTX, in mediating sex differences in fear-related learning and memory. 25th Biennial Meeting of the International Society for Neurochemistry Jointly with the 13th Meeting of the Asian Pacific Society for Neurochemistry in Conjunction with the 35th Meeting of the Australasian Neuroscience Society, Cairns, QLD Australia, 23-27 August 2015. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/jnc.13188
Ploense, Kyle, Carr, Amanda, Baker-Andresen, Danay, Li, Xiang, Woodward, Nick, Sun, Yi, Bredy, Timothy and Kippin, Tod (2014). Prolonged Access to Cocaine Results in Distinct Epigenetic Changes in the Prefrontal Cortex. Experimental Biology 2014 Meeting, San Diego CA, United States, 26-30 April 2014. Bethesda, MD United States: Federation of American Societies for Experimental Biology.