Towards a mechanistic understanding of the emergence of positive psychotic symptoms
Prof Marta Garrido
Professor in Psychology
Melbourne School of Psychological Sciences
Towards a mechanistic understanding of the emergence of positive psychotic symptoms
Abstract:
Computational Psychiatry uses mathematical modelling with two major goals: 1) to build new AI-inspired psychiatric instruments to aid diagnosis, prognosis, and treatment; and 2) to understand the mechanisms underpinning aberrant experiences in people with a psychiatric condition. In this talk, I will present our recent contributions to the latter. I will show how we have empirically adjudicated between conflicting Bayesian models to explain the occurrence of altered perceptual experiences via top-down and bottom-up processing aberrancies across the continuum of psychosis.
Bio:
Professor Marta Garrido leads the Cognitive Neuroscience and Computational Psychiatry Laboratory, is a Chief Investigator on the ARC Centre of Excellence for Quantum Biotechnology and is the Director of the MEG facility at The University of Melbourne. Prof Garrido initially trained in Engineering Physics at the University of Lisbon and then did a PhD in Neuroscience at University College London. Prof Garrido has over 20 years of experience in the fields of human neuroscience, brain imaging (fMRI, DWI, MEG, EEG) and computational modelling. Her team seeks to understand how the brains of typical individuals and people with psychiatric conditions learn from experience and make decisions. To date, Prof Garrido has produced over 100 peer-reviewed publications, some in the world’s most prestigious journals including Science, Nature Neuroscience, Nature Mental Health, Nature Communications, Nature Methods, eLife, Current Biology, and PNAS. Her work has been cited over 8000 times, and she has secured over A$60 million in competitive funding as a chief investigator. The quality of her work has been recognised by prestigious awards including the Paxinos-Watson Prize and the Aubrey Lewis Award. Marta is a past Program Chair of the International Organisation for Human Brain Mapping and an advocate for Open Science.
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