Queensland Brain Institute

Walker Publications

Blood-brain crosstalk: the roles of neutrophils, platelets, and neutrophil extracellular traps in neuropathologies

Chou, Ming-Li, Babamale, Abdulkareem Olarewaju, Walker, Tara L., Cognasse, Fabrice, Blum, David, and Burnouf, Thierry (2023). Blood-brain crosstalk: the roles of neutrophils, platelets, and neutrophil extracellular traps in neuropathologies. Trends in Neurosciences 46 (9) 764-779. https://doi.org/10.1016/j.tins.2023.06.005

 
Platelet-derived exerkine CXCL4/platelet factor 4 rejuvenates hippocampal neurogenesis and restores cognitive function in aged mice

Leiter, Odette, Brici, David, Fletcher, Stephen J., Yong, Xuan Ling Hilary, Widagdo, Jocelyn, Matigian, Nicholas, Schroer, Adam B., Bieri, Gregor, Blackmore, Daniel G., Bartlett, Perry F., Anggono, Victor, Villeda, Saul A., and Walker, Tara L. (2023). Platelet-derived exerkine CXCL4/platelet factor 4 rejuvenates hippocampal neurogenesis and restores cognitive function in aged mice. Nature Communications 14 (1) 4375 1-20. https://doi.org/10.1038/s41467-023-39873-9

 

Erratum: Selenium mediates exercise-induced adult neurogenesis and reverses learning deficits induced by hippocampal injury and aging (Cell Metabolism (2022) 34(3) (408–423.e8), (S1550413122000055), (10.1016/j.cmet.2022.01.005))

Leiter, Odette, Zhuo, Zhan, Rust, Ruslan, Wasielewska, Joanna M., Grönnert, Lisa, Kowal, Susann, Overall, Rupert W., Adusumilli, Vijay S., Blackmore, Daniel G., Southon, Adam, Ganio, Katherine, McDevitt, Christopher A., Rund, Nicole, Brici, David, Mudiyan, Imesh Aththanayake, Sykes, Alexander M., Rünker, Annette E., Zocher, Sara, Ayton, Scott, Bush, Ashley I., Bartlett, Perry F., Hou, Sheng-Tao, Kempermann, Gerd, and Walker, Tara L. (2023). Erratum: Selenium mediates exercise-induced adult neurogenesis and reverses learning deficits induced by hippocampal injury and aging (Cell Metabolism (2022) 34(3) (408–423.e8), (S1550413122000055), (10.1016/j.cmet.2022.01.005)). Cell Metabolism 35 (6) 1085-1085. https://doi.org/10.1016/j.cmet.2023.04.019

 

Selenium supplementation provides potent neuroprotection following cerebral ischemia in mice

Zhuo, Zhan, Wang, Huimei, Zhang, Shuai, Bartlett, Perry F., Walker, Tara L., and Hou, Sheng-Tao (2023). Selenium supplementation provides potent neuroprotection following cerebral ischemia in mice. Journal of Cerebral Blood Flow and Metabolism 43 (7) 1060-1076. https://doi.org/10.1177/0271678x231156981

 

Protocol for three alternative paradigms to test spatial learning and memory in mice

Blackmore, Daniel G., Brici, David, and Walker, Tara L. (2022). Protocol for three alternative paradigms to test spatial learning and memory in mice. STAR Protocols 3 (3) 101500 1-16. https://doi.org/10.1016/j.xpro.2022.101500

          

The multifaceted role of platelets in mediating brain function

Burnouf, Thierry and Walker, Tara L. (2022). The multifaceted role of platelets in mediating brain function. Blood 140 (8) 815-827. https://doi.org/10.1182/blood.2022015970

 
Does a rare mutation in PTPRA contribute to the development of Parkinson's disease in an Australian multi-incident family?

Hill, Melissa A., Bentley, Steven R., Walker, Tara L., Mellick, George D., Wood, Stephen A., and Sykes, Alex M. (2022). Does a rare mutation in PTPRA contribute to the development of Parkinson's disease in an Australian multi-incident family?. PLoS One 17 (7 July) e0271499 1-17. https://doi.org/10.1371/journal.pone.0271499

 

Selenium mediates exercise-induced adult neurogenesis and reverses learning deficits induced by hippocampal injury and aging

Leiter, Odette, Zhuo, Zhan, Rust, Ruslan, Wasielewska, Joanna M., Grönnert, Lisa, Kowal, Susann, Overall, Rupert W., Adusumilli, Vijay S., Blackmore, Daniel G., Southon, Adam, Ganio, Katherine, McDevitt, Christopher A., Rund, Nicole, Brici, David, Aththanayake Mudiyan, Imesh , Sykes, Alexander M., Rünker, Annette E., Zocher, Sara, Ayton, Scott, Bush, Ashley I., Bartlett, Perry F., Hou, Sheng-Tao, Kempermann, Gerd, and Walker, Tara L. (2022). Selenium mediates exercise-induced adult neurogenesis and reverses learning deficits induced by hippocampal injury and aging. Cell Metabolism 34 (3) 408-423.e8. https://doi.org/10.1016/j.cmet.2022.01.005

 
Isolation and Culture of Adult Hippocampal Precursor Cells as Free-Floating Neurospheres

Rust, Ruslan and Walker, Tara L. (2022). Isolation and Culture of Adult Hippocampal Precursor Cells as Free-Floating Neurospheres. Methods in Molecular Biology. New York, NY United States: Humana Press Inc.33-44.https://doi.org/10.1007/978-1-0716-1783-0_3

 
Apple Peel and Flesh Contain Pro-neurogenic Compounds

Ichwan, Muhammad, Walker, Tara L., Nicola, Zeina, Ludwig-Müller, Jutta, Böttcher, Christoph, Overall, Rupert W., Adusumilli, Vijay S., Bulut, Merve, Sykes, Alex M., Hübner, Norbert, Ramirez-Rodriguez, Gerardo, Ortiz-López, Leonardo, Lugo-Hernández, Enrique A., and Kempermann, Gerd (2021). Apple Peel and Flesh Contain Pro-neurogenic Compounds. Stem Cell Reports 16 (3) 548-565. https://doi.org/10.1016/j.stemcr.2021.01.005

 
ROS dynamics delineate functional states of hippocampal neural stem cells and link to their activity-dependent exit from quiescence

Adusumilli, Vijay S., Walker, Tara L., Overall, Rupert W., Klatt, Gesa M., Zeidan, Salma A., Zocher, Sara, Kirova, Dilyana G., Ntitsias, Konstantinos, Fischer, Tim J., Sykes, Alex M., Reinhardt, Susanne, Dahl, Andreas, Mansfeld, Jörg, Rünker, Annette E., and Kempermann, Gerd (2021). ROS dynamics delineate functional states of hippocampal neural stem cells and link to their activity-dependent exit from quiescence. Cell Stem Cell 28 (2) 300-314.e6. https://doi.org/10.1016/j.stem.2020.10.019

 
Author Correction: Mast cells increase adult neural precursor proliferation and differentiation but this potential is not realized in vivo under physiological conditions (Scientific Reports, (2017), 7, 1, (17859), 10.1038/s41598-017-18184-2)

Wasielewska, Joanna M., Grönnert, Lisa, Rund, Nicole, Donix, Lukas, Rust, Ruslan, Sykes, Alexander M., Hoppe, Anja, Roers, Axel, Kempermann, Gerd, and Walker, Tara L. (2020). Author Correction: Mast cells increase adult neural precursor proliferation and differentiation but this potential is not realized in vivo under physiological conditions (Scientific Reports, (2017), 7, 1, (17859), 10.1038/s41598-017-18184-2). Scientific Reports 10 (1) 19816 . https://doi.org/10.1038/s41598-020-76589-y

 

Platelets in Neurodegenerative Conditions—Friend or Foe?

Leiter, Odette and Walker, Tara L. (2020). Platelets in Neurodegenerative Conditions—Friend or Foe?. Frontiers in Immunology 11 747 747. https://doi.org/10.3389/fimmu.2020.00747

 
Impaired adult hippocampal neurogenesis in a mouse model of familial hypercholesterolemia: a role for the LDL receptor and cholesterol metabolism in adult neural precursor cells

Engel, Daiane F., Grzyb, Anna N., de Oliveira, Jade, Poetzsch, Alexandra, Walker, Tara L., Brocardo, Patricia S., Kempermann, Gerd, and de Bem, Andreza F. (2019). Impaired adult hippocampal neurogenesis in a mouse model of familial hypercholesterolemia: a role for the LDL receptor and cholesterol metabolism in adult neural precursor cells. Molecular Metabolism 30 1-15. https://doi.org/10.1016/j.molmet.2019.09.002

 
Platelets: the missing link between the blood and brain?

Leiter, Odette and Walker, Tara L. (2019). Platelets: the missing link between the blood and brain?. Progress in Neurobiology 183 101695 101695. https://doi.org/10.1016/j.pneurobio.2019.101695

 
The systemic exercise-released chemokine lymphotactin/XCL1 modulates in vitro adult hippocampal precursor cell proliferation and neuronal differentiation

Leiter, Odette, Bernas, Stefanie N., Seidemann, Suse, Overall, Rupert W., Horenburg, Cindy, Kowal, Susann, Kempermann, Gerd, and Walker, Tara L. (2019). The systemic exercise-released chemokine lymphotactin/XCL1 modulates in vitro adult hippocampal precursor cell proliferation and neuronal differentiation. Scientific Reports 9 (1) 11831 11831. https://doi.org/10.1038/s41598-019-48360-5

 

MiR-135a1-5p is critical for exercise-induced adult neurogenesis

Pons-Espinal, Meritxell, Gasperini, Caterina, Marzi, Matteo J., Braccia, Clarissa, Armirotti, Andrea, Poetzsch, Alexandra, Walker, Tara L., Fabel, Klaus, Nicassio, Francesco, Kempermann, Gerd, and Tonelli, Davide De Pietri (2019). MiR-135a1-5p is critical for exercise-induced adult neurogenesis. Stem Cell Reports 12 (6) 1298-1312. https://doi.org/10.1016/j.stemcr.2019.04.020

 
Exercise-induced activated platelets increase adult hippocampal precursor proliferation and promote neuronal differentiation

Leiter, Odette, Seidemann, Suse, Overall, Rupert W., Ramasz, Beáta, Rund, Nicole, Schallenberg, Sonja, Grinenko, Tatyana, Wielockx, Ben, Kempermann, Gerd, and Walker, Tara L. (2019). Exercise-induced activated platelets increase adult hippocampal precursor proliferation and promote neuronal differentiation. Stem Cell Reports 12 (4) 667-679. https://doi.org/10.1016/j.stemcr.2019.02.009

 
T Lymphocytes Contribute to the Control of Baseline Neural Precursor Cell Proliferation but Not the Exercise-Induced Up-Regulation of Adult Hippocampal Neurogenesis

Walker, Tara L., Schallenberg, Sonja, Rund, Nicole, Groennert, Lisa, Rust, Ruslan, Kretschmer, Karsten, and Kempermann, Gerd (2018). T Lymphocytes Contribute to the Control of Baseline Neural Precursor Cell Proliferation but Not the Exercise-Induced Up-Regulation of Adult Hippocampal Neurogenesis. Frontiers in Immunology 9 2856 . https://doi.org/10.3389/fimmu.2018.02856

 
Mast cells increase adult neural precursor proliferation and differentiation but this potential is not realized in vivo under physiological conditions

Wasielewska, J. M., Grönnert, L., Rund, N., Donix, L., Rust, R., Sykes, A. M., Hoppe, A., Roers, A., Kempermann, G., and Walker, T. L. (2017). Mast cells increase adult neural precursor proliferation and differentiation but this potential is not realized in vivo under physiological conditions. Scientific Reports 7 (1) 17859 17859. https://doi.org/10.1038/s41598-017-18184-2

 
Isolation, culture and differentiation of adult hippocampal precursor cells

Bernas, Stefanie, Leiter, Odette, Walker, Tara, and Kempermann, Gerd (2017). Isolation, culture and differentiation of adult hippocampal precursor cells. Bio-protocol 7 (21) . https://doi.org/10.21769/bioprotoc.2603

 
p27kip1 is required for functionally relevant adult hippocampal neurogenesis in mice

Hoerster, Henrik, Garthe, Alexander, Walker, Tara L., Ichwan, Muhammad, Steiner, Barbara, Khan, Muhammad Amir, Lie, Dieter Chichung, Nicola, Zeina, Ramirez-Rodriguez, Gerardo, and Kempermann, Gerd (2017). p27kip1 is required for functionally relevant adult hippocampal neurogenesis in mice. Stem Cells 35 (3) 787-799. https://doi.org/10.1002/stem.2536

 
Different mechanisms must be considered to explain the increase in hippocampal neural precursor cell proliferation by physical activity

Overall, Rupert W., Walker, Tara L., Fischer, Tim J., Brandt, Moritz D., and Kempermann, Gerd (2016). Different mechanisms must be considered to explain the increase in hippocampal neural precursor cell proliferation by physical activity. Frontiers in Neuroscience 10 (AUG) 362 362. https://doi.org/10.3389/fnins.2016.00362

 
Lysophosphatidic acid receptor is a functional marker of adult hippocampal precursor cells

Walker, Tara L., Overall, Rupert W., Vogler, Steffen, Sykes, Alex M., Ruhwald, Susann, Lasse, Daniela, Ichwan, Muhammad, Fabel, Klaus, and Kempermann, Gerd (2016). Lysophosphatidic acid receptor is a functional marker of adult hippocampal precursor cells. Stem Cell Reports 6 (4) 552-565. https://doi.org/10.1016/j.stemcr.2016.03.002

 
A common language: how neuroimmunological cross talk regulates adult hippocampal neurogenesis

Leiter, Odette, Kempermann, Gerd, and Walker, Tara L. (2016). A common language: how neuroimmunological cross talk regulates adult hippocampal neurogenesis. Stem Cells International 2016 (1) 1681590 1-13. https://doi.org/10.1155/2016/1681590

 

Neural stem and progenitor cells in nervous system function and therapy

Walker, Tara, Huang, Jeffrey, and Young, Kaylene (2016). Neural stem and progenitor cells in nervous system function and therapy. Stem Cells International 2016 (1) 1890568 1890568-2. https://doi.org/10.1155/2016/1890568

 
Transplanted dentate progenitor cells show increased survival in an enriched environment but do not exert a neurotrophic effect on spatial memory within 2 weeks of engraftment

Jamal, Amanda L., Walker, Tara L., Nguyen, Amanda J. Waber, Berman, Robert F., Kempermann, Gerd, and Waldau, Ben (2015). Transplanted dentate progenitor cells show increased survival in an enriched environment but do not exert a neurotrophic effect on spatial memory within 2 weeks of engraftment. Cell Transplantation 24 (12) 2435-2448. https://doi.org/10.3727/096368915x687011