Walker Publications
Platelet concentrate-derived extracellular vesicles promote adult hippocampal neurogenesis
NyamErdene, Ariunjargal, Le, Nhi Thao Ngoc, Nebie, Ouada, Faivre, Emilie, Delila, Liling, Chou, Ming-Li, Lowe, Joshua R., Bantubungi, Kadiombo, Buée, Luc, Walker, Tara L., Blum, David, and Burnouf, Thierry (2026). Platelet concentrate-derived extracellular vesicles promote adult hippocampal neurogenesis. Biomaterials 328 123838 123838. https://doi.org/10.1016/j.biomaterials.2025.123838
Longitudinal associations between cardiorespiratory fitness and cognition in older adults: a 10-year-follow-up from the Generation 100 Study
Le, Ariana Nhung, Lydersen, Stian, Brissach, Daniel Estil, Håberg, Asta K., Walker, Tara L., Schaumberg, Mia, Berg, Helene Haugen, Stensvold, Dorthe Berg, and Tari, Atefe R. (2026). Longitudinal associations between cardiorespiratory fitness and cognition in older adults: a 10-year-follow-up from the Generation 100 Study. Medicine and Science in Sports and Exercise 58 (4) 704-712. https://doi.org/10.1249/mss.0000000000003903
Effects of 5-year exercise training on cognition in older adults: 10-years follow-up from the Generation 100 Study
Bakken, Jenny, Brissach, Daniel E., Ingeström, Emma M. L., Midttun, Sindre, Walker, Tara L., Stensvold, Dorthe, and Tari, Atefe R. (2025). Effects of 5-year exercise training on cognition in older adults: 10-years follow-up from the Generation 100 Study. Sports Medicine - Open 11 (1) 153 1-12. https://doi.org/10.1186/s40798-025-00956-0
Parvalbumin interneuron-dependent hippocampal neurogenesis evoked by prolonged rhythmic light flicker
Yan, Hai, Wang, Yunxuan, Deng, Xufan, Wu, Shiyu, Pan, Yifan, Du, Jun, Yu, Mei, Liu, Bo, Wang, Huimei, Zhang, Zhengyu, Chen, Jinghong, Chen, Shuifa, Wang, Yizheng, Walker, Tara, Bartlett, Perry, Ju, Jun, and Hou, Sheng-Tao (2025). Parvalbumin interneuron-dependent hippocampal neurogenesis evoked by prolonged rhythmic light flicker. Advanced Science 12 (37) e03017 1-19. https://doi.org/10.1002/advs.202503017
Neuroferroptosis in health and diseases
Lei, Peng, Walker, Tara, and Ayton, Scott (2025). Neuroferroptosis in health and diseases. Nature Reviews Neuroscience 26 (8) e689 497-511. https://doi.org/10.1038/s41583-025-00930-5
Neuroprotective mechanisms of exercise and the importance of fitness for healthy brain ageing
Tari, Atefe R., Walker, Tara L., Huuha, Aleksi M., Sando, Sigrid B., and Wisloff, Ulrik (2025). Neuroprotective mechanisms of exercise and the importance of fitness for healthy brain ageing. The Lancet 405 (10484) 1093-1118. https://doi.org/10.1016/S0140-6736(25)00184-9
Survival of the fittest? Peak oxygen uptake and all-cause mortality among older adults in Norway
Tari, Atefe R., Brissach, Daniel E., Ingeström, Emma M. L., Nauman, Javaid, Tyrell, Tristan, Foster, Carl, Radtke, Kimberley, Porcari, John P., Lydersen, Stian, Kaminsky, Leonard A., Myers, Jonathan, Walker, Tara L., Coombes, Jeff S., Stensvold, Dorthe, and Wisløff, Ulrik (2025). Survival of the fittest? Peak oxygen uptake and all-cause mortality among older adults in Norway. Progress in Cardiovascular Diseases 89 25-34. https://doi.org/10.1016/j.pcad.2024.11.004
The multifaceted role of XCL1 in health and disease
Syed, Muhammed, Dishman, Acacia F., Volkman, Brian F., and Walker, Tara L. (2025). The multifaceted role of XCL1 in health and disease. Protein Science 34 (2) e70032 1-10. https://doi.org/10.1002/pro.70032
Exerkines and brain rejuvenation
Leiter, Odette, Lowe, Joshua, Brici, David, and Walker, Tara L. (2024). Exerkines and brain rejuvenation. Alzheimer’s Association International Conference AAIC 2024, Philadelphia, PA United States, 28 July –1 August 2024. Hoboken, NJ United States: John Wiley & Sons.https://doi.org/10.1002/alz.083404
The relationship between adult hippocampal neurogenesis and cognitive impairment in Alzheimer's disease
Geigenmueller, Joris N., Tari, Atefe R., Wisloff, Ulrik, and Walker, Tara L. (2024). The relationship between adult hippocampal neurogenesis and cognitive impairment in Alzheimer's disease. Alzheimer's and Dementia 20 (10) 7369-7383. https://doi.org/10.1002/alz.14179
Lrp8 knockout mice fed a selenium-replete diet display subtle deficits in their spatial learning and memory function
Leiter, Odette, Brici, David, Aththanayake Mudiyan, Imesh, Choo, Fang Ming, Winkler, Anna, and Walker, Tara L. (2024). Lrp8 knockout mice fed a selenium-replete diet display subtle deficits in their spatial learning and memory function. Behavioral Neuroscience 138 (2) 125-141. https://doi.org/10.1037/bne0000585
The Active Place Avoidance (APA) test, an effective, versatile and repeatable spatial learning task for mice
Ali, Asad A., Walker, Tara L., and Blackmore, Daniel G. (2024). The Active Place Avoidance (APA) test, an effective, versatile and repeatable spatial learning task for mice. Journal of Visualized Experiments 2024 (204) e65935 1-14. https://doi.org/10.3791/65935
Stimulation of the muscarinic receptor M4 regulates neural precursor cell proliferation and promotes adult hippocampal neurogenesis
Madrid, Lidia I., Hafey, Katelyn, Bandhavkar, Saurabh, Bodea, Gabriela O., Jimenez-Martin, Javier, Milne, Michael, Walker, Tara L., Faulkner, Geoffrey J., Coulson, Elizabeth J., and Jhaveri, Dhanisha J. (2024). Stimulation of the muscarinic receptor M4 regulates neural precursor cell proliferation and promotes adult hippocampal neurogenesis. Development 151 (1) dev201835 1-13. https://doi.org/10.1242/dev.201835
Blood-brain crosstalk: the roles of neutrophils, platelets, and neutrophil extracellular traps in neuropathologies
Chou, Ming-Li, Babamale, Abdulkareem Olarewaju, Walker, Tara L., Cognasse, Fabrice, Blum, David, and Burnouf, Thierry (2023). Blood-brain crosstalk: the roles of neutrophils, platelets, and neutrophil extracellular traps in neuropathologies. Trends in Neurosciences 46 (9) 764-779. https://doi.org/10.1016/j.tins.2023.06.005
Platelet-derived exerkine CXCL4/platelet factor 4 rejuvenates hippocampal neurogenesis and restores cognitive function in aged mice
Leiter, Odette, Brici, David, Fletcher, Stephen J., Yong, Xuan Ling Hilary, Widagdo, Jocelyn, Matigian, Nicholas, Schroer, Adam B., Bieri, Gregor, Blackmore, Daniel G., Bartlett, Perry F., Anggono, Victor, Villeda, Saul A., and Walker, Tara L. (2023). Platelet-derived exerkine CXCL4/platelet factor 4 rejuvenates hippocampal neurogenesis and restores cognitive function in aged mice. Nature Communications 14 (1) 4375 1-20. https://doi.org/10.1038/s41467-023-39873-9
Erratum: Selenium mediates exercise-induced adult neurogenesis and reverses learning deficits induced by hippocampal injury and aging (Cell Metabolism (2022) 34(3) (408–423.e8), (S1550413122000055), (10.1016/j.cmet.2022.01.005))
Leiter, Odette, Zhuo, Zhan, Rust, Ruslan, Wasielewska, Joanna M., Grönnert, Lisa, Kowal, Susann, Overall, Rupert W., Adusumilli, Vijay S., Blackmore, Daniel G., Southon, Adam, Ganio, Katherine, McDevitt, Christopher A., Rund, Nicole, Brici, David, Mudiyan, Imesh Aththanayake, Sykes, Alexander M., Rünker, Annette E., Zocher, Sara, Ayton, Scott, Bush, Ashley I., Bartlett, Perry F., Hou, Sheng-Tao, Kempermann, Gerd, and Walker, Tara L. (2023). Erratum: Selenium mediates exercise-induced adult neurogenesis and reverses learning deficits induced by hippocampal injury and aging (Cell Metabolism (2022) 34(3) (408–423.e8), (S1550413122000055), (10.1016/j.cmet.2022.01.005)). Cell Metabolism 35 (6) 1085-1085. https://doi.org/10.1016/j.cmet.2023.04.019
Selenium supplementation provides potent neuroprotection following cerebral ischemia in mice
Zhuo, Zhan, Wang, Huimei, Zhang, Shuai, Bartlett, Perry F., Walker, Tara L., and Hou, Sheng-Tao (2023). Selenium supplementation provides potent neuroprotection following cerebral ischemia in mice. Journal of Cerebral Blood Flow and Metabolism 43 (7) 1060-1076. https://doi.org/10.1177/0271678x231156981
Protocol for three alternative paradigms to test spatial learning and memory in mice
Blackmore, Daniel G., Brici, David, and Walker, Tara L. (2022). Protocol for three alternative paradigms to test spatial learning and memory in mice. STAR Protocols 3 (3) 101500 1-16. https://doi.org/10.1016/j.xpro.2022.101500
The multifaceted role of platelets in mediating brain function
Burnouf, Thierry and Walker, Tara L. (2022). The multifaceted role of platelets in mediating brain function. Blood 140 (8) 815-827. https://doi.org/10.1182/blood.2022015970