Harnessing brain rhythms to restore and preserve function

Speaker: Dr Matilde Balbi
Queensland Brain Institute
University of Queensland
Harnessing brain rhythms to restore and preserve function
Abstract: Neural oscillations play a fundamental role in coordinating brain activity and supporting plasticity across the lifespan. In this talk, I will explore the therapeutic potential of non-invasive 40 Hz brain stimulation as a strategy to enhance brain health in both pathological and healthy ageing conditions. Drawing on evidence from preclinical and clinical studies, I will present findings from mouse models and human participants demonstrating how gamma-frequency stimulation can modulate neural activity, promote functional recovery after stroke, and mitigate age-related declines in brain function.
A particular focus will be placed on our multimodal research approach, which combines calcium imaging, electrophysiology, magnetic resonance imaging (MRI), electroencephalography (EEG), and behavioural assessments to examine the effects of 40 Hz stimulation across multiple scales of brain function. By integrating mechanistic insights from animal models with translational evidence from human studies, this work aims to advance our understanding of how rhythmic brain stimulation can be harnessed to promote recovery, resilience, and healthy ageing.
About Neuroscience Seminars
Neuroscience seminars at the QBI play a major role in the advancement of neuroscience in the Asia-Pacific region. The primary goal of these seminars is to promote excellence in neuroscience through the exchange of ideas, establishing new collaborations and augmenting partnerships already in place.
Seminars in the QBI Auditorium on Level 7 are held on Wednesdays at 12-1pm, which are sometimes simulcast on Zoom (with approval from the speaker). We also occassionally hold seminars from international speakers via Zoom. The days and times of these seminars will vary depending on the time zone of the speaker. Please see each seminar listed below for details.