Associate Professor Yanchuan Shi
Leader Neuroendocrinology Group
Garvan Institute of Medical Research
Faculty Member
Victor Chang Cardiac Research Institute 
Sydney


Uncovering the role of hypothalamic ARC NPY in salt-induced thermogenesis
 

Abstract: Obesity is a global epidemic and is a multifactorial disease associated with an increased risk of serious conditions, including type 2 diabetes, cardiovascular disease (CVD) and certain cancers. It arises from an imbalance between energy intake and energy expenditure. Gaining a deeper understanding of how energy balance is regulated under health and disease is essential for developing better therapeutics for obesity, diabetes and their comorbidities. While much research has focused on how sugar and fat disrupt energy homeostasis, the role of dietary salt, a common yet often overlooked dietary factor, remains poorly understood. In this talk, I will present our recent findings on how high salt intake modulates energy balance, with a particular focus on the critical involvement of the hypothalamic neuropeptide Y (NPY) system.

 

About Neuroscience Seminars

Neuroscience seminars at the QBI play a major role in the advancement of neuroscience in the Asia-Pacific region. The primary goal of these seminars is to promote excellence in neuroscience through the exchange of ideas, establishing new collaborations and augmenting partnerships already in place.

Seminars in the QBI Auditorium on Level 7 are held on Wednesdays at 12-1pm, which are sometimes simulcast on Zoom (with approval from the speaker). We also occassionally hold seminars from international speakers via Zoom. The days and times of these seminars will vary depending on the time zone of the speaker. Please see each seminar listed below for details. 

 

Neuroscience Seminars archive 2005-2018