Single molecule imaging of neuronal receptor interaction in health and disease
Speaker: Professor Laurent Groc
University of Bordeaux
CNRS, Interdisciplinary Institute for Neuroscience
France
Title: Single molecule imaging of neuronal receptor interaction in health and disease
Abstract: Brain cell comunication mainly occurs at the level of synapses in which neurotransmitters activate membrane receptors. Over the past decades, the development of superresolution microscopy and single molecule-based imaging have shed new and unsuspected ligths on the mechanisms underpinning neuronal communication in health and diseases. Here, I will describe how these approaches have revolutionized our understanding on how one of the key receptor in the brain, i.e. the NMDA glutamate receptor (NMDAR), tunes several aspects oft he synaptic transmission. I will further discuss how dysregulations of these new dimensions of the NMDAR-mediated signaling may directly contribute to major neurological and psychiatric disorders, paving the way for innovative therapeutical strategies.
About Neuroscience Seminars
Neuroscience seminars at the QBI play a major role in the advancement of neuroscience in the Asia-Pacific region. The primary goal of these seminars is to promote excellence in neuroscience through the exchange of ideas, establishing new collaborations and augmenting partnerships already in place.
Seminars in the QBI Auditorium on Level 7 are held on Wednesdays at 12-1pm, which are sometimes simulcast on Zoom (with approval from the speaker). We also occassionally hold seminars from international speakers via Zoom. The days and times of these seminars will vary depending on the time zone of the speaker. Please see each seminar listed below for details.
