Unveiling Nanoscale Secrets of Biological Systems Using Fluorescent Probes
Speaker: Dr Amandeep Kaur
ARC DECRA Fellow in the Faculty of Pharmacy and Pharmaceutical Science
Monash University
VIC
Title: Unveiling Nanoscale Secrets of Biological Systems Using Fluorescent Probes
Abstract: Understanding the biological world at the nanoscale is crucial for unravelling the complex mechanisms that govern life. At this level, the structure, identity, and environments of biomolecules play pivotal roles in cellular processes and functions. Technological advancements, including super-resolution microscopy, have emerged as powerful tools to address this need, offering researchers the ability to visualise and track specific molecules and structures with unprecedented precision. Consequently, fluorescent probes enabling nano-scale visualisation of biomolecules are highly sought after. This presentation will discuss three molecular imaging strategies we have developed: (i) fluorescent sensors for imaging the nanoscale structure of amyloids implicated in neurodegeneration, (ii) a molecular nose to discriminate between disease-associated and functional protein aggregates, and (iii) molecular rotors that report on biological environments. These innovative approaches promise to deepen our understanding of crucial biological processes at the molecular level.
About Neuroscience Seminars
Neuroscience seminars at the QBI play a major role in the advancement of neuroscience in the Asia-Pacific region. The primary goal of these seminars is to promote excellence in neuroscience through the exchange of ideas, establishing new collaborations and augmenting partnerships already in place.
Seminars in the QBI Auditorium on Level 7 are held on Wednesdays at 12-1pm, which are sometimes simulcast on Zoom (with approval from the speaker). We also occassionally hold seminars from international speakers via Zoom. The days and times of these seminars will vary depending on the time zone of the speaker. Please see each seminar listed below for details.
