Dr Ron Broide
Allergen Aesthetics - AbbVie

Title: Mechanisms & Pharmacology of Botulinum Neurotoxins

Botulinum neurotoxins (BoNT) are some of the most potent proteins known to man and at high doses, can cause symptoms of botulism. However, BoNTs have also proven to be valuable research tools and have been utilized for nearly 30 years to treat a growing number of medicinal indications, most recently, chronic migraine and overactive bladder. This presentation will begin by exploring the mechanism of action and pharmacology of BoNTs, particularly serotype A (BoNT/A). The second half of the presentation will describe the published results from two collaborative studies characterizing the effects of onabotulinumtoxinA (Botox) on cultured trigeminal sensory neurons, and in an animal model of headache induced by mild traumatic brain injury.

About Neuroscience Seminars

Neuroscience seminars at the QBI play a major role in the advancement of neuroscience in the Asia-Pacific region. The primary goal of these seminars is to promote excellence in neuroscience through the exchange of ideas, establishing new collaborations and augmenting partnerships already in place.

Seminars in the QBI Auditorium on Level 7 are held on Wednesdays at 12-1pm, which are sometimes simulcast on Zoom (with approval from the speaker). We also occassionally hold seminars from international speakers via Zoom. The days and times of these seminars will vary depending on the time zone of the speaker. Please see each seminar listed below for details. 


Neuroscience Seminars archive 2005-2018