Glymphatic Clearance in Cerebral Amyloid Angiopathy
A/Professor Susanne Van Veluw
Massachusetts General Hospital
Harvard Medical School
USA.
Title: Glymphatic Clearance in Cerebral Amyloid Angiopathy
Abstract: Cerebral amyloid angiopathy (CAA) is a common cerebral small vessel disease in the brains of older individuals. CAA is characterized by the accumulation of amyloid-beta in the walls of arterioles and leptomeningeal vessels and the leading cause of intracerebral hemorrhage. Impaired glymphatic clearance of amyloid-beta has been implicated in the early pathophysiology of the disease. Ongoing studies in the lab are focused on understanding the role of glymphatic clearance in CAA. Specifically, we use in vivo optical imaging in mouse models to zoom in on the driving forces of perivascular flow and human MRI to translate findings from the lab to the clinic.
About Neuroscience Seminars
Neuroscience seminars at the QBI play a major role in the advancement of neuroscience in the Asia-Pacific region. The primary goal of these seminars is to promote excellence in neuroscience through the exchange of ideas, establishing new collaborations and augmenting partnerships already in place.
Seminars in the QBI Auditorium are held on Wednesdays at 12-1pm, which are sometimes simulcast on Zoom (with approval from the speaker). We also occassionally hold seminars from international speakers via Zoom. The days and times of these seminars will vary depending on the time zone of the speaker. Please see each seminar listed below for details.
