Queensland Brain Institute

Lee Publications

Selected research articles

  • Chen HC, Spiers JG, Lerskiatiphanich T, Parker SE, Lavidis NA, Fung JN, Woodruff TM, Lee JD. (2024). Complement C5a receptor signaling alters stress responsiveness and modulates microglia following chronic stress exposure. Biological Psychiatry: Global Open Science. doi: 10.1016/j.bpsgos.2024.100306

  • McDonald TS, Kumar V, Fung JN, Woodruff TM, Lee JD. (2021). Glucose clearance and uptake is increased in the SOD1G93A mouse model of amyotrophic lateral sclerosis through an insulin‐independent mechanism. The FASEB Journal, 35 (7) e21707, e21707. doi: 10.1096/fj.202002450r
  • Lee JD, Heshmat S, Heggie S, Thorpe KA, McCombe PA, Henderson RD. (2021). Clinical and electrophysiological examination of pinch strength in patients with amyotrophic lateral sclerosis. Muscle and Nerve, 63 (1) mus.27111, 108-113. doi: 10.1002/mus.27111
  • Lee JD, McDonald TS, Fung JN, Woodruff TM. (2020). Absence of Receptor for Advanced Glycation End Product (RAGE) Reduces Inflammation and Extends Survival in the hSOD1 Mouse Model of Amyotrophic Lateral Sclerosis. Molecular Neurobiology, 57 (10), 4143-4155. doi: 10.1007/s12035-020-02019-9
  • Deora V, Lee JD, Albornoz EA, McAlary L, Jagaraj CJ, Robertson AAB, Atkin JD, Cooper MA, Schroder K, Yerbury JJ, Gordon R, Woodruff TM. (2020). The microglial NLRP3 inflammasome is activated by amyotrophic lateral sclerosis proteins. Glia, 68 (2) glia.23728, 407-421. doi: 10.1002/glia.23728
  • Lee JD, Levin SC, Willis EF, Li R, Woodruff TM, Noakes PG. (2018). Complement components are upregulated and correlate with disease progression in the TDP-43 mouse model of amyotrophic lateral sclerosis. Journal of Neuroinflammation, 15 (1) 171, 171. doi: 10.1186/s12974-018-1217-2
  • Lee JD, Kumar V, Fung JN, Ruitenberg MJ, Noakes PG, Woodruff TM. (2017). Pharmacological inhibition of complement C5a-C5a1 receptor signalling ameliorates disease pathology in the hSOD1G93A mouse model of amyotrophic lateral sclerosis. British Journal of Pharmacology, 173 (8), 689-699. doi: 10.1111/bph.13730
  • Spiers JG, Chen HC, Steyn FJ, Lavidis NA, Woodruff TM, Lee JD. (2017). Non-invasive assessment of altered activity following restraint in mice using an automated physiological monitoring system. Stress, 20 (1), 59-67. doi: 10.1080/10253890.2016.1276898
  • Woodruff TM, Lee JD, Noakes PG. (2014). Role for terminal complement activation in amyotrophic lateral sclerosis disease progression. Proceeding of the National Academy of Sciences of the United States of America, 111 (1), E3-E4. doi: 10.1073/pnas.1321248111
  • Lee JD, Kamaruzaman NA, Fung JN, Taylor SM, Turner BJ, Atkin JD, Woodruff TM, Noakes PG. (2013). Dysregulation of the complement cascade in the hSOD1(G93A) transgenic mouse model of amyotrophic lateral sclerosis. Journal of Neuroinflammation, 10 (1) 119, 119. doi: 10.1186/1742-2094-10-119

 

Selected reviews

  • McDonald TS, Lerskiatiphanich T, Woodruff TM, McCombe PA, Lee JD. (2022). Potential mechanisms to modify impaired glucose metabolism in neurodegenerative disorders. Journal of Cerebral Blood Flow and Metabolism, 43 (1), 26-43. doi: 10.1177/0271678x221135061
  • McDonald TS, McCombe PA, Woodruff, TM, Lee JD. (2020). The potential interplay between energy metabolism and innate complement activation in amyotrophic lateral sclerosis. The FASEB Journal, 34 (6) fj.201901781, 7225-7233. doi: 10.1096/fj.201901781
  • Parker SE, Hanton AM, Stefanou SN, Noakes PG, Woodruff TM, Lee JD. (2019). Revisiting the role of the innate immune complement system in ALS. Neurobiology of Disease, 127, 223-232. doi: 10.1016/j.nbd.2019.03.003