van Swinderen publications

Presynaptic neurotransmission: a bottleneck to recovery from general anesthesia?

van Zundert, André A. J., Cylinder, Drew M., and van Swinderen, Bruno (2025). Presynaptic neurotransmission: a bottleneck to recovery from general anesthesia?. Anesthesia and Analgesia 142 (1) 07695 56-63. https://doi.org/10.1213/ane.0000000000007695

Wakefulness can be distinguished from general anesthesia and sleep in flies using a massive library of univariate time series analyses

Leung, Angus, Mahmoud, Ahmed, Jeans, Travis, Fulcher, Ben D., van Swinderen, Bruno, and Tsuchiya, Naotsugu (2025). Wakefulness can be distinguished from general anesthesia and sleep in flies using a massive library of univariate time series analyses. PLoS Biology 23 (7 July) e3003217 1-32. https://doi.org/10.1371/journal.pbio.3003217

Long-term multichannel recordings in Drosophila flies reveal altered predictive processing during sleep compared to wake

Van De Poll, Matthew N. and van Swinderen, Bruno (2025). Long-term multichannel recordings in Drosophila flies reveal altered predictive processing during sleep compared to wake. Journal of Experimental Biology 228 (11) jeb250165 1-12. https://doi.org/10.1242/jeb.250165

A basic role for glia in sleep homeostasis

Kirszenblat, Leonie and van Swinderen, Bruno (2025). A basic role for glia in sleep homeostasis. Nature Neuroscience 28 (6) 1118-1120. https://doi.org/10.1038/s41593-025-01963-w

Alcohol use: Passing out has long-term effects on sleep

van Swinderen, Bruno (2025). Alcohol use: Passing out has long-term effects on sleep. Current Biology 35 (5) R191-R193. https://doi.org/10.1016/j.cub.2025.01.051

Whole-brain calcium imaging in Drosophila during sleep and wake

Tainton-Heap, Lucy, Troup, Michael, Van De Poll, Matthew, and van Swinderen, Bruno (2024). Whole-brain calcium imaging in Drosophila during sleep and wake. Cold Spring Harbor Protocols 2024 (9) top108394 pdb.top108394. https://doi.org/10.1101/pdb.prot108419

Whole-brain electrophysiology in Drosophila during sleep and wake

Van De Poll, Matthew and van Swinderen, Bruno (2024). Whole-brain electrophysiology in Drosophila during sleep and wake. Cold Spring Harbor Protocols 2024 (9) 1-2. https://doi.org/10.1101/pdb.prot108418

Synapse-specific trapping of SNARE machinery proteins in the anesthetized Drosophila brain

Hines, Adam D., Kewin, Amber B., Van De Poll, Matthew N., Anggono, Victor, Bademosi, Adekunle T., and van Swinderen, Bruno (2024). Synapse-specific trapping of SNARE machinery proteins in the anesthetized Drosophila brain. The Journal of Neuroscience 44 (24) e0588232024 1-18. https://doi.org/10.1523/jneurosci.0588-23.2024

Time to wake up! The ongoing search for general anesthetic reversal agents

Cylinder, Drew M., van Zundert, André A. J., Solt, Ken, and van Swinderen, Bruno (2024). Time to wake up! The ongoing search for general anesthetic reversal agents. Anesthesiology 140 (3) 610-627. https://doi.org/10.1097/aln.0000000000004846

Multivariate classification of multichannel long-term electrophysiology data identifies different sleep stages in fruit flies

Jagannathan, Sridhar R., Jeans, Travis, Van De Poll, Matthew N., and van Swinderen, Bruno (2024). Multivariate classification of multichannel long-term electrophysiology data identifies different sleep stages in fruit flies. Science Advances 10 (8) eadj4399 eadj4399. https://doi.org/10.1126/sciadv.adj4399

Experimentally induced active and quiet sleep engage non-overlapping transcriptional programs in Drosophila

Anthoney, Niki, Tainton-Heap, Lucy, Luong, Hang, Notaras, Eleni, Kewin, Amber B., Zhao, Qiongyi, Perry, Trent, Batterham, Philip, Shaw, Paul J., and van Swinderen, Bruno (2023). Experimentally induced active and quiet sleep engage non-overlapping transcriptional programs in Drosophila. eLife 12 RP88198 . https://doi.org/10.7554/elife.88198

Neural ensemble fragmentation in the anesthetized Drosophila brain

Troup, Michael, Tainton-Heap, Lucy A L, and van Swinderen, Bruno (2023). Neural ensemble fragmentation in the anesthetized Drosophila brain. The Journal of Neuroscience 43 (14) 2537-2551. https://doi.org/10.1523/jneurosci.1657-22.2023

Experimentally induced active and quiet sleep engage non-overlapping transcriptomes in Drosophila

Anthoney, Niki, Tainton-Heap, Lucy A. L., Luong, Hang, Notaras, Eleni, Zhao, Qiongyi, Perry, Trent, Batterham, Philip, Shaw, Paul J., and van Swinderen, Bruno (2023). Experimentally induced active and quiet sleep engage non-overlapping transcriptomes in Drosophila. eLife 12 . https://doi.org/10.7554/eLife.88198.1

Sleep-promoting neurons remodel their response properties to calibrate sleep drive with environmental demands

Dissel, Stephane, Klose, Markus K., van Swinderen, Bruno, Cao, Lijuan, Ford, Melanie, Periandri, Erica M., Jones, Joseph D., Li, Zhaoyi, and Shaw, Paul J. (2022). Sleep-promoting neurons remodel their response properties to calibrate sleep drive with environmental demands. PLoS Biology 20 (9) e3001797 1-25. https://doi.org/10.1371/journal.pbio.3001797