Professor Jürgen Götz: Basic neuroscience and Alzheimer's research

The Götz group is a multidisciplinary, international laboratory with its members being trained in biology or engineering. We use standard cellular, molecular, histological, biochemical and behavioural methods. Other techniques include click chemistry, SWATH proteomics and super resolution microscopy. We further generate our own transgenic mouse models including CRISPR gene-edited mice. The team combine approaches which makes the Götz laboratory an exciting place to work and research. As low frequency ultrasound is still a research area in its infancy, there is a lot for us to discover.

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Researcher biography

Professor Jürgen Götz is Foundation Chair of Dementia Research and Director of the Clem Jones Centre for Ageing Dementia Research at the Queensland Brain Institute (University of Queensland).

He completed undergraduate studies at the Biocenter of the University of Basel, before joining the laboratory of Nobel Laureate Georges Köhler to obtain his PhD degree in immunology. He then took up postdoctoral positions at UCSF (San Francisco) and Sandoz Ltd (now Novartis, Basel), and worked as Research Group Leader at the University of Zurich (Switzerland). Before taking up his current position, he was a Professor and Chair of Molecular Biology at the University of Sydney.

Professor Götz is an internationally renowned expert in fundamental research in Alzheimer’s disease (AD), focusing on the cellular and molecular mechanisms of how tau and Aβ cause neurodegeneration. Recently, he developed a non-pharmacological ultrasound-based treatment strategy that removes toxic Aβ and tau in mice and restores memory functions, presenting ultrasound as a novel treatment modality for diseases of the brain.