Professor Stephen Williams: Synaptic integration in neural networks

Our aim is to understand how information is processed and computed by neuronal circuits, and relate this to the control of behaviour. We primarily study neuronal circuit operations in the neocortex and retina using state-of-the-art multi-site electrophysiological and optical recording techniques. We have discovered that active dendritic integration in the output neurons of the retina and neocortex underlies behaviourally engaged circuit-level computations. Our ongoing work at the single cell level determines how regenerative activity is generated in and spreads throughout the complex dendritic tree of neurons to control action potential output and, at the network level, the neuromodulatory control of neuronal circuit operations.

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Researcher biography

Professor Stephen Williams joined the Queensland Brain Institute in 2010 to establish a laboratory studying synaptic integration in neuronal networks. He moved to QBI from the MRC Laboratory of Molecular Biology, Cambridge, UK where he was a tenured programme leader.