Dr Renata Nedel Pertile
Postdoctoral Research Fellow
Queensland Brain Institute
+61 7 334 66362
Researcher biography
Renata received her PhD in Biomedical Engineering from University of Minho, Portugal, in 2010. Prior to this, she completed her Bachelor degree in Biological Sciences in Brazil (2004) and Master's degree in Chemical Engineering from Federal University of Santa Catarina - UFSC, Brazil (2007). Renata has over 10 years of experience in using techniques like Animal Cell Culture, Molecular Biology and Tissue Engineering/Biomaterials to conduct experiments in various research fields. More recently, she spent one year working on Animal Behaviour and Genetics at the Cell Biology and Development Department at Federal University of Santa Catarina, studying animal models of anxiety. Since 2014, Renata works at the Queensland Brain Institute in Brisbane, researching the impact of vitamin D deficiency on brain development and the ontogeny of dopaminergic neurons.
Book Chapter
Andrade, Fabia Karine, Pertile, Renata Ap. Nedel, Dourado, Fernando and Gama, Francisco M. (2010). Bacterial cellulose: properties, production and applications. Cellulose: structure and properties, derivatives and industrial uses. (pp. 427-458) New York, New York, USA: Nova Science Publishers.
Journal Articles
Pertile, Renata Aparecida Nedel, Brigden, Rachel, Raman, Vanshika, Cui, Xiaoying, Du, Zilong and Eyles, Darryl (2023). Vitamin D: A potent regulator of dopaminergic neuron differentiation and function. Journal of Neurochemistry. doi: 10.1111/jnc.15829
Aparecida Nedel Pertile, Renata, Kiltschewskij, Dylan, Geaghan, Michael, Barnett, Michelle, Cui, Xiaoying, Cairns, Murray J. and Eyles, Darryl (2022). Developmental vitamin D-deficiency increases the expression of microRNAs involved in dopamine neuron development. Brain Research, 1789 147953, 147953. doi: 10.1016/j.brainres.2022.147953
Brandon, Anastasia, Cui, Xiaoying, Luan, Wei, Ali, Asad Amanat, Pertile, Renata Aparecida Nedel, Alexander, Suzanne Adele and Eyles, Darryl Walter (2022). Prenatal hypoxia alters the early ontogeny of dopamine neurons. Translational Psychiatry, 12 (1) 238, 238. doi: 10.1038/s41398-022-02005-w
Cui, Xiaoying, Pertile, Renata Ap. Nedel, Du, Zilong, Wei, Wei, Sun, Zichun, Eyles, Darryl W. and Kesby, James P. (2021). Developmental inhibition of long intergenic non-coding RNA, HOTAIRM1, impairs dopamine neuron differentiation and maturation. International Journal of Molecular Sciences, 22 (14) 7268, 7268. doi: 10.3390/ijms22147268
Ali, Asad Amanat, Cui, Xiaoying, Pertile, Renata Aparecida Nedel, Li, Xiang, Medley, Gregory, Alexander, Suzanne Adele, Whitehouse, Andrew J. O., McGrath, John J. and Eyles, Darryl Walter (2020). Developmental vitamin D deficiency increases foetal exposure to testosterone. Molecular Autisum, 11 (1) 96, 96. doi: 10.1186/s13229-020-00399-2
Pertile, Renata A. N., Cui, Xiaoying, Hammond, Luke and Eyles, Darryl W. (2018). Vitamin D regulation of GDNF/Ret signaling in dopaminergic neurons. The FASEB Journal, 32 (2), fj201700713R-828. doi: 10.1096/fj.201700713R
Cui, Xiaoying, Pertile, Renata and Eyles, Darryl W. (2017). The vitamin D receptor (VDR) binds to the nuclear matrix via its hinge domain: a potential mechanism for the reduction in VDR mediated transcription in mitotic cells. Molecular and Cellular Endocrinology, 472, 18-25. doi: 10.1016/j.mce.2017.11.015
Mazur, F. G., Oliveira, L. F. G., Cunha, M. P., Rodrigues, A. L. S., Pértile, R. A. N., Vendruscolo, L. F. and Izídio, G. S. (2017). Effects of physical exercise and social isolation on anxiety-related behaviors in two inbred rat strains. Behavioural Processes, 142, 70-78. doi: 10.1016/j.beproc.2017.06.001
Pertile, R. A. N., Corvino, M. E. , Marchette, R. C. N. , Pavesi, E. , Cavalli, J. , Ramos, A. and Izídio, G. S. (2017). The quinpirole hypolocomotive effects are strain and route of administration dependent in SHR and SLA16 isogenic rats. Behavior Genetics, 47 (5), 552-563. doi: 10.1007/s10519-017-9865-z
Pertile, Renata A. N., Cui, Xiaoying and Eyles, Darryl W. (2016). Vitamin D signaling and the differentiation of developing dopamine systems. Neuroscience, 333, 193-203. doi: 10.1016/j.neuroscience.2016.07.020
Mack, Josiel Mileno, Schamne, Marissa Giovanna, Sampaio, Tuane Bazanella, Pertile, Renata Aparecida Nedel, Carlos Magno Fernandes, Pedro Augusto, Markus, Regina P. and Prediger, Rui Daniel (2016). Melatoninergic system in Parkinson's disease: from neuroprotection to the management of motor and nonmotor symptoms. Oxidative Medicine and Cellular Longevity, 2016 3472032, 3472032-31. doi: 10.1155/2016/3472032
Cui, X., Pertile, R., Liu, P. and Eyles, D. W. (2015). Vitamin D regulates tyrosine hydroxylase expression: N-cadherin a possible mediator. Neuroscience, 304, 90-100. doi: 10.1016/j.neuroscience.2015.07.048
Jozala, Angela Faustino, Nedel Pertile, Renata Aparecida, dos Santos, Carolina Alves, Santos-Ebinuma, Valeria de Carvalho, Seckler, Marcelo Martins, Gama, Francisco Miguel and Pessoa, Adalberto, Jr. (2015). Bacterial cellulose production by Gluconacetobacter xylinus by employing alternative culture media. Applied Microbiology and Biotechnology, 99 (3), 1181-1190. doi: 10.1007/s00253-014-6232-3
Stumpf, Taisa R., Pertile, Renata A. N., Rambo, Carlos R. and Porto, Luismar M. (2013). Enriched glucose and dextrin mannitol-based media modulates fibroblast behavior on bacterial cellulose membranes. Materials Science and Engineering C, 33 (8), 4739-4745. doi: 10.1016/j.msec.2013.07.035
Pertile, Renata, Moreira, Susana, Andrade, Fabia, Domingues, Lucilia and Gama, Miguel (2012). Bacterial cellulose modified using recombinant proteins to improve neuronal and mesenchymal cell adhesion. Biotechnology Progress, 28 (2), 526-532. doi: 10.1002/btpr.1501
Pertile, Renata A. N., Moreira, Susana, Gil da Costa, Rui M., Correia, Alexandra, Guardao, Luisa, Gartner, Fatima, Vilanova, Manuel and Gama, Miguel (2012). Bacterial cellulose: long-term biocompatibility studies. Journal of Biomaterials Science, Polymer Edition, 23 (10), 1339-1354. doi: 10.1163/092050611X581516
Pertile, Renata A. N., Andrade, Fabia K., Alves, Clodomiro, Jr. and Gama, Miguel (2010). Surface modification of bacterial cellulose by nitrogen-containing plasma for improved interaction with cells. Carbohydrate Polymers, 82 (3), 692-698. doi: 10.1016/j.carbpol.2010.05.037
Conference Paper
Cui, X., Pertile, R. and Eyles, D. (2015). The association of the vitamin D receptor and nuclear matrix in a neuroblastoma line. 25th Biennial Meeting of the International Society for Neurochemistry jointly with the 13th Meeting of the Asian-Pacific Society for Neurochemistry in conjunction with the 35th Meeting of the Australasian Neuroscience Society, Cairns, QLD, Australia, 23-27 August 2015. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/jnc.13189