Computational cognitive neuroscience

About

Our research is theoretically driven by ideas of Predictive Coding, a computational framework that posits the brain is a predictive, efficient and adaptive machine. The main goal of the group is to understand how the brain’s circuitry implements these mechanisms, which enable us to make predictions about future events as well as learn about, and adapt to, the contingencies of a novel environment.

Along with our work on typical cognition in healthy human individuals, our mission is to contribute to the understanding of mental illness, in particular to those conditions where predictive processes and brain circuitry are disrupted such as in schizophrenia and anxiety.  To pursue this endeavour we use a combination of computational modelling, machine learning and brain imaging techniques such as magnetoencephalography (MEG), electroencephalography (EEG), and magnetic resonance imaging (MRI).

Contact

  +61 7 344 32435

  m.garrido@uq.edu.au

  Garrido lab website (CJCADR)

Group Publications

Research Areas

  • Predictive Coding 
  • Schizophrenia
  • Anxiety 
  • MEG, EEG, and MRI techniques 
  • Computational modelling
  • Machine learning

Group Leader

  • Dr Marta Garrido

    Affiliated Research Fellow
    Centre for Advanced Imaging
    UQ Fellow
    Queensland Brain Institute
    Affiliated Senior Lecturer
    School of Mathematics and Physics

Research Members


Students


Support Staff

  • Ms Roxanne Jemison

    Node Administrator
    Queensland Brain Institute
    Administrative Officer
    School of Mathematics and Physics

Prediction of speech sounds is facilitated by a functional fronto-temporal network
Oestreich, Lena K. L., Whitford, Thomas J. and Garrido, Marta (2018) Prediction of speech sounds is facilitated by a functional fronto-temporal network. Frontiers in Neural Circuits12 43. doi:10.3389/fncir.2018.00043

Altered auditory processing and effective connectivity in 22q11.2 deletion syndrome
Larsen, Kit Melissa, Mørup, Morten, Birknow, Michelle Rosgaard, Fischer, Elvira, Hulme, Oliver, Vangkilde, Anders, Schmock, Henriette, Baaré, William Frans Christiaan, Didriksen, Michael, Olsen, Line, Werge, Thomas, Siebner, Hartwig R. and Garrido, Marta I. (2018) Altered auditory processing and effective connectivity in 22q11.2 deletion syndrome. Schizophrenia Research197 328-336. doi:10.1016/j.schres.2018.01.026

Bayesian mapping reveals that attention boosts neural responses to predicted and unpredicted stimuli
Garrido, Marta I., Rowe, Elise G., Halasz, Veronika and Mattingley, Jason B. (2017) Bayesian mapping reveals that attention boosts neural responses to predicted and unpredicted stimuli. Cerebral Cortex, . doi:10.1093/cercor/bhx087

Sensory prediction errors in the continuum of psychosis
Randeniya, R., Oestreich, L. K. L. and Garrido, M. I. (2017) Sensory prediction errors in the continuum of psychosis.Schizophrenia Research, . doi:10.1016/j.schres.2017.04.019

The un-predictive brain under threat: a neuro-computational account of anxious hypervigilance
Cornwell, Brian R., Garrido, Marta I., Overstreet, Cassie, Pine, Daniel S. and Grillon, Christian (2017) The un-predictive brain under threat: a neuro-computational account of anxious hypervigilance. Biological Psychiatry82 6: 447-454. doi:10.1016/j.biopsych.2017.06.031

Auditory prediction errors as individual biomarkers of schizophrenia
Taylor, J. A., Matthews, N., Michie, P. T., Rosa, M. J. and Garrido, M. I. (2017) Auditory prediction errors as individual biomarkers of schizophrenia. NeuroImage: Clinical15 264-273. doi:10.1016/j.nicl.2017.04.027

A rapid subcortical amygdala route for faces irrespective of spatial frequency and emotion
McFadyen, Jessica, Mermillod, Martial, Mattingley, Jason B., Halasz, Veronika and Garrido, Marta I. (2017) A rapid subcortical amygdala route for faces irrespective of spatial frequency and emotion. Journal of Neuroscience37 14: 3864-3874. doi:10.1523/JNEUROSCI.3525-16.2017

Timing in predictive coding: the roles of task relevance and global probability
Sherwell, Chase S., Garrido, Marta I. and Cunnington, Ross (2017) Timing in predictive coding: the roles of task relevance and global probability. Journal of Cognitive Neuroscience29 5: 780-792. doi:10.1162/jocn_a_01085

Surprise responses in the human brain demonstrate statistical learning under high concurrent cognitive demand
Garrido, Marta Isabel, Teng, Chee Leong James, Taylor, Jeremy Alexander, Rowe, Elise Genevieve and Mattingley, Jason Brett (2016) Surprise responses in the human brain demonstrate statistical learning under high concurrent cognitive demand. n p j Science of Learning1 . doi:10.1038/npjscilearn.2016.6

Empirical Bayes for group (DCM) studies: a reproducibility study
Litvak, Vladimir, Garrido, Marta, Zeidman, Peter and Friston, Karl (2015) Empirical Bayes for group (DCM) studies: a reproducibility study. Frontiers in Human Neuroscience9 DEC: 670.1-670.12. doi:10.3389/fnhum.2015.00670

Ventromedial prefrontal cortex drives hippocampal theta oscillations induced by mismatch computations
Garrido, Marta I., Barnes, Gareth R., Kumaran, Dharshan, Maguire, Eleanor A. and Dolan, Raymond J. (2015) Ventromedial prefrontal cortex drives hippocampal theta oscillations induced by mismatch computations.NeuroImage120 362-370. doi:10.1016/j.neuroimage.2015.07.016

The maturation of mismatch negativity networks in normal adolescence
Cooray, G. K., Garrido, M. I., Brismar, T. and Hyllienmark, L. (2016) The maturation of mismatch negativity networks in normal adolescence. Clinical Neurophysiology127 1: 520-529. doi:10.1016/j.clinph.2015.06.026

Time-varying effective connectivity during visual object naming as a function of semantic demands
Poch, Claudia, Garrido, Marta I, Igoa, Jose Manuel, Belinchon, Mercedes, Garcia-Morales, Irene and Campo, Pablo (2015) Time-varying effective connectivity during visual object naming as a function of semantic demands. Journal of Neuroscience35 23: 8768-8776. doi:10.1523/JNEUROSCI.4888-14.2015

Development of effective connectivity in the core network for face perception
He, Wei, Garrido, Marta I., Sowman, Paul F., Brock, Jon and Johnson, Blake W. (2015) Development of effective connectivity in the core network for face perception. Human Brain Mapping36 6: 2161-2173. doi:10.1002/hbm.22762

Sensory deviancy detection measured directly within the human nucleus accumbens
Dürschmid, Stefan, Zaehle, Tino, Hinrichs, Hermann, Heinze, Hans-Jochen, Voges, Jürgen, Garrido, Marta I., Dolan, Raymond J. and Knight, Robert T. (2015) Sensory deviancy detection measured directly within the human nucleus accumbens. Cerebral Cortex26 3: 1168-1175. doi:10.1093/cercor/bhu304

Sparse network-based models for patient classification using fMRI
Rosa, Maria J., Portugal, Liana, Hahn, Tim, Fallgatter, Andreas J., Garrido, Marta I., Shawe-Taylor, John and Mourao-Miranda, Janaina (2015) Sparse network-based models for patient classification using fMRI. NeuroImage105 493-506. doi:10.1016/j.neuroimage.2014.11.021

Subcortical amygdala pathways enable rapid face processing
Garvert, Mona M., Friston, Karl J., Dolan, Raymond J. and Garrido, Marta I. (2014) Subcortical amygdala pathways enable rapid face processing. NeuroImage102 P2: 309-316. doi:10.1016/j.neuroimage.2014.07.047

Effective connectivity reveals right-hemisphere dominance in audiospatial perception: implications for models of spatial neglect
Dietz, Martin J., Friston, Karl J., Mattingley, Jason B., Roepstorff, Andreas and Garrido, Marta I. (2014) Effective connectivity reveals right-hemisphere dominance in audiospatial perception: implications for models of spatial neglect. Journal of Neuroscience34 14: 5003-5011. doi:10.1523/JNEUROSCI.3765-13.2014

A mechanistic model of mismatch negativity in the ageing brain
Cooray, Gerald, Garrido, Marta I., Hyllienmark, L. and Brismar, Tom (2014) A mechanistic model of mismatch negativity in the ageing brain. Clinical Neurophysiology125 9: 1774-1782. doi:10.1016/j.clinph.2014.01.015

A Neurocomputational Model of the Mismatch Negativity
Lieder, Falk, Stephan, Klaas E., Daunizeau, Jean, Garrido, Marta I. and Friston, Karl J. (2013) A Neurocomputational Model of the Mismatch Negativity. PLoS Computational Biology9 11: e1003288.1-e1003288.14. doi:10.1371/journal.pcbi.1003288

Network configuration and working memory impairment in mesial temporal lobe epilepsy
Campo, Pablo, Garrido, Marta I., Moran, Rosalyn J., Garcia-Morales, Irene, Poch, Claudia, Toledano, Rafael, Gil-Nagel, Antonio, Dolan, Raymond J. and Friston, Karl J. (2013) Network configuration and working memory impairment in mesial temporal lobe epilepsy. NeuroImage72 48-54. doi:10.1016/j.neuroimage.2013.01.036

Outlier responses reflect sensitivity to statistical structure in the human brain
Garrido, Marta I., Sahani, Maneesh and Dolan, Raymond J. (2013) Outlier responses reflect sensitivity to statistical structure in the human brain. PLoS Computational Biology9 3: e1002999.1-e1002999.10. doi:10.1371/journal.pcbi.1002999

Modelling trial-by-trial changes in the mismatch negativity
Lieder, Falk, Daunizeau, Jean, Garrido, Marta I., Friston, Karl J. and Stephan, Klaas E. (2013) Modelling trial-by-trial changes in the mismatch negativity. PLoS Computational Biology9 2: e1002911.1-e1002911.16. doi:10.1371/journal.pcbi.1002911

Brain connectivity in disorders of consciousness
M. Boly, M. Massimini, M.I. Garrido, O. Gosseries, Q. Noirhomme, S. Laureys, A. Soddu (2012). Brain connectivity in disorders of consciousness. Brain Connectivity 2:1-10.

Brain connectivity: The feel of blindsight
Garrido, Marta I. (2012) Brain connectivity: The feel of blindsight. Current Biology22 15: R599-R600. doi:10.1016/j.cub.2012.06.012

Dynamic Causal Modelling of epileptic seizure propagation pathways: A combined EEG-fMRI study
Murta, Teresa, Leal, Alberto, Garrido, Marta I. and Figueiredo, Patricia (2012) Dynamic Causal Modelling of epileptic seizure propagation pathways: A combined EEG-fMRI study. Neuroimage62 3: 1634-1642. doi:10.1016/j.neuroimage.2012.05.053

Functional Evidence for a Dual Route to Amygdala
Garrido, Marta I., Barnes, Gareth R., Sahani, Maneesh and Dolan, Raymond J. (2012) Functional Evidence for a Dual Route to Amygdala. Current Biology22 2: 129-134. doi:10.1016/j.cub.2011.11.056

Remote Effects of Hippocampal Sclerosis on Effective Connectivity during Working Memory Encoding: A Case of Connectional Diaschisis?
Campo, Pablo, Garrido, Marta I., Moran, Rosalyn J., Maestu, Fernando, Garcia-Morales, Irene, Gil-Nagel, Antonio, del Pozo, Francisco, Dolan, Raymond J. and Friston, Karl J. (2012) Remote Effects of Hippocampal Sclerosis on Effective Connectivity during Working Memory Encoding: A Case of Connectional Diaschisis?. Cerebral Cortex22 6: 1225-1236. doi:10.1093/cercor/bhr201

Surprise leads to noisier perceptual decisions
Garrido, Marta I., Dolan, Raymond J. and Sahani, Maneesh (2011) Surprise leads to noisier perceptual decisions. i-Perception2 2: 112-120. doi:10.1068/i0411

Preserved Feedforward But Impaired Top-Down Processes in the Vegetative State
Boly, Melanie, Garrido, Marta Isabel, Gosseries, Olivia, Bruno, Marie-Aurelie, Boveroux, Pierre, Schnakers, Caroline, Massimini, Marcello, Litvak, Vladimir, Laureys, Steven and Friston, Karl (2011) Preserved Feedforward But Impaired Top-Down Processes in the Vegetative State. Science332 6031: 858-862. doi:10.1126/science.1202043

Response to Comment on "Preserved Feedforward But Impaired Top-Down Processes in the Vegetative State"
Boly, Melanie, Garrido, Marta Isabel, Gosseries, Olivia, Bruno, Marie-Aurelie, Boveroux, Pierre, Schnakers, Caroline, Massimini, Marcello, Litvak, Vladimir, Laureys, Steven and Friston, Karl (2011) Response to Comment on "Preserved Feedforward But Impaired Top-Down Processes in the Vegetative State". Science334 6060: . doi:10.1126/science.1210240

Repetition suppression and plasticity in the human brain
Garrido, Marta I., Kilner, James M., Kiebel, Stefan J., Stephan, Klaas E., Baldeweg, Torsten and Friston, Karl J. (2009) Repetition suppression and plasticity in the human brain. Neuroimage48 1: 269-279. doi:10.1016/j.neuroimage.2009.06.034

Dynamic causal modeling for EEG and MEG
Kiebel, Stefan J., Garrido, Marta I., Moran, Rosalyn, Chen, Chun-Chuan and Friston, Karl J. (2009) Dynamic causal modeling for EEG and MEG. Human Brain Mapping30 6: 1866-1876. doi:10.1002/hbm.20775

Dynamic Causal Modeling of the Response to Frequency Deviants
Garrido, Marta I., Kilner, James M., Kiebel, Stefan J. and Friston, Karl J. (2009) Dynamic Causal Modeling of the Response to Frequency Deviants. Journal of Neurophysiology101 5: 2620-2631. doi:10.1152/jn.90291.2008

The mismatch negativity: a review of underlying mechanisms
Garrido, Marta I., Kilner, James M., Stephan, Klaas E. and Friston, Karl J. (2009) The mismatch negativity: a review of underlying mechanisms. Clinical Neurophysiology120 3: 453-463. doi:10.1016/j.clinph.2008.11.029

The functional anatomy of the MMN: A DCM study of the roving paradigm
Garrido, Marta I., Friston, Karl J., Kiebel, Stefan J., Stephan, Klaas E., Baldeweg, Torsten and Kilner, James M. (2008) The functional anatomy of the MMN: A DCM study of the roving paradigm. Neuroimage42 2: 936-944. doi:10.1016/j.neuroimage.2008.05.018

Dynamic causal modelling for EEG and MEG
Kiebel, Stefan J., Garrido, Marta I., Moran, Rosalyn J. and Friston, Karl J. (2008) Dynamic causal modelling for EEG and MEG. Cognitive Neurodynamics2 2: 121-136. doi:10.1007/s11571-008-9038-0

Evoked brain responses are generated by feedback loops
Garrido, Marta I., Kilner, James M., Kiebel, Stefan J. and Friston, Karl J. (2007) Evoked brain responses are generated by feedback loops. Proceedings of the National Academy of Sciences of the United States of America104 52: 20961-20966. doi:10.1073/pnas.0706274105

Dynamic causal modelling of evoked potentials: A reproducibility study
Garrido, Marta I., Kilner, James M., Kiebel, Stefan J., Stephan, Klaas E. and Friston, Karl J. (2007) Dynamic causal modelling of evoked potentials: A reproducibility study. Neuroimage36 3: 571-580. doi:10.1016/j.neuroimage.2007.03.014

Dynamic causal modelling of evoked responses: The role of intrinsic connections
Kiebel, Stefan J., Garrido, Marta I. and Friston, Karl J. (2007) Dynamic causal modelling of evoked responses: The role of intrinsic connections. Neuroimage36 2: 332-345. doi:10.1016/j.neuroimage.2007.02.046


  • Professor Karl Friston, University College London
  • Professor Ray Dolan, University College London
  • Professor Klaas Stephan, University of Zurich
  • Professor Michael Breakspear, Queensland Institute for Medical Research
  • Professor Pat Michie, The University of Newcastle
  • Associate Professor Naotsugo Tsuchiya, Monash University

 

Senior research leader Dr Marta Garrido is trying to understand how the brain works in people with schizophrenia, so better diagnoses can be developed.

She aims to understand how the brain's circuitry is predictive and adaptive - i.e. how the brain makes predictions about future events as well as learning about, and adapting (or not) to , a new environment.