Computational cognitive neuroscience


Our research is theoretically driven by ideas of Predictive Coding, a computational framework that posits the brain is a predictive, efficient and adaptive machine. The main goal of the group is to understand how the brain’s circuitry implements these mechanisms, which enable us to make predictions about future events as well as learn about, and adapt to, the contingencies of a novel environment.

Along with our work on typical cognition in healthy human individuals, our mission is to contribute to the understanding of mental illness, in particular to those conditions where predictive processes and brain circuitry are disrupted such as in schizophrenia and anxiety.  To pursue this endeavour we use a combination of computational modelling, machine learning and brain imaging techniques such as magnetoencephalography (MEG), electroencephalography (EEG), and magnetic resonance imaging (MRI).


  +61 7 344 32435

  Garrido lab website (CJCADR)

Group Publications

Research Areas

  • Predictive Coding 
  • Schizophrenia
  • Anxiety 
  • MEG, EEG, and MRI techniques 

Group Leader

  • Dr Marta Garrido

    Affiliated Research Fellow
    Centre for Advanced Imaging
    UQ Fellow
    Queensland Brain Institute
    Affiliated Senior Lecturer
    School of Mathematics and Physics

Research Members

  • Dr Ilvana Dzafic

    Postdoctoral Research Fellow
    Queensland Brain Institute
  • Dr Kelly Garner

    Research Fellow
    Queensland Brain Institute
    Honorary Research Fellow
    School of Psychology
  • Dr Melissa Larsen

    Postdoctoral Research Fellow
    Queensland Brain Institute
  • Miss Perri Newman

    Casual Academic
    School of Mathematics and Physics
    Casual Research Assistant
    Queensland Brain Institute
  • Mr Jeremy Taylor

    Research Assistant & Research Assistant
    Queensland Brain Institute


Support Staff

  • Ms Roxanne Jemison

    Node Administrator
    Queensland Brain Institute
    Administrative Officer
    School of Mathematics and Physics

Larsen, Kit Melissa, Mørup, Morten, Birknow, Michelle Rosgaard, Fischer, Elvira, Hulme, Oliver, Vangkilde, Anders, Schmock, Henriette, Baaré, William Frans Christiaan, Didriksen, Michael, Olsen, Line, Werge, Thomas, Siebner, Hartwig R. and Garrido, Marta I. (2018) Altered auditory processing and effective connectivity in 22q11.2 deletion syndrome. Schizophrenia Research, . doi:10.1016/j.schres.2018.01.026Randeniya, R., Oestreich, L. K. L. and Garrido, M. I. (2017) Sensory prediction errors in the continuum of psychosisSchizophrenia Research, doi:10.1016/j.schres.2017.04.019

Cornwell, Brian R., Garrido, M. I., Overstreet, Cassie, Pine, Daniel S. and Grillon, Christian (2017) The un-predictive brain under threat: a neuro-computational account of anxious hypervigilanceBiological Psychiatry82 6: 447-454. doi:10.1016/j.biopsych.2017.06.031

Garrido, M. I.Rowe, E., Halasz, V., Mattingley, J. (2017) Bayesian mapping reveals that attention boosts neural responses to predicted and unpredicted stimuli. Cereb Cortex, 1-12. doi:10.1093/cercor/bhx087

Taylor, J. A.Matthews, N.Michie, P. T.Rosa, M. J. and Garrido, M. I. (2017) Auditory prediction errors as individual biomarkers of schizophreniaNeuroImage: Clinical15 264-273. doi:10.1016/j.nicl.2017.04.027

Sherwell, Chase S.Garrido, Marta I. and Cunnington, Ross (2017) Timing in predictive coding: the roles of task relevance and global probabilityJournal of Cognitive Neuroscience29 5: 780-792. doi:10.1162/jocn_a_01085

McFadyen, JessicaMermillod, MartialMattingley, Jason B.Halasz, Veronika and Garrido, Marta I. (2017) A rapid subcortical amygdala route for faces irrespective of spatial frequency and emotionJournal of Neuroscience37 14: 3864-3874. doi:10.1523/JNEUROSCI.3525-16.2017

Garrido, Marta IsabelTeng, Chee Leong JamesTaylor, Jeremy AlexanderRowe, Elise Genevieve and Mattingley, Jason Brett (2016) Surprise responses in the human brain demonstrate statistical learning under high concurrent cognitive demandn p j Science of Learning1 . doi:10.1038/npjscilearn.2016.6

Cooray, G. K.Garrido, M. I.Brismar, T. and Hyllienmark, L. (2016) The maturation of mismatch negativity networks in normal adolescenceClinical Neurophysiology127 1: 520-529. doi:10.1016/j.clinph.2015.06.026

Litvak, VladimirGarrido, MartaZeidman, Peter and Friston, Karl (2015) Empirical Bayes for group (DCM) studies: a reproducibility studyFrontiers in Human Neuroscience9 DEC: 670.1-670.12. doi:10.3389/fnhum.2015.00670

Garrido, Marta I.Barnes, Gareth R.Kumaran, DharshanMaguire, Eleanor A. and Dolan, Raymond J. (2015) Ventromedial prefrontal cortex drives hippocampal theta oscillations induced by mismatch computationsNeuroImage120 362-370. doi:10.1016/j.neuroimage.2015.07.016

Poch, ClaudiaGarrido, Marta IIgoa, Jose ManuelBelinchon, MercedesGarcia-Morales, Irene and Campo, Pablo (2015) Time-varying effective connectivity during visual object naming as a function of semantic demandsJournal of Neuroscience35 23: 8768-8776. doi:10.1523/JNEUROSCI.4888-14.2015

He, WeiGarrido, Marta I.Sowman, Paul F.Brock, Jon and Johnson, Blake W. (2015) Development of effective connectivity in the core network for face perceptionHuman Brain Mapping366: 2161-2173. doi:10.1002/hbm.22762

Rosa, Maria J.Portugal, LianaHahn, TimFallgatter, Andreas J.Garrido, Marta I.Shawe-Taylor, John and Mourao-Miranda, Janaina (2015) Sparse network-based models for patient classification using fMRINeuroImage105 493-506. doi:10.1016/j.neuroimage.2014.11.021

Dürschmid, StefanZaehle, TinoHinrichs, HermannHeinze, Hans-JochenVoges, JürgenGarrido, Marta I.Dolan, Raymond J. and Knight, Robert T. (2015) Sensory deviancy detection measured directly within the human nucleus accumbensCerebral Cortex26 3: 1168-1175. doi:10.1093/cercor/bhu304

Garvert, Mona M.Friston, Karl J.Dolan, Raymond J. and Garrido, Marta I. (2014) Subcortical amygdala pathways enable rapid face processingNeuroImage102 P2: 309-316. doi:10.1016/j.neuroimage.2014.07.047

Cooray, GeraldGarrido, Marta I.Hyllienmark, L. and Brismar, Tom (2014) A mechanistic model of mismatch negativity in the ageing brainClinical Neurophysiology125 9: 1774-1782. doi:10.1016/j.clinph.2014.01.015

Dietz, Martin J.Friston, Karl J.Mattingley, Jason B.Roepstorff, Andreas and Garrido, Marta I. (2014) Effective connectivity reveals right-hemisphere dominance in audiospatial perception: implications for models of spatial neglectJournal of Neuroscience34 14: 5003-5011. doi:10.1523/JNEUROSCI.3765-13.2014

Campo, PabloGarrido, Marta I.Moran, Rosalyn J.Garcia-Morales, IrenePoch, ClaudiaToledano, RafaelGil-Nagel, AntonioDolan, Raymond J. and Friston, Karl J. (2013) Network configuration and working memory impairment in mesial temporal lobe epilepsyNeuroImage72 48-54. doi:10.1016/j.neuroimage.2013.01.036

Garrido, Marta I.Sahani, Maneesh and Dolan, Raymond J. (2013) Outlier responses reflect sensitivity to statistical structure in the human brainPLoS Computational Biology9 3: e1002999.1-e1002999.10. doi:10.1371/journal.pcbi.1002999

Lieder, FalkDaunizeau, JeanGarrido, Marta I.Friston, Karl J. and Stephan, Klaas E. (2013) Modelling trial-by-trial changes in the mismatch negativityPLoS Computational Biology9 2: e1002911.1-e1002911.16. doi:10.1371/journal.pcbi.1002911

Lieder, FalkStephan, Klaas E.Daunizeau, JeanGarrido, Marta I. and Friston, Karl J. (2013) A Neurocomputational Model of the Mismatch NegativityPLoS Computational Biology9 11: e1003288.1-e1003288.14. doi:10.1371/journal.pcbi.1003288

Murta, TeresaLeal, AlbertoGarrido, Marta I. and Figueiredo, Patricia (2012) Dynamic Causal Modelling of epileptic seizure propagation pathways: A combined EEG-fMRI studyNeuroimage62 3: 1634-1642. doi:10.1016/j.neuroimage.2012.05.053

Garrido, Marta I. (2012) Brain connectivity: The feel of blindsightCurrent Biology22 15: R599-R600. doi:10.1016/j.cub.2012.06.012

Campo, PabloGarrido, Marta I.Moran, Rosalyn J.Maestu, FernandoGarcia-Morales, IreneGil-Nagel, Antoniodel Pozo, FranciscoDolan, Raymond J. and Friston, Karl J. (2012) Remote Effects of Hippocampal Sclerosis on Effective Connectivity during Working Memory Encoding: A Case of Connectional Diaschisis?Cerebral Cortex22 6: 1225-1236. doi:10.1093/cercor/bhr201

Garrido, Marta I.Barnes, Gareth R.Sahani, Maneesh and Dolan, Raymond J. (2012) Functional Evidence for a Dual Route to AmygdalaCurrent Biology22 2: 129-134. doi:10.1016/j.cub.2011.11.056

Boly, MelanieGarrido, Marta IsabelGosseries, OliviaBruno, Marie-AurelieBoveroux, PierreSchnakers, CarolineMassimini, MarcelloLitvak, VladimirLaureys, Steven and Friston, Karl (2011)Response to Comment on "Preserved Feedforward But Impaired Top-Down Processes in the Vegetative State"Science334 6060: . doi:10.1126/science.1210240

Boly, MelanieGarrido, Marta IsabelGosseries, OliviaBruno, Marie-AurelieBoveroux, PierreSchnakers, CarolineMassimini, MarcelloLitvak, VladimirLaureys, Steven and Friston, Karl (2011) Preserved Feedforward But Impaired Top-Down Processes in the Vegetative StateScience332 6031: 858-862. doi:10.1126/science.1202043

Garrido, Marta I.Dolan, Raymond J. and Sahani, Maneesh (2011) Surprise leads to noisier perceptual decisionsi-Perception2 2: 112-120. doi:10.1068/i0411

Garrido, Marta I.Kilner, James M.Kiebel, Stefan J.Stephan, Klaas E.Baldeweg, Torsten and Friston, Karl J.(2009) Repetition suppression and plasticity in the human brainNeuroimage48 1: 269-279. doi:10.1016/j.neuroimage.2009.06.034

Kiebel, Stefan J.Garrido, Marta I.Moran, RosalynChen, Chun-Chuan and Friston, Karl J. (2009) Dynamic causal modeling for EEG and MEGHuman Brain Mapping30 6: 1866-1876. doi:10.1002/hbm.20775

Garrido, Marta I.Kilner, James M.Kiebel, Stefan J. and Friston, Karl J. (2009) Dynamic Causal Modeling of the Response to Frequency DeviantsJournal of Neurophysiology101 5: 2620-2631. doi:10.1152/jn.90291.2008

Garrido, Marta I.Kilner, James M.Stephan, Klaas E. and Friston, Karl J. (2009) The mismatch negativity: a review of underlying mechanismsClinical Neurophysiology120 3: 453-463. doi:10.1016/j.clinph.2008.11.029

Garrido, Marta I.Friston, Karl J.Kiebel, Stefan J.Stephan, Klaas E.Baldeweg, Torsten and Kilner, James M. (2008) The functional anatomy of the MMN: A DCM study of the roving paradigmNeuroimage42 2: 936-944. doi:10.1016/j.neuroimage.2008.05.018

Kiebel, Stefan J.Garrido, Marta I.Moran, Rosalyn J. and Friston, Karl J. (2008) Dynamic causal modelling for EEG and MEGCognitive Neurodynamics2 2: 121-136. doi:10.1007/s11571-008-9038-0

Garrido, Marta I.Kilner, James M.Kiebel, Stefan J. and Friston, Karl J. (2007) Evoked brain responses are generated by feedback loopsProceedings of the National Academy of Sciences of the United States of America104 52: 20961-20966. doi:10.1073/pnas.0706274105

Garrido, Marta I.Kilner, James M.Kiebel, Stefan J.Stephan, Klaas E. and Friston, Karl J. (2007) Dynamic causal modelling of evoked potentials: A reproducibility studyNeuroimage36 3: 571-580. doi:10.1016/j.neuroimage.2007.03.014

Kiebel, Stefan J.Garrido, Marta I. and Friston, Karl J. (2007) Dynamic causal modelling of evoked responses: The role of intrinsic connectionsNeuroimage36 2: 332-345. doi:10.1016/j.neuroimage.2007.02.046

  • Professor Karl Friston, University College London
  • Professor Ray Dolan, University College London
  • Professor Klaas Stephan, University of Zurich
  • Professor Michael Breakspear, Queensland Institute for Medical Research
  • Professor Pat Michie, The University of Newcastle
  • Associate Professor Naotsugo Tsuchiya, Monash University


Senior research leader Dr Marta Garrido is trying to understand how the brain works in people with schizophrenia, so better diagnoses can be developed.

She aims to understand how the brain's circuitry is predictive and adaptive - i.e. how the brain makes predictions about future events as well as learning about, and adapting (or not) to , a new environment.